MTAP loss in metastatic breast cancer patients: Genomic landscape

by Impact Journals LLCMechanism of action of MTAP along with downstream effects from its loss. Abbreviations: MTAP: methylthioadenosine phosphorylase; MTR1P: 5-methylthioribose-1-phosphate; ODC: Ornit

Updated on: January 22,2024 16

MTAP loss in metastatic breast cancer patients: Genomic landscape

by Impact Journals LLCMechanism of action of MTAP along with downstream effects from its loss. Abbreviations: MTAP: methylthioadenosine phosphorylase; MTR1P: 5-methylthioribose-1-phosphate; ODC: Ornit

Updated on:January 22,2024 16

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on: April 07,2024 18

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on:April 07,2024 18

Liver cancer growth tied to tryptophan intake

byUTSouthwestern Medical CenterSummary of our findings on Trp dependency and vulnerability in MYC-driven tumors. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-478

Updated on: August 27,2024 0

Liver cancer growth tied to tryptophan intake

byUTSouthwestern Medical CenterSummary of our findings on Trp dependency and vulnerability in MYC-driven tumors. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-478

Updated on:August 27,2024 0

Targeting a unique metabolic pathway might starve pancreatic cancer

by Nancy Fliesler and Andrea Tamayo,Broad Institute of MIT and HarvardMItochondrial staining (red) and nuclear staining (blue) of abnormal pancreatic ducts from a mouse model of human pancreatic

Updated on: February 18,2024 17

Targeting a unique metabolic pathway might starve pancreatic cancer

by Nancy Fliesler and Andrea Tamayo,Broad Institute of MIT and HarvardMItochondrial staining (red) and nuclear staining (blue) of abnormal pancreatic ducts from a mouse model of human pancreatic

Updated on:February 18,2024 17

Rethinking how cancer cells evade targeted therapy

byUniversity of California, San FranciscoA single-cell RNA atlas of human glioblastoma through recurrence.a, An overview of genomics studies on paired longitudinal GBM specimens.b, A

Updated on: January 22,2024 17

Rethinking how cancer cells evade targeted therapy

byUniversity of California, San FranciscoA single-cell RNA atlas of human glioblastoma through recurrence.a, An overview of genomics studies on paired longitudinal GBM specimens.b, A

Updated on:January 22,2024 17

BRAF inhibitor shows promising results in pediatric patients with low-grade glioma

by American Association for Cancer ResearchGlioma of the left parietal lobe. CT scan with contrast enhancement. Credit: Mikhail Kalinin/CC BY-SA 3.0Dabrafenib (Tafinlar), a BRAF inhibitor approve

Updated on: March 30,2024 17

BRAF inhibitor shows promising results in pediatric patients with low-grade glioma

by American Association for Cancer ResearchGlioma of the left parietal lobe. CT scan with contrast enhancement. Credit: Mikhail Kalinin/CC BY-SA 3.0Dabrafenib (Tafinlar), a BRAF inhibitor approve

Updated on:March 30,2024 17

Genetically modified virus combats prostate cancer

by FAPESPIn a study with mice, a gene therapy developed in Brazil kills cancer cells and avoids adverse side effects when combined with chemotherapy. Credit: Marcos Santos / USP ImagensResearcher

Updated on: April 01,2024 19

Genetically modified virus combats prostate cancer

by FAPESPIn a study with mice, a gene therapy developed in Brazil kills cancer cells and avoids adverse side effects when combined with chemotherapy. Credit: Marcos Santos / USP ImagensResearcher

Updated on:April 01,2024 19

Routine screening for pancreatic cancer not warranted, expert panel says

(HealthDay)—There's nothing to be gained by screening for pancreatic cancer in people with no signs or symptoms of the lethal tumor, according to an influential U.S. panel of experts.Looking over

Updated on: April 01,2024 13

Routine screening for pancreatic cancer not warranted, expert panel says

(HealthDay)—There's nothing to be gained by screening for pancreatic cancer in people with no signs or symptoms of the lethal tumor, according to an influential U.S. panel of experts.Looking over

Updated on:April 01,2024 13

Researchers publish findings that could help prevent side effects for breast cancer patients

by Indiana University School of MedicineA breast cancer cell, photographed by a scanning electron microscope. Credit: Bruce Wetzel and Harry Schaefer, National Cancer Institute, National Institut

Updated on: February 23,2024 10

Researchers publish findings that could help prevent side effects for breast cancer patients

by Indiana University School of MedicineA breast cancer cell, photographed by a scanning electron microscope. Credit: Bruce Wetzel and Harry Schaefer, National Cancer Institute, National Institut

Updated on:February 23,2024 10

Researchers accurately predict how well body will fight lung cancer based on patterns of immune cells

by Case Western Reserve UniversityActual photographs of the shape of the cancer-associated immune cells. Credit: Case Western Reserve UniversityResearchers at Case Western Reserve University have

Updated on: March 01,2024 19

Researchers accurately predict how well body will fight lung cancer based on patterns of immune cells

by Case Western Reserve UniversityActual photographs of the shape of the cancer-associated immune cells. Credit: Case Western Reserve UniversityResearchers at Case Western Reserve University have

Updated on:March 01,2024 19

This 'sweet spot' could improve melanoma diagnosis

by Florida Atlantic UniversityMelanoma image example: original, i.e., no segmentation (f) and five degrees of segmentation -- from (a) through (e). Credit: Florida Atlantic UniversityToo much, to

Updated on: April 18,2024 10

This 'sweet spot' could improve melanoma diagnosis

by Florida Atlantic UniversityMelanoma image example: original, i.e., no segmentation (f) and five degrees of segmentation -- from (a) through (e). Credit: Florida Atlantic UniversityToo much, to

Updated on:April 18,2024 10

Certain gene signaling rewires tumors after immunotherapy

by Anna Megdell,University of MichiganGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2022.12.008Researchers from the University of Michigan Rogel Cancer Center ha

Updated on: January 02,2024 6

Certain gene signaling rewires tumors after immunotherapy

by Anna Megdell,University of MichiganGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2022.12.008Researchers from the University of Michigan Rogel Cancer Center ha

Updated on:January 02,2024 6