Study reports progress in long-term protection against ovarian cancer tumors

byWayne State UniversityCharacterization of immune response during ovarian tumor progression. mCherry+ TKO mouse ovarian cancer cells were injected i.p. in C57BL/6 immunocompetent mice (n=50) or

Updated on: January 26,2024 20

Study reports progress in long-term protection against ovarian cancer tumors

byWayne State UniversityCharacterization of immune response during ovarian tumor progression. mCherry+ TKO mouse ovarian cancer cells were injected i.p. in C57BL/6 immunocompetent mice (n=50) or

Updated on:January 26,2024 20

New study reveals how blood cancer cells escape the immune system's natural killer cells

byUniversity of HelsinkiGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.11.008The advent of T-cell therapies, where cells of the immune system are directed towa

Updated on: January 26,2024 18

New study reveals how blood cancer cells escape the immune system's natural killer cells

byUniversity of HelsinkiGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.11.008The advent of T-cell therapies, where cells of the immune system are directed towa

Updated on:January 26,2024 18

First-in-human clinical trial of CAR T cell therapy with new binding mechanism shows promising early responses

by Perelman School of Medicine at the University of PennsylvaniaSafety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with

Updated on: January 26,2024 20

First-in-human clinical trial of CAR T cell therapy with new binding mechanism shows promising early responses

by Perelman School of Medicine at the University of PennsylvaniaSafety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with

Updated on:January 26,2024 20

The paradoxical role of white blood cells in the spread of breast cancer

byKarolinska InstitutetCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113507A new study from Karolinska Institutet,publishedinCell Reports, shows that tumor-

Updated on: January 26,2024 11

The paradoxical role of white blood cells in the spread of breast cancer

byKarolinska InstitutetCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113507A new study from Karolinska Institutet,publishedinCell Reports, shows that tumor-

Updated on:January 26,2024 11

Tumor heterogeneity and immune-evasive environment in malignant lymphoma at single-cell resolution

byUniversity of TsukubaTranscriptomic profile of T follicular helper cell lymphoma (TFHL) samples. Credit:Leukemia(2023). DOI: 10.1038/s41375-023-02093-7Researchers at the University

Updated on: January 26,2024 22

Tumor heterogeneity and immune-evasive environment in malignant lymphoma at single-cell resolution

byUniversity of TsukubaTranscriptomic profile of T follicular helper cell lymphoma (TFHL) samples. Credit:Leukemia(2023). DOI: 10.1038/s41375-023-02093-7Researchers at the University

Updated on:January 26,2024 22

Boosting immunotherapy in non-responsive cancer cells

by Surabhi Chandra,Indian Institute of ScienceAvik Chattopadhyay working in the lab. Credit: Nikita RamtekeCancer immunotherapy primes a patient's immune system to better find and destroy ca

Updated on: January 26,2024 24

Boosting immunotherapy in non-responsive cancer cells

by Surabhi Chandra,Indian Institute of ScienceAvik Chattopadhyay working in the lab. Credit: Nikita RamtekeCancer immunotherapy primes a patient's immune system to better find and destroy ca

Updated on:January 26,2024 24

BCMA+ EV levels correlate with myeloma response to belantamab-mafodotin

by Impact Journals LLCPatient examples of inverse correlation of BCMA and FLC changes during course of therapy. Credit: 2023 Springer et al.A new research paper was published inOncotarget, entit

Updated on: January 26,2024 19

BCMA+ EV levels correlate with myeloma response to belantamab-mafodotin

by Impact Journals LLCPatient examples of inverse correlation of BCMA and FLC changes during course of therapy. Credit: 2023 Springer et al.A new research paper was published inOncotarget, entit

Updated on:January 26,2024 19

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on: January 26,2024 20

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on:January 26,2024 20

Is this a faster, better treatment for blood and solid tumor cancers?

by Cynthia McCormick Hibbert,Northeastern UniversityCredit: Alyssa Stone/Northeastern UniversityA Northeastern researcher in the Department of Pharmaceutical Sciences and the New England Inflamm

Updated on: January 26,2024 13

Is this a faster, better treatment for blood and solid tumor cancers?

by Cynthia McCormick Hibbert,Northeastern UniversityCredit: Alyssa Stone/Northeastern UniversityA Northeastern researcher in the Department of Pharmaceutical Sciences and the New England Inflamm

Updated on:January 26,2024 13

Researchers translate a hypothesis into a personalized treatment for cancer

byUniversity of CalgaryFranz Zemp designed a personalized CAR T-cell therapy for a Calgary teen. Credit: Arnie Charbonneau Cancer Institute, University of CalgaryDr. Franz Zemp, Ph.D., gets chil

Updated on: January 26,2024 21

Researchers translate a hypothesis into a personalized treatment for cancer

byUniversity of CalgaryFranz Zemp designed a personalized CAR T-cell therapy for a Calgary teen. Credit: Arnie Charbonneau Cancer Institute, University of CalgaryDr. Franz Zemp, Ph.D., gets chil

Updated on:January 26,2024 21

For metastatic prostate cancer, immunotherapy may have unexpected potential

byColumbia University Irving Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.10.006Immunotherapy has been disappointing as a prostate cancer treatment, but a new Co

Updated on: January 26,2024 21

For metastatic prostate cancer, immunotherapy may have unexpected potential

byColumbia University Irving Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.10.006Immunotherapy has been disappointing as a prostate cancer treatment, but a new Co

Updated on:January 26,2024 21

Immune cell helps predict skin cancer patients' chances of responding to treatment

byKing's College Londona, Schematic of nonenzymatic extraction of lymphocytes from primary human tissue and subsequent expansion protocol. b, Summary flow cytometry data of Vδ1+cell en

Updated on: January 26,2024 23

Immune cell helps predict skin cancer patients' chances of responding to treatment

byKing's College Londona, Schematic of nonenzymatic extraction of lymphocytes from primary human tissue and subsequent expansion protocol. b, Summary flow cytometry data of Vδ1+cell en

Updated on:January 26,2024 23