Stopping a rare childhood cancer in its tracks

byCold Spring Harbor LaboratoryScientists discovered targeting a protein called ETV6 can turn Ewing sarcoma cancer cells back to normal-looking and -behaving connective tissue cells, as seen abo

Updated on: January 22,2024 18

Stopping a rare childhood cancer in its tracks

byCold Spring Harbor LaboratoryScientists discovered targeting a protein called ETV6 can turn Ewing sarcoma cancer cells back to normal-looking and -behaving connective tissue cells, as seen abo

Updated on:January 22,2024 18

Final overall study analysis continues to show benefit of sacituzumab govitecan in advanced HR+ breast cancer

byDana-Farber Cancer InstituteOverall survival in the intention-to-treat population. This is the planned final analysis of overall survival in the intent-to-treat population of all randomly assi

Updated on: January 22,2024 10

Final overall study analysis continues to show benefit of sacituzumab govitecan in advanced HR+ breast cancer

byDana-Farber Cancer InstituteOverall survival in the intention-to-treat population. This is the planned final analysis of overall survival in the intent-to-treat population of all randomly assi

Updated on:January 22,2024 10

Peripheral surrogates of tumor burden to guide therapeutic strategies for HPV-associated malignancies

by Impact Journals LLCTumor intrinsic and extrinsic factors in the periphery that can serve as proxies of tumor burden. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28487A new review

Updated on: January 22,2024 13

Peripheral surrogates of tumor burden to guide therapeutic strategies for HPV-associated malignancies

by Impact Journals LLCTumor intrinsic and extrinsic factors in the periphery that can serve as proxies of tumor burden. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28487A new review

Updated on:January 22,2024 13

Reconsidering oxygen's role in growth of tumors

byYale UniversityGraphical abstract. Credit:Cell Systems(2022). DOI: 10.1016/j.cels.2022.11.003Yale researchers have made a discovery that changes conventional thinking about the rol

Updated on: January 22,2024 14

Reconsidering oxygen's role in growth of tumors

byYale UniversityGraphical abstract. Credit:Cell Systems(2022). DOI: 10.1016/j.cels.2022.11.003Yale researchers have made a discovery that changes conventional thinking about the rol

Updated on:January 22,2024 14

Specifically designed diets demonstrate a 'powerful ability' to prevent tumorigenesis, delay tumor growth

byThe Spanish National Cancer Research CentrePrecision nutrition in cancer therapyPrecision nutrition takes into account genetic, physiological and lifestyle factors to develop personalized diet

Updated on: January 22,2024 15

Specifically designed diets demonstrate a 'powerful ability' to prevent tumorigenesis, delay tumor growth

byThe Spanish National Cancer Research CentrePrecision nutrition in cancer therapyPrecision nutrition takes into account genetic, physiological and lifestyle factors to develop personalized diet

Updated on:January 22,2024 15

The tumor environment can affect breast cancer prognosis

byLund UniversityFlowchart of included and excluded patients and representative pictures of each CAV1 staining category in stroma and cytoplasm. Credit:Translational Oncology(2022).

Updated on: January 22,2024 20

The tumor environment can affect breast cancer prognosis

byLund UniversityFlowchart of included and excluded patients and representative pictures of each CAV1 staining category in stroma and cytoplasm. Credit:Translational Oncology(2022).

Updated on:January 22,2024 20

Ethnic diversity and disparities in access to genetic testing impact prostate cancer development and treatment

byEuropean Society for Medical OncologyCredit: Unsplash/CC0 Public DomainMore than 1.4 million men were diagnosed with prostate cancer in 2020 globally, but the molecular characteristics of the

Updated on: January 22,2024 10

Ethnic diversity and disparities in access to genetic testing impact prostate cancer development and treatment

byEuropean Society for Medical OncologyCredit: Unsplash/CC0 Public DomainMore than 1.4 million men were diagnosed with prostate cancer in 2020 globally, but the molecular characteristics of the

Updated on:January 22,2024 10

Stopping the spread: Targeting tumor metastasis

by Tokyo Medical and Dental UniversityTakahashi et al. show that TGF-β generates a population of cancer cells under cell cycle arrest in G1 phase with high motility by inducing unique Slug/HMGA2-indep

Updated on: January 22,2024 15

Stopping the spread: Targeting tumor metastasis

by Tokyo Medical and Dental UniversityTakahashi et al. show that TGF-β generates a population of cancer cells under cell cycle arrest in G1 phase with high motility by inducing unique Slug/HMGA2-indep

Updated on:January 22,2024 15

'Hard to lose' mutations in tumors may predict response to immunotherapy

byJohns Hopkins University School of MedicineThe figure shows the interactions between immune cells (white) and tumor cells harboring persistent mutations (red) in the context of immunotherapy (

Updated on: January 22,2024 12

'Hard to lose' mutations in tumors may predict response to immunotherapy

byJohns Hopkins University School of MedicineThe figure shows the interactions between immune cells (white) and tumor cells harboring persistent mutations (red) in the context of immunotherapy (

Updated on:January 22,2024 12

How tumors suppress the development of metastases

byGerman Cancer Research CenterCredit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20202595Why do metastases often only appear after the original tumor has been surgicall

Updated on: January 22,2024 13

How tumors suppress the development of metastases

byGerman Cancer Research CenterCredit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20202595Why do metastases often only appear after the original tumor has been surgicall

Updated on:January 22,2024 13

MTAP loss in metastatic breast cancer patients: Genomic landscape

by Impact Journals LLCMechanism of action of MTAP along with downstream effects from its loss. Abbreviations: MTAP: methylthioadenosine phosphorylase; MTR1P: 5-methylthioribose-1-phosphate; ODC: Ornit

Updated on: January 22,2024 16

MTAP loss in metastatic breast cancer patients: Genomic landscape

by Impact Journals LLCMechanism of action of MTAP along with downstream effects from its loss. Abbreviations: MTAP: methylthioadenosine phosphorylase; MTR1P: 5-methylthioribose-1-phosphate; ODC: Ornit

Updated on:January 22,2024 16

Experts call for better cancer tests to tailor treatment

byInstitute of Cancer ResearchCredit: Pixabay/CC0 Public DomainGreater use of cancer tests is the key to tailoring use of new treatments for patients more precisely and so increasing their chanc

Updated on: January 22,2024 19

Experts call for better cancer tests to tailor treatment

byInstitute of Cancer ResearchCredit: Pixabay/CC0 Public DomainGreater use of cancer tests is the key to tailoring use of new treatments for patients more precisely and so increasing their chanc

Updated on:January 22,2024 19