Researchers identify a regulator of breast cancer development

by UT Southwestern Medical CenterBreast cancer stem cells (BCSCs) are responsible for breast carcinogenesis. Researchers' work reveals potential targets for killing BCSCs to prevent breast tu

Updated on: January 29,2024

Researchers identify a regulator of breast cancer development

by UT Southwestern Medical CenterBreast cancer stem cells (BCSCs) are responsible for breast carcinogenesis. Researchers' work reveals potential targets for killing BCSCs to prevent breast tu

Updated on:January 29,2024

New study unveils epigenetic 'traffic lights' controlling stop and go for gene activity

by Institute of Cancer ResearchAcute depletion of SET1/COMPASS core subunits reveals rapid turnover of H3K4me3.a, Schematic of the degron systems for the targeted degradation of DPY30 and R

Updated on: February 23,2024

New study unveils epigenetic 'traffic lights' controlling stop and go for gene activity

by Institute of Cancer ResearchAcute depletion of SET1/COMPASS core subunits reveals rapid turnover of H3K4me3.a, Schematic of the degron systems for the targeted degradation of DPY30 and R

Updated on:February 23,2024

Study confirms effectiveness of newer arthritis meds

by Amy NortonNewer oral medications for rheumatoid arthritis (RA) do work quite well in the "real world," despite some doubts that they would, according to a new study.The study, of 622 adul

Updated on: May 27,2024

Study confirms effectiveness of newer arthritis meds

by Amy NortonNewer oral medications for rheumatoid arthritis (RA) do work quite well in the "real world," despite some doubts that they would, according to a new study.The study, of 622 adul

Updated on:May 27,2024

Research reveals why cancers stop responding to kinase-blocking drugs and come back stronger

by New York UniversityStructure of the FGFR kinase showing the locations of the gatekeeper residue in blue, hydrophobic spine in yellow, and ATP in cyan. Most drugs bind to the kinase in the same

Updated on: January 30,2024

Research reveals why cancers stop responding to kinase-blocking drugs and come back stronger

by New York UniversityStructure of the FGFR kinase showing the locations of the gatekeeper residue in blue, hydrophobic spine in yellow, and ATP in cyan. Most drugs bind to the kinase in the same

Updated on:January 30,2024

Team uncovers promising lead in genetic approach to treating glioblastoma

by Anna C. Christensen,University of ArizonaBaldassarre Stea, MD, PhD, (center), treats brain tumors with DNA-damaging radiation. Credit: Anna C. ChristensenGlioblastoma, a deadly brain cancer t

Updated on: May 27,2024

Team uncovers promising lead in genetic approach to treating glioblastoma

by Anna C. Christensen,University of ArizonaBaldassarre Stea, MD, PhD, (center), treats brain tumors with DNA-damaging radiation. Credit: Anna C. ChristensenGlioblastoma, a deadly brain cancer t

Updated on:May 27,2024

New anti-cancer 'degrader' targets protein essential to infant leukemia

byVan Andel Research InstituteDiscovery of a first-in-class, highly potent VHL-recruiting ENL PROTAC degrader, MS41. Credit:Science Advances(2024). DOI: 10.1126/sciadv.ado1432Scienti

Updated on: September 10,2024

New anti-cancer 'degrader' targets protein essential to infant leukemia

byVan Andel Research InstituteDiscovery of a first-in-class, highly potent VHL-recruiting ENL PROTAC degrader, MS41. Credit:Science Advances(2024). DOI: 10.1126/sciadv.ado1432Scienti

Updated on:September 10,2024

A common genetic signature has been discovered among three cancer prone rare skin diseases

by Carlos III University of MadridGene expression signature in fibroblasts from RDEB, KS and XPC patients, compared to healthy donors (a). An alteration common to the three diseases of 227 genes

Updated on: April 22,2024

A common genetic signature has been discovered among three cancer prone rare skin diseases

by Carlos III University of MadridGene expression signature in fibroblasts from RDEB, KS and XPC patients, compared to healthy donors (a). An alteration common to the three diseases of 227 genes

Updated on:April 22,2024

New study shows patient/clinician identity differences are a factor in cancer care

byJohns Hopkins University School of MedicineCredit: Unsplash/CC0 Public DomainA new study by researchers at the Johns Hopkins Kimmel Cancer Center in collaboration with Dell Medical School, Uni

Updated on: January 12,2024

New study shows patient/clinician identity differences are a factor in cancer care

byJohns Hopkins University School of MedicineCredit: Unsplash/CC0 Public DomainA new study by researchers at the Johns Hopkins Kimmel Cancer Center in collaboration with Dell Medical School, Uni

Updated on:January 12,2024

Biomarker test could improve diagnosis of endometrial cancer

by Mike Addelman,University of Manchester(a) Box plots showing the permutation importance of the plasma proteins confirmed by the Boruta algorithm to be important. (b) Crude cumulative AUC analy

Updated on: March 30,2024

Biomarker test could improve diagnosis of endometrial cancer

by Mike Addelman,University of Manchester(a) Box plots showing the permutation importance of the plasma proteins confirmed by the Boruta algorithm to be important. (b) Crude cumulative AUC analy

Updated on:March 30,2024

Study details how exosomes, released by the breast tumor, tricks cells in the blood-brain barrier into taking them up

by Children's Hospital BostonExtracellular vesicles, also known as exosomes, cross the blood-brain barrier via a transcytosis process. Credit: Kristin Johnson/Vascular Biology Program, Boston

Updated on: May 31,2024

Study details how exosomes, released by the breast tumor, tricks cells in the blood-brain barrier into taking them up

by Children's Hospital BostonExtracellular vesicles, also known as exosomes, cross the blood-brain barrier via a transcytosis process. Credit: Kristin Johnson/Vascular Biology Program, Boston

Updated on:May 31,2024

Study finds LGBTQI people in cancer survivorship 'surviving discrimination by pulling together'

by Ali Sardyga,Western Sydney UniversityInteriority landmines cycle. In this tunnel, it's mostly safe but it’s like walking in an area that has landmines. You can walk through fine for most

Updated on: January 23,2024

Study finds LGBTQI people in cancer survivorship 'surviving discrimination by pulling together'

by Ali Sardyga,Western Sydney UniversityInteriority landmines cycle. In this tunnel, it's mostly safe but it’s like walking in an area that has landmines. You can walk through fine for most

Updated on:January 23,2024

Study uncovers potential therapeutic approach for advanced prostate cancer

by Melissa Rohman,Northwestern UniversityPALI1 bridges the interaction between PRC2 (SUZ12/EZH2/EED) and G9A to catalyze dual H3K9 and H3K27 methylation, which leads to strong repression of GPS

Updated on: February 01,2024

Study uncovers potential therapeutic approach for advanced prostate cancer

by Melissa Rohman,Northwestern UniversityPALI1 bridges the interaction between PRC2 (SUZ12/EZH2/EED) and G9A to catalyze dual H3K9 and H3K27 methylation, which leads to strong repression of GPS

Updated on:February 01,2024