Tumor ammonia levels inhibit T cell growth, impact immunotherapy: Study

by Anna Megdell,University of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2021). DOI: 10.1172/JCI143691High levels of ammonia in tumors leads to fewer T cell

Updated on: January 21,2024 11

Tumor ammonia levels inhibit T cell growth, impact immunotherapy: Study

by Anna Megdell,University of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2021). DOI: 10.1172/JCI143691High levels of ammonia in tumors leads to fewer T cell

Updated on:January 21,2024 11

Even when at low risk, some women should remove fallopian tubes to avoid ovarian cancer, say experts

by Cara MurezMore women, even those at low risk for ovarian cancer, who have finished having children should have their fallopian tubes removed as a precaution to prevent the deadly disease, a leading

Updated on: January 21,2024 15

Even when at low risk, some women should remove fallopian tubes to avoid ovarian cancer, say experts

by Cara MurezMore women, even those at low risk for ovarian cancer, who have finished having children should have their fallopian tubes removed as a precaution to prevent the deadly disease, a leading

Updated on:January 21,2024 15

How tumors mutate their way out of a crisis—and become drug resistant in the process

byWeizmann Institute of ScienceHuman lung cancer cells under the microscope, before (left) and after (right) treatment with an anticancer drug, which causes DNA breaks (green) in the cell nuclei

Updated on: January 21,2024 18

How tumors mutate their way out of a crisis—and become drug resistant in the process

byWeizmann Institute of ScienceHuman lung cancer cells under the microscope, before (left) and after (right) treatment with an anticancer drug, which causes DNA breaks (green) in the cell nuclei

Updated on:January 21,2024 18

Have recent efforts successfully boosted adolescent and young adult enrollment in cancer clinical trials?

byWileyDistribution of trial types by year. For each calendar year, the number of actively accruing trials for which adolescent and young adult patients were eligible is represented as a stacked

Updated on: January 21,2024 19

Have recent efforts successfully boosted adolescent and young adult enrollment in cancer clinical trials?

byWileyDistribution of trial types by year. For each calendar year, the number of actively accruing trials for which adolescent and young adult patients were eligible is represented as a stacked

Updated on:January 21,2024 19

The molecules behind metastasis

by Greta Friar,Whitehead Institute for Biomedical ResearchBreast cancer stem cells (red) that have reached the lung begin to divide into clusters that could become metastatic tumors. Credit: Art

Updated on: January 21,2024 16

The molecules behind metastasis

by Greta Friar,Whitehead Institute for Biomedical ResearchBreast cancer stem cells (red) that have reached the lung begin to divide into clusters that could become metastatic tumors. Credit: Art

Updated on:January 21,2024 16

Metastatic cancers adapt their metabolism to the tissue in which they grow

by Ulrika Ernström,Chalmers University of TechnologyMetastatic tumors adapt their metabolism to the tissue in which they grow. The image shows a primary breast cancer tumour (pink) and the metas

Updated on: January 21,2024 11

Metastatic cancers adapt their metabolism to the tissue in which they grow

by Ulrika Ernström,Chalmers University of TechnologyMetastatic tumors adapt their metabolism to the tissue in which they grow. The image shows a primary breast cancer tumour (pink) and the metas

Updated on:January 21,2024 11

Addition of metastasis-directed therapy increases PFS in prostate cancer

by Elana GotkineThe addition of metastasis-directed therapy (MDT), consisting of definitive radiation therapy to all sites of disease, to hormone therapy results in improved progression-free survival

Updated on: January 21,2024 10

Addition of metastasis-directed therapy increases PFS in prostate cancer

by Elana GotkineThe addition of metastasis-directed therapy (MDT), consisting of definitive radiation therapy to all sites of disease, to hormone therapy results in improved progression-free survival

Updated on:January 21,2024 10

Brown fat may help improve cancer survival rates

byAmerican Physiological SocietyBrown fat status is not associated with survival in patients with cancer-associated cachexia. Forest plot of the adjusted hazard ratio of brown fat predicting mor

Updated on: January 21,2024 10

Brown fat may help improve cancer survival rates

byAmerican Physiological SocietyBrown fat status is not associated with survival in patients with cancer-associated cachexia. Forest plot of the adjusted hazard ratio of brown fat predicting mor

Updated on:January 21,2024 10

Novel research shows older breast cancer survivors experience accelerated aging, worse functional outcomes

by Colleen McDonald,Medical College of WisconsinLongitudinal changes in epigenetic aging between the first and second blood samples among Black or non-Hispanic White older breast cancer survivor

Updated on: January 21,2024 12

Novel research shows older breast cancer survivors experience accelerated aging, worse functional outcomes

by Colleen McDonald,Medical College of WisconsinLongitudinal changes in epigenetic aging between the first and second blood samples among Black or non-Hispanic White older breast cancer survivor

Updated on:January 21,2024 12

Prostate cancer 'test by request' policies drive overdiagnosis and inequity with minimal benefit, argue experts

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainMost high income countries, including the U.K., do not have a national prostate cancer screening program, but instead allow men without

Updated on: January 21,2024 16

Prostate cancer 'test by request' policies drive overdiagnosis and inequity with minimal benefit, argue experts

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainMost high income countries, including the U.K., do not have a national prostate cancer screening program, but instead allow men without

Updated on:January 21,2024 16

A step towards precision oncology for patients with metastatic urothelial carcinoma

byUniversity of BonnCredit: Pixabay/CC0 Public DomainDr. Niklas Klümper, resident at the Clinic for Urology and working group leader at the Institute for Experimental Oncology at the University

Updated on: January 21,2024 16

A step towards precision oncology for patients with metastatic urothelial carcinoma

byUniversity of BonnCredit: Pixabay/CC0 Public DomainDr. Niklas Klümper, resident at the Clinic for Urology and working group leader at the Institute for Experimental Oncology at the University

Updated on:January 21,2024 16

Finding new ways to treat diffuse midline gliomas

by Greg Glasgow,CU Anschutz Medical CampusPlanning CTs demonstrating positioning of the mouse on the custom platform and RT fields for the two RT groups, along with the RT schedule for both grou

Updated on: January 16,2024 17

Finding new ways to treat diffuse midline gliomas

by Greg Glasgow,CU Anschutz Medical CampusPlanning CTs demonstrating positioning of the mouse on the custom platform and RT fields for the two RT groups, along with the RT schedule for both grou

Updated on:January 16,2024 17