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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Making melanoma immortal: Scientists discover key genetic step in cancer's race to live forever

Making melanoma immortal: Scientists discover key genetic step in cancer's race to live forever

byUniversity of PittsburghHuman chromosomes (gray) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAScientists at the University of Pittsburgh School of Medicine have discovered the mi

Making melanoma immortal: Scientists discover key genetic step in cancer's race to live forever

byUniversity of PittsburghHuman chromosomes (gray) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAScientists at the University of Pittsburgh School of Medicine have discovered the mi
Identifying drug target candidates to treat pediatric rhabdomyosarcoma tumors

Identifying drug target candidates to treat pediatric rhabdomyosarcoma tumors

by Thamarasee Jeewandara , Medical XpressscRNAseq of RMS identifies heterogeneity recapitulating muscle developmental programs. (A) Experimental workflow. (B) UMAP plot of 48,859 RMS cells after regre

Identifying drug target candidates to treat pediatric rhabdomyosarcoma tumors

by Thamarasee Jeewandara , Medical XpressscRNAseq of RMS identifies heterogeneity recapitulating muscle developmental programs. (A) Experimental workflow. (B) UMAP plot of 48,859 RMS cells after regre
Identifying the underlying causes of ovarian cancer

Identifying the underlying causes of ovarian cancer

byCedars-Sinai Medical CenterSimon Gayther, PhD, professor of Biomedical Sciences, and Michelle Jones, PhD, a research scientist in the Center for Bioinformatics and Functional Genomics, led the

Identifying the underlying causes of ovarian cancer

byCedars-Sinai Medical CenterSimon Gayther, PhD, professor of Biomedical Sciences, and Michelle Jones, PhD, a research scientist in the Center for Bioinformatics and Functional Genomics, led the
Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer

by Impact Journals LLCVolcano plot of significant differentially expressed genes with the left volcano being the discovery cohort and validation cohort on the right. Credit:Oncotarget(2022

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer

by Impact Journals LLCVolcano plot of significant differentially expressed genes with the left volcano being the discovery cohort and validation cohort on the right. Credit:Oncotarget(2022
Immune targets for chemotherapy-resistant breast cancers identified

Immune targets for chemotherapy-resistant breast cancers identified

byKing's College LondonAnalysis of stromal TILs in residual disease and prognostic implications. A) Kaplan–Meier curves for i) progression free survival and ii) overall survival in ER+HER2-

Immune targets for chemotherapy-resistant breast cancers identified

byKing's College LondonAnalysis of stromal TILs in residual disease and prognostic implications. A) Kaplan–Meier curves for i) progression free survival and ii) overall survival in ER+HER2-
How oxygen deprivation causes cancer cells to spread

How oxygen deprivation causes cancer cells to spread

byLeiden UniversityCredit: Pixabay/CC0 Public DomainIn breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis

How oxygen deprivation causes cancer cells to spread

byLeiden UniversityCredit: Pixabay/CC0 Public DomainIn breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis
Cancer in those under 50 is rising, globally. Why?

Cancer in those under 50 is rising, globally. Why?

by Siobhan Glavey,The ConversationCredit: AI-generated imageWe know what we need to do to reduce our risk of getting cancer, right? Wear SPF, stop smoking, avoid processed foods, keep fit, lose

Cancer in those under 50 is rising, globally. Why?

by Siobhan Glavey,The ConversationCredit: AI-generated imageWe know what we need to do to reduce our risk of getting cancer, right? Wear SPF, stop smoking, avoid processed foods, keep fit, lose
Cancers in adults under 50 are on the rise globally

Cancers in adults under 50 are on the rise globally

byBrigham and Women's HospitalCredit: Unsplash/CC0 Public DomainOver recent decades, more and more adults under the age of 50 are developing cancer. A study conducted by researchers from Bri

Cancers in adults under 50 are on the rise globally

byBrigham and Women's HospitalCredit: Unsplash/CC0 Public DomainOver recent decades, more and more adults under the age of 50 are developing cancer. A study conducted by researchers from Bri
Diagnostic performance of contrast-enhanced ultrasound using perfluorobutane for high-risk hepatocellular carcinoma

Diagnostic performance of contrast-enhanced ultrasound using perfluorobutane for high-risk hepatocellular carcinoma

byAmerican Roentgen Ray Society(A) Arterial-phase CEUS image (12 seconds after injection) shows 25-mm segment-8 lesion with nonrim hyperenhancement (arrow). (B) CEUS image in portal-venous phase

Diagnostic performance of contrast-enhanced ultrasound using perfluorobutane for high-risk hepatocellular carcinoma

byAmerican Roentgen Ray Society(A) Arterial-phase CEUS image (12 seconds after injection) shows 25-mm segment-8 lesion with nonrim hyperenhancement (arrow). (B) CEUS image in portal-venous phase
US approves sickle cell breakthrough with gene editing therapy

US approves sickle cell breakthrough with gene editing therapy

Credit: Unsplash/CC0 Public DomainThe United States on Friday approved a breakthrough therapy that uses revolutionary gene editing tool CRISPR to treat the debilitating blood disorder sickle cell dise

US approves sickle cell breakthrough with gene editing therapy

Credit: Unsplash/CC0 Public DomainThe United States on Friday approved a breakthrough therapy that uses revolutionary gene editing tool CRISPR to treat the debilitating blood disorder sickle cell dise
Evolving insights in blood-based liquid biopsies for prostate cancer interrogation

Evolving insights in blood-based liquid biopsies for prostate cancer interrogation

by Impact Journals LLCAnalysis of blood-based liquid biopsies in prostate cancer. Credit:Oncoscience(2023). DOI: 10.18632/oncoscience.592A new research perspective was published inOn

Evolving insights in blood-based liquid biopsies for prostate cancer interrogation

by Impact Journals LLCAnalysis of blood-based liquid biopsies in prostate cancer. Credit:Oncoscience(2023). DOI: 10.18632/oncoscience.592A new research perspective was published inOn
Noninvasive technology for the high-throughput characterization of cancer cells

Noninvasive technology for the high-throughput characterization of cancer cells

byTokyo University of ScienceSchematic of a cell rotation movement in a rotating AC electric field for (a) conventional ROT and (b) newly developed cROT. In conventional ROT in (a), when AC volt

Noninvasive technology for the high-throughput characterization of cancer cells

byTokyo University of ScienceSchematic of a cell rotation movement in a rotating AC electric field for (a) conventional ROT and (b) newly developed cROT. In conventional ROT in (a), when AC volt