How a patient with kidney cancer overcame several metastases against all expectations

by The Spanish National Cancer Research CentreGraphical abstract. Credit:International Journal of Cancer(2023). DOI: 10.1002/ijc.3457515 years ago, a woman in her thirties was diagnos

Updated on: February 01,2024 16

How a patient with kidney cancer overcame several metastases against all expectations

by The Spanish National Cancer Research CentreGraphical abstract. Credit:International Journal of Cancer(2023). DOI: 10.1002/ijc.3457515 years ago, a woman in her thirties was diagnos

Updated on:February 01,2024 16

Study reveals potential target for precision colorectal cancer treatment

by Mallory Locklear,Yale UniversityFlowchart outlining the study. A: Metabolomics data collection and analysis; including targeted analysis of metabolites involved in ferroptosis pathways; B: Id

Updated on: February 18,2024 15

Study reveals potential target for precision colorectal cancer treatment

by Mallory Locklear,Yale UniversityFlowchart outlining the study. A: Metabolomics data collection and analysis; including targeted analysis of metabolites involved in ferroptosis pathways; B: Id

Updated on:February 18,2024 15

Lactate-producing bacteria inside tumors found to promote resistance to radiation therapy

by University of Texas M. D. Anderson Cancer CenterGraphical Abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.09.012Researchers at The University of Texas MD Anderson Can

Updated on: April 09,2024 15

Lactate-producing bacteria inside tumors found to promote resistance to radiation therapy

by University of Texas M. D. Anderson Cancer CenterGraphical Abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.09.012Researchers at The University of Texas MD Anderson Can

Updated on:April 09,2024 15

Researchers create a cell therapy based on STAb cells for a type of leukemia with few treatment options

by Josep Carreras Leukaemia Research InstituteComparative in vitro study of engineered CD1a-STAb and CD1a-CAR T cells. (A, B) Schematic diagrams showing the genetic (A) and domain structure (B) o

Updated on: February 18,2024 14

Researchers create a cell therapy based on STAb cells for a type of leukemia with few treatment options

by Josep Carreras Leukaemia Research InstituteComparative in vitro study of engineered CD1a-STAb and CD1a-CAR T cells. (A, B) Schematic diagrams showing the genetic (A) and domain structure (B) o

Updated on:February 18,2024 14

New PET tracer shows promise for uPAR-targeted therapy of neuroendocrine neoplasms

by Society of Nuclear Medicine and Molecular ImagingGraphical abstract. Credit:Journal of Nuclear Medicine(2022). DOI: 10.2967/jnumed.121.263177A novel PET radiotracer can accurately asses

Updated on: January 11,2024 13

New PET tracer shows promise for uPAR-targeted therapy of neuroendocrine neoplasms

by Society of Nuclear Medicine and Molecular ImagingGraphical abstract. Credit:Journal of Nuclear Medicine(2022). DOI: 10.2967/jnumed.121.263177A novel PET radiotracer can accurately asses

Updated on:January 11,2024 13

New insights into how tumors on adrenal glands develop

by Kyushu UniversitySteroids-producing nodules, or SPNs, exhibit a two-layered zona fasciculata (zF) and zona reticularis (zR) like structure, where two distinct cell populations might contribute

Updated on: April 06,2024 0

New insights into how tumors on adrenal glands develop

by Kyushu UniversitySteroids-producing nodules, or SPNs, exhibit a two-layered zona fasciculata (zF) and zona reticularis (zR) like structure, where two distinct cell populations might contribute

Updated on:April 06,2024 0

With vibrator used in cell phones, researchers develop 3D tumor spheroids to screen for anti-cancer drugs

by Brigham and Women’s HospitalCredit:Device(2024). DOI: 10.1016/j.device.2024.100255Depending on their location, cancer cells within a three-dimensional (3D) tumor structure can have

Updated on: March 05,2024 15

With vibrator used in cell phones, researchers develop 3D tumor spheroids to screen for anti-cancer drugs

by Brigham and Women’s HospitalCredit:Device(2024). DOI: 10.1016/j.device.2024.100255Depending on their location, cancer cells within a three-dimensional (3D) tumor structure can have

Updated on:March 05,2024 15

Natural mechanism causes 50-fold increase in T-cell activation sensitivity

byLatrobe UniversityThymic cortical T cell deletion induced by a CDR3 cysteine. TCR-retrogenic mice expressing the 6218 or 6218αC TCR were made as described in Fig.1, except that all recip

Updated on: January 22,2024 18

Natural mechanism causes 50-fold increase in T-cell activation sensitivity

byLatrobe UniversityThymic cortical T cell deletion induced by a CDR3 cysteine. TCR-retrogenic mice expressing the 6218 or 6218αC TCR were made as described in Fig.1, except that all recip

Updated on:January 22,2024 18

Tumors backfire on chemotherapy

by Ecole Polytechnique Federale de LausanneEndothelial cells (blue/grey) internalizing exosomes (red) released from chemotherapy-treated tumors. Credit: C. Cianciaruso/I. Keklikoglou/EPFLSome pat

Updated on: April 07,2024 14

Tumors backfire on chemotherapy

by Ecole Polytechnique Federale de LausanneEndothelial cells (blue/grey) internalizing exosomes (red) released from chemotherapy-treated tumors. Credit: C. Cianciaruso/I. Keklikoglou/EPFLSome pat

Updated on:April 07,2024 14

Specialised molecular profiling could allow more accurate prognosis and treatment of brain tumours

by Medical University of ViennaCredit: CC0 Public DomainMeningiomas, a type of brain tumour, are usually easy to treat. However, there are a few subtypes that follow a very aggressive course and

Updated on: April 01,2024 11

Specialised molecular profiling could allow more accurate prognosis and treatment of brain tumours

by Medical University of ViennaCredit: CC0 Public DomainMeningiomas, a type of brain tumour, are usually easy to treat. However, there are a few subtypes that follow a very aggressive course and

Updated on:April 01,2024 11

Cancer drug that targets two immune-evading tumor tactics performs well in early clinical trial

by University of PittsburghCredit: CC0 Public DomainA "two-for-one" cancer immunotherapy is potentially more effective and at least as safe as standard immunotherapies, physician-scient

Updated on: April 14,2024 18

Cancer drug that targets two immune-evading tumor tactics performs well in early clinical trial

by University of PittsburghCredit: CC0 Public DomainA "two-for-one" cancer immunotherapy is potentially more effective and at least as safe as standard immunotherapies, physician-scient

Updated on:April 14,2024 18

Findings challenge standard understanding of COVID-19 infection

by Iqbal Pittalwala,University of California - RiversideCredit: Pixabay/CC0 Public DomainSome viruses move between species. For example, SARS-CoV-2, the virus that causes COVID-19, can spill ove

Updated on: June 28,2024 4

Findings challenge standard understanding of COVID-19 infection

by Iqbal Pittalwala,University of California - RiversideCredit: Pixabay/CC0 Public DomainSome viruses move between species. For example, SARS-CoV-2, the virus that causes COVID-19, can spill ove

Updated on:June 28,2024 4