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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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New treatment approach for prostate cancer could stop resistance in its tracks

New treatment approach for prostate cancer could stop resistance in its tracks

bySanford Burnham Prebys Medical Discovery InstituteProstate cancer cells. Credit: NIH Image GalleryFor the first time, researchers have discovered that prostate cancer can be killed by targetin

New treatment approach for prostate cancer could stop resistance in its tracks

bySanford Burnham Prebys Medical Discovery InstituteProstate cancer cells. Credit: NIH Image GalleryFor the first time, researchers have discovered that prostate cancer can be killed by targetin
Prostate cancer test: Is it time to ditch the digital rectal examination?

Prostate cancer test: Is it time to ditch the digital rectal examination?

by Stephen Hughes,The ConversationA man having his prostate gland examined. Credit: National Cancer Institute/WikimediaThe finger-up-the-bottom examination for prostate cancer has been drawn int

Prostate cancer test: Is it time to ditch the digital rectal examination?

by Stephen Hughes,The ConversationA man having his prostate gland examined. Credit: National Cancer Institute/WikimediaThe finger-up-the-bottom examination for prostate cancer has been drawn int
Molecular mechanisms regulating prostate cancer hypoxia identified

Molecular mechanisms regulating prostate cancer hypoxia identified

by Melissa Rohman,Northwestern UniversityMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0A Northwestern Medicine

Molecular mechanisms regulating prostate cancer hypoxia identified

by Melissa Rohman,Northwestern UniversityMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0A Northwestern Medicine
Genetic testing for prostate cancer increases after introduction of point-of-care program

Genetic testing for prostate cancer increases after introduction of point-of-care program

byWolters Kluwer HealthCredit: Unsplash/CC0 Public DomainSome patients with prostate cancer have genetic mutations that may impact their treatment. A comprehensive, on-site genetic testing progr

Genetic testing for prostate cancer increases after introduction of point-of-care program

byWolters Kluwer HealthCredit: Unsplash/CC0 Public DomainSome patients with prostate cancer have genetic mutations that may impact their treatment. A comprehensive, on-site genetic testing progr
Falling PSA levels found to predict longer survival in prostate cancer patients at high risk of metastases

Falling PSA levels found to predict longer survival in prostate cancer patients at high risk of metastases

byWolters Kluwer HealthTwelve-month landmark analysis of overall survival (OS) by prostate-specific antigen (PSA) decline subgroup for enzalutamide-treated men. Data cutoff: October 15, 2019. Cr

Falling PSA levels found to predict longer survival in prostate cancer patients at high risk of metastases

byWolters Kluwer HealthTwelve-month landmark analysis of overall survival (OS) by prostate-specific antigen (PSA) decline subgroup for enzalutamide-treated men. Data cutoff: October 15, 2019. Cr
Prostate tumor biology may be influenced by genetic ancestry

Prostate tumor biology may be influenced by genetic ancestry

byAmerican Association for Cancer ResearchSample collection sites and genetic admixture analysis. A, At clinical sites across Nigeria, 45 samples were collected. B, Admixture v1.3.0 was used to

Prostate tumor biology may be influenced by genetic ancestry

byAmerican Association for Cancer ResearchSample collection sites and genetic admixture analysis. A, At clinical sites across Nigeria, 45 samples were collected. B, Admixture v1.3.0 was used to
Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki
Potential new series of drugs targeting cancer-driving protein BCL6

Potential new series of drugs targeting cancer-driving protein BCL6

byInstitute of Cancer ResearchThe BCL6 BTB domain dimer (in grey/green) and compound hits in pink, superimposed on each other in the main compound binding site. Credit: Dr Rob van Montfort lab /

Potential new series of drugs targeting cancer-driving protein BCL6

byInstitute of Cancer ResearchThe BCL6 BTB domain dimer (in grey/green) and compound hits in pink, superimposed on each other in the main compound binding site. Credit: Dr Rob van Montfort lab /
Supercharging immunotherapy to stop breast cancer from spreading to the lung

Supercharging immunotherapy to stop breast cancer from spreading to the lung

byUniversity of GlasgowGraphical abstract. Credit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20211431Breast cancer immunotherapy could be more effective if an immune ce

Supercharging immunotherapy to stop breast cancer from spreading to the lung

byUniversity of GlasgowGraphical abstract. Credit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20211431Breast cancer immunotherapy could be more effective if an immune ce
Strong family history of prostate cancer linked to better survival

Strong family history of prostate cancer linked to better survival

byInstitute of Cancer ResearchAll-cause mortality among PrCa patients, by (A) the number of affected relatives and (B) degree of FH of the affected relatives. Deg.=degree; FH=&

Strong family history of prostate cancer linked to better survival

byInstitute of Cancer ResearchAll-cause mortality among PrCa patients, by (A) the number of affected relatives and (B) degree of FH of the affected relatives. Deg.=degree; FH=&
Link between sphingolipids and complement signaling may be key to stopping cancer metastasis

Link between sphingolipids and complement signaling may be key to stopping cancer metastasis

by Caroline Wallace,Medical University of South CarolinaGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111742MUSC Hollings Cancer Center researchers have i

Link between sphingolipids and complement signaling may be key to stopping cancer metastasis

by Caroline Wallace,Medical University of South CarolinaGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111742MUSC Hollings Cancer Center researchers have i
Cherenkov color imaging shows promise in enhancing radiation therapy effectiveness

Cherenkov color imaging shows promise in enhancing radiation therapy effectiveness

bySPIEA three-channel camera separates Cherenkov emissions into red, green, and blue channels, allowing the investigation of the impact of variations in melanin and blood levels on the signal. T

Cherenkov color imaging shows promise in enhancing radiation therapy effectiveness

bySPIEA three-channel camera separates Cherenkov emissions into red, green, and blue channels, allowing the investigation of the impact of variations in melanin and blood levels on the signal. T