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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
Sub Categories on Oncology
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A CAR T cell therapy for advanced ovarian cancer developed

A CAR T cell therapy for advanced ovarian cancer developed

by City of Hope National Medical CenterMembrane-bound IL-12 engineered TAG72-CAR T cells induce higher IFNγ, T-cell expansion, and anti-tumor activity in vitro.a–cTumor cell killing o

A CAR T cell therapy for advanced ovarian cancer developed

by City of Hope National Medical CenterMembrane-bound IL-12 engineered TAG72-CAR T cells induce higher IFNγ, T-cell expansion, and anti-tumor activity in vitro.a–cTumor cell killing o
New, rare type of small cell lung cancer identified

New, rare type of small cell lung cancer identified

by Ian Demsky,Memorial Sloan Kettering Cancer CenterOn the left, four pathology images from a patient with atypical small cell lung cancer show hallmarks of carcinoid cancer in the lungs (thorax

New, rare type of small cell lung cancer identified

by Ian Demsky,Memorial Sloan Kettering Cancer CenterOn the left, four pathology images from a patient with atypical small cell lung cancer show hallmarks of carcinoid cancer in the lungs (thorax
Numbers count in the genetics of moles and melanomas

Numbers count in the genetics of moles and melanomas

by University of QueenslandReticular naevi pattern (left) Gene variations: MTAP, PLA2G6, MITF. Globular naevi pattern (right) Gene variations: IRF4. Credit: University of QueenslandUniversity of

Numbers count in the genetics of moles and melanomas

by University of QueenslandReticular naevi pattern (left) Gene variations: MTAP, PLA2G6, MITF. Globular naevi pattern (right) Gene variations: IRF4. Credit: University of QueenslandUniversity of
Palliative care in breast cancer treatment may be less likely for racial/ethnic minority patients than white patients

Palliative care in breast cancer treatment may be less likely for racial/ethnic minority patients than white patients

by American Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainDespite a steady increase in palliative care utilization from 2004 to 2020, non-Hispanic Black, Hispanic, and Asian or

Palliative care in breast cancer treatment may be less likely for racial/ethnic minority patients than white patients

by American Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainDespite a steady increase in palliative care utilization from 2004 to 2020, non-Hispanic Black, Hispanic, and Asian or
Researchers discover common markers of tumor hypoxia across 19 cancer types

Researchers discover common markers of tumor hypoxia across 19 cancer types

by Ontario Institute for Cancer ResearchUnlike healthy tissues, tumours thrive in low-oxygen environments, often acquiring the ability to resist treatment and spread to other sites in the body. Despit

Researchers discover common markers of tumor hypoxia across 19 cancer types

by Ontario Institute for Cancer ResearchUnlike healthy tissues, tumours thrive in low-oxygen environments, often acquiring the ability to resist treatment and spread to other sites in the body. Despit
Scientists develop potential stealth cancer therapy

Scientists develop potential stealth cancer therapy

by Yale Cancer Center/Smilow Cancer HospitalCredit:ACS Central Science(2024). DOI: 10.1021/acscentsci.4c00559Sneaking by cancer's defenses, by disguising tumor-fighting antibodies insi

Scientists develop potential stealth cancer therapy

by Yale Cancer Center/Smilow Cancer HospitalCredit:ACS Central Science(2024). DOI: 10.1021/acscentsci.4c00559Sneaking by cancer's defenses, by disguising tumor-fighting antibodies insi
Long-term study finds faster breast cancer radiation treatment as effective as long course

Long-term study finds faster breast cancer radiation treatment as effective as long course

by McMaster UniversityTimothy Whelan is a professor of oncology at McMaster University and a radiation oncologist at the Juravinski Cancer Centre of Hamilton Health Sciences. He holds a Canada Re

Long-term study finds faster breast cancer radiation treatment as effective as long course

by McMaster UniversityTimothy Whelan is a professor of oncology at McMaster University and a radiation oncologist at the Juravinski Cancer Centre of Hamilton Health Sciences. He holds a Canada Re
Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

by City of HopeKiller T cells surround a cancer cell. Credit: NIHKidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression wi

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

by City of HopeKiller T cells surround a cancer cell. Credit: NIHKidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression wi
Social vulnerability tied to worse pediatric head and neck cancer outcomes

Social vulnerability tied to worse pediatric head and neck cancer outcomes

by Lori SolomonAmong pediatric patients with head and neck cancers (HNCs), increasing social vulnerability is associated with significant decreases in receipt of care and survival time, according to a

Social vulnerability tied to worse pediatric head and neck cancer outcomes

by Lori SolomonAmong pediatric patients with head and neck cancers (HNCs), increasing social vulnerability is associated with significant decreases in receipt of care and survival time, according to a
Potential new series of drugs targeting cancer-driving protein BCL6

Potential new series of drugs targeting cancer-driving protein BCL6

byInstitute of Cancer ResearchThe BCL6 BTB domain dimer (in grey/green) and compound hits in pink, superimposed on each other in the main compound binding site. Credit: Dr Rob van Montfort lab /

Potential new series of drugs targeting cancer-driving protein BCL6

byInstitute of Cancer ResearchThe BCL6 BTB domain dimer (in grey/green) and compound hits in pink, superimposed on each other in the main compound binding site. Credit: Dr Rob van Montfort lab /
Destroying cancer-causing RNA could lead to bespoke treatments, say scientists

Destroying cancer-causing RNA could lead to bespoke treatments, say scientists

byPeter MacCallum Cancer CentreThe efficiency of PspCas13b silencing is highly variable between crRNAs. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-02

Destroying cancer-causing RNA could lead to bespoke treatments, say scientists

byPeter MacCallum Cancer CentreThe efficiency of PspCas13b silencing is highly variable between crRNAs. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-02
Combination therapy overcomes BET inhibitor resistance, shows study

Combination therapy overcomes BET inhibitor resistance, shows study

bySt. Jude Children's Research HospitalStudy first author Shaela Fields (Wright), from the lab of Chunliang, Li, PhD, St. Jude Department of Tumor Cell Biology, led research to understand BE

Combination therapy overcomes BET inhibitor resistance, shows study

bySt. Jude Children's Research HospitalStudy first author Shaela Fields (Wright), from the lab of Chunliang, Li, PhD, St. Jude Department of Tumor Cell Biology, led research to understand BE