Improving CAR T-cell and monoclonal antibody treatment through epitope editing

by Justin Jackson , Medical XpressCredit: CC0 Public DomainIn a paper, "Epitope editing enables targeted immunotherapy of acute myeloid leukaemia," published inNature, researchers at t

Updated on: January 07,2024 9

Improving CAR T-cell and monoclonal antibody treatment through epitope editing

by Justin Jackson , Medical XpressCredit: CC0 Public DomainIn a paper, "Epitope editing enables targeted immunotherapy of acute myeloid leukaemia," published inNature, researchers at t

Updated on:January 07,2024 9

Blocking DNA production in cancer therapy by targeting the POLtheta enzyme

by Austrian Academy of SciencesGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111716BRCA1 (BReast CAncer Gene 1), a key gene that becomes faulty in some instance

Updated on: January 07,2024 9

Blocking DNA production in cancer therapy by targeting the POLtheta enzyme

by Austrian Academy of SciencesGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111716BRCA1 (BReast CAncer Gene 1), a key gene that becomes faulty in some instance

Updated on:January 07,2024 9

Predicting condensate formation by cancer-associated fusion oncoproteins

bySt. Jude Children's Research HospitalOverview of the fusion oncoprotein (FO) database (FOdb). Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41655-2Many cancers ar

Updated on: January 07,2024 9

Predicting condensate formation by cancer-associated fusion oncoproteins

bySt. Jude Children's Research HospitalOverview of the fusion oncoprotein (FO) database (FOdb). Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41655-2Many cancers ar

Updated on:January 07,2024 9

New targets for CAR-T cell therapy against acute myeloid leukemia through AI-assisted analysis

byHelmholtz Association of German Research CentresmCSF1R CART do not cause toxicity in mice. Credit:Nature Biotechnology(2023). https://doi.org/10.1038/s41587-023-01684-0Unlike other

Updated on: January 07,2024 9

New targets for CAR-T cell therapy against acute myeloid leukemia through AI-assisted analysis

byHelmholtz Association of German Research CentresmCSF1R CART do not cause toxicity in mice. Credit:Nature Biotechnology(2023). https://doi.org/10.1038/s41587-023-01684-0Unlike other

Updated on:January 07,2024 9

Nature-inspired peptide shows anti-tumor activity

by Forschung & Bildung GmbHStructure and synthesis of kalata-type cyclotides. Pie-shaped flow chart demonstrates the solid phase peptide synthesis of kalata-type cyclotides by example of T20K. The

Updated on: January 07,2024 9

Nature-inspired peptide shows anti-tumor activity

by Forschung & Bildung GmbHStructure and synthesis of kalata-type cyclotides. Pie-shaped flow chart demonstrates the solid phase peptide synthesis of kalata-type cyclotides by example of T20K. The

Updated on:January 07,2024 9

Alternative glucose breakdown ensures the survival of cancer cells

byGerman Cancer Research CenterCredit: Pixabay/CC0 Public DomainA key enzyme in sugar metabolism is inactivated particularly easily and efficiently by oxidative stress. Scientists at the German

Updated on: January 07,2024 9

Alternative glucose breakdown ensures the survival of cancer cells

byGerman Cancer Research CenterCredit: Pixabay/CC0 Public DomainA key enzyme in sugar metabolism is inactivated particularly easily and efficiently by oxidative stress. Scientists at the German

Updated on:January 07,2024 9

Alternative bladder cancer treatment emerges amid worldwide shortage of standard of care BCG

by Jennifer Brown,University of IowaCredit: CC0 Public DomainAn on-going, worldwide shortage of bacillus Calmette-Guérin (BCG) means that many patients with a common and serious type of bladder

Updated on: January 07,2024 9

Alternative bladder cancer treatment emerges amid worldwide shortage of standard of care BCG

by Jennifer Brown,University of IowaCredit: CC0 Public DomainAn on-going, worldwide shortage of bacillus Calmette-Guérin (BCG) means that many patients with a common and serious type of bladder

Updated on:January 07,2024 9

Body mass index tied to multiple myeloma survival

by Lori SolomonUnderweight and severe obesity are associated with decreased survival in patients with multiple myeloma (MM), according to a study published online Jan. 12 in theBlood Cancer Jour

Updated on: January 07,2024 8

Body mass index tied to multiple myeloma survival

by Lori SolomonUnderweight and severe obesity are associated with decreased survival in patients with multiple myeloma (MM), according to a study published online Jan. 12 in theBlood Cancer Jour

Updated on:January 07,2024 8

Can physical exercise enhance the effect of chemotherapy against breast cancer?

byKarolinska InstitutetSchematic presentation of published evidence regarding physical activity and breast cancer. Credit:PLOS ONE(2022). DOI: 10.1371/journal.pone.0274804Approximate

Updated on: January 07,2024 8

Can physical exercise enhance the effect of chemotherapy against breast cancer?

byKarolinska InstitutetSchematic presentation of published evidence regarding physical activity and breast cancer. Credit:PLOS ONE(2022). DOI: 10.1371/journal.pone.0274804Approximate

Updated on:January 07,2024 8

Five reasons physical activity is important for cancer patients

by Kajal Gokal and Amanda Daley,The ConversationCredit: AI-generated imageYou might know that physical activity can help lower your risk of getting manycommon types of cancer. But what man

Updated on: January 07,2024 8

Five reasons physical activity is important for cancer patients

by Kajal Gokal and Amanda Daley,The ConversationCredit: AI-generated imageYou might know that physical activity can help lower your risk of getting manycommon types of cancer. But what man

Updated on:January 07,2024 8

Advance care planning produces trend toward less aggressive and more comfort-focused care for patients with cancer

byRegenstrief InstituteCredit: Pixabay/CC0 Public DomainA meta-analysis of studies involving 33,541 cancer patients evaluates the relationship between advance care planning and aggressive vs. co

Updated on: January 07,2024 9

Advance care planning produces trend toward less aggressive and more comfort-focused care for patients with cancer

byRegenstrief InstituteCredit: Pixabay/CC0 Public DomainA meta-analysis of studies involving 33,541 cancer patients evaluates the relationship between advance care planning and aggressive vs. co

Updated on:January 07,2024 9

Increased adenoma detection rate may significantly reduce post-colonoscopy colorectal cancer risk

byAmerican College of PhysiciansCredit: Pixabay/CC0 Public DomainA cohort study from the Italian Colorectal Cancer screening program including more than 49,000 colonoscopies found a significant

Updated on: January 07,2024 9

Increased adenoma detection rate may significantly reduce post-colonoscopy colorectal cancer risk

byAmerican College of PhysiciansCredit: Pixabay/CC0 Public DomainA cohort study from the Italian Colorectal Cancer screening program including more than 49,000 colonoscopies found a significant

Updated on:January 07,2024 9