Eliminating gene SRC-3 in immune cells triggers effective long-lasting anti-cancer response

byBaylor College of MedicineCredit: Unsplash/CC0 Public DomainResearchers at Baylor College of Medicine have discovered a crucial regulator of the anti-cancer immune response that could change t

Updated on: January 10,2024 10

Eliminating gene SRC-3 in immune cells triggers effective long-lasting anti-cancer response

byBaylor College of MedicineCredit: Unsplash/CC0 Public DomainResearchers at Baylor College of Medicine have discovered a crucial regulator of the anti-cancer immune response that could change t

Updated on:January 10,2024 10

Delivering oxygen to tumors may be key in overcoming radiation therapy resistance

by National Institute of Biomedical Imaging and BioengineeringOxygen in tumors is necessary for radiotherapy to effectively treat cancer, but when tumors are hypoxic, this method can fail. A new strat

Updated on: January 10,2024 10

Delivering oxygen to tumors may be key in overcoming radiation therapy resistance

by National Institute of Biomedical Imaging and BioengineeringOxygen in tumors is necessary for radiotherapy to effectively treat cancer, but when tumors are hypoxic, this method can fail. A new strat

Updated on:January 10,2024 10

Cigarette smoke and HPV have synergistic effects on cells, heightening the risk of head and neck cancer

by Julia Moióli,FAPESPHPV16 E6/E7 induces SOD2 expression in oral cells. (A) HPV16 E6/E7 transcripts were evaluated by RT-PCR in SCC143V and SCC143E6/E7 cells; β-actin was used as the control. (

Updated on: January 10,2024 15

Cigarette smoke and HPV have synergistic effects on cells, heightening the risk of head and neck cancer

by Julia Moióli,FAPESPHPV16 E6/E7 induces SOD2 expression in oral cells. (A) HPV16 E6/E7 transcripts were evaluated by RT-PCR in SCC143V and SCC143E6/E7 cells; β-actin was used as the control. (

Updated on:January 10,2024 15

Mitochondrial protein synthesis identified as a potential therapeutic target in lymphoma

byUniversity of OxfordSpleen sections from mito-QC mice immunized with SRBC and analyzed on day 12. Scale bar, 50 μm. Representative of three independent experiments. Credit:Nature Immunol

Updated on: January 10,2024 10

Mitochondrial protein synthesis identified as a potential therapeutic target in lymphoma

byUniversity of OxfordSpleen sections from mito-QC mice immunized with SRBC and analyzed on day 12. Scale bar, 50 μm. Representative of three independent experiments. Credit:Nature Immunol

Updated on:January 10,2024 10

Existing drug shows promise treating most prevalent type of lung cancer

byUniversity of KentuckyCZT binds to SRC. A. CZT binding (dashed circle) to SRC. CZT binds near the C-terminal domain of SRC and may disrupt the inactive state by preventing phosphorylation on t

Updated on: January 10,2024 6

Existing drug shows promise treating most prevalent type of lung cancer

byUniversity of KentuckyCZT binds to SRC. A. CZT binding (dashed circle) to SRC. CZT binds near the C-terminal domain of SRC and may disrupt the inactive state by preventing phosphorylation on t

Updated on:January 10,2024 6

Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

byNanyang Technological UniversitySchematic summary of mechanisms of action of ponatinib in ALT cells. Ponatinib disrupts alternative lengthening of telomeres mechanisms by inducing telomeric C-

Updated on: January 10,2024 9

Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

byNanyang Technological UniversitySchematic summary of mechanisms of action of ponatinib in ALT cells. Ponatinib disrupts alternative lengthening of telomeres mechanisms by inducing telomeric C-

Updated on:January 10,2024 9

Surgery first for colon cancer? Not so fast, according to new study

by National Comprehensive Cancer NetworkRadiologic response, TRG, and clinical T stage. (A) Radiologic response among patients with different clinical T stage; patients with cT2–3 disease were more li

Updated on: January 10,2024 9

Surgery first for colon cancer? Not so fast, according to new study

by National Comprehensive Cancer NetworkRadiologic response, TRG, and clinical T stage. (A) Radiologic response among patients with different clinical T stage; patients with cT2–3 disease were more li

Updated on:January 10,2024 9

Bacterium may decrease effectiveness of immunotherapy

by Béatrice St-Cyr-Leroux,University of MontrealAssociation between the H. pylori seropositivity status and clinical outcomes in 97 patients with advanced melanoma. A. Stacked barplot between H.

Updated on: January 10,2024 9

Bacterium may decrease effectiveness of immunotherapy

by Béatrice St-Cyr-Leroux,University of MontrealAssociation between the H. pylori seropositivity status and clinical outcomes in 97 patients with advanced melanoma. A. Stacked barplot between H.

Updated on:January 10,2024 9

Advanced imaging may help in clinical treatment of prostate cancer

byEuropean Association of UrologyCredit: Pixabay/CC0 Public DomainAn advanced imaging method is showing promise as a way to improve the diagnosis of prostate cancer by giving clinicians a cleare

Updated on: January 10,2024 9

Advanced imaging may help in clinical treatment of prostate cancer

byEuropean Association of UrologyCredit: Pixabay/CC0 Public DomainAn advanced imaging method is showing promise as a way to improve the diagnosis of prostate cancer by giving clinicians a cleare

Updated on:January 10,2024 9

Cellular senescence plays a significant role in cerebral tumors

by Marie Simon,Paris Brain InstituteCells derived from a murine glioblastoma model and embedded in a 3D extracellular matrix. Confocal microscope. Credit: Isabelle Le Roux.Glioblastomas are the

Updated on: January 10,2024 8

Cellular senescence plays a significant role in cerebral tumors

by Marie Simon,Paris Brain InstituteCells derived from a murine glioblastoma model and embedded in a 3D extracellular matrix. Confocal microscope. Credit: Isabelle Le Roux.Glioblastomas are the

Updated on:January 10,2024 8

Intracellular recycling: The key to surviving potent anti-cancer drugs

byTokyo Medical and Dental UniversityER-phagy alleviates anthracycline cardiotoxicity. Credit: Department of Cardiovascular Medicine, TMDUA cell contains many specialized subunits, called organe

Updated on: January 10,2024 10

Intracellular recycling: The key to surviving potent anti-cancer drugs

byTokyo Medical and Dental UniversityER-phagy alleviates anthracycline cardiotoxicity. Credit: Department of Cardiovascular Medicine, TMDUA cell contains many specialized subunits, called organe

Updated on:January 10,2024 10

Cell therapy could improve bone marrow transplant safety

by Tiare Dunlap,University of California, Los AngelesGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104859UCLA researchers report a step forward in the developme

Updated on: January 10,2024 9

Cell therapy could improve bone marrow transplant safety

by Tiare Dunlap,University of California, Los AngelesGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104859UCLA researchers report a step forward in the developme

Updated on:January 10,2024 9