Study: Mitochondria engage the integrated stress response to promote tumor growth

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper, titled "Mitochondria engage the integrated stress response to promote tumor growth," was published inOncot

Updated on: January 30,2024 13

Study: Mitochondria engage the integrated stress response to promote tumor growth

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper, titled "Mitochondria engage the integrated stress response to promote tumor growth," was published inOncot

Updated on:January 30,2024 13

Billions spent on cancer research but only small percentage goes to treatment, study shows

by University of SouthamptonFunding per year by type of science (A) and proportion of funding per year by type of science (B). Credit:The Lancet Oncology(2023). DOI: 10.1016/S1470-204

Updated on: January 30,2024 13

Billions spent on cancer research but only small percentage goes to treatment, study shows

by University of SouthamptonFunding per year by type of science (A) and proportion of funding per year by type of science (B). Credit:The Lancet Oncology(2023). DOI: 10.1016/S1470-204

Updated on:January 30,2024 13

Researchers identify potential biomarker to distinguish two aggressive types of brain tumors in children

by Johns Hopkins University School of MedicineSMYD3 overexpression activates the EGFR pathway in CHLA01 cells. (A) Localization of endogenous SMYD3. Representative 60x Z-stack confocal images sho

Updated on: January 30,2024 20

Researchers identify potential biomarker to distinguish two aggressive types of brain tumors in children

by Johns Hopkins University School of MedicineSMYD3 overexpression activates the EGFR pathway in CHLA01 cells. (A) Localization of endogenous SMYD3. Representative 60x Z-stack confocal images sho

Updated on:January 30,2024 20

Long-term collection of patient-reported outcome data in oncology trials: Important and feasible

by Institute for Quality and Efficiency in Health CareCredit: CC0 Public DomainPatient-reported outcome (PRO) data are collected in oncology trials to determine patients' perspectives of canc

Updated on: January 30,2024 10

Long-term collection of patient-reported outcome data in oncology trials: Important and feasible

by Institute for Quality and Efficiency in Health CareCredit: CC0 Public DomainPatient-reported outcome (PRO) data are collected in oncology trials to determine patients' perspectives of canc

Updated on:January 30,2024 10

A new method for conducting a liquid biopsy for liver cancer

by Bob Yirka , Medical XpressComparison between mutation and methylation fractions in the same cfDNA sample. (A) The correlation between the AF based on mutation and methylation. (B) Comparison of the

Updated on: January 30,2024 12

A new method for conducting a liquid biopsy for liver cancer

by Bob Yirka , Medical XpressComparison between mutation and methylation fractions in the same cfDNA sample. (A) The correlation between the AF based on mutation and methylation. (B) Comparison of the

Updated on:January 30,2024 12

Research reveals why cancers stop responding to kinase-blocking drugs and come back stronger

by New York UniversityStructure of the FGFR kinase showing the locations of the gatekeeper residue in blue, hydrophobic spine in yellow, and ATP in cyan. Most drugs bind to the kinase in the same

Updated on: January 30,2024 16

Research reveals why cancers stop responding to kinase-blocking drugs and come back stronger

by New York UniversityStructure of the FGFR kinase showing the locations of the gatekeeper residue in blue, hydrophobic spine in yellow, and ATP in cyan. Most drugs bind to the kinase in the same

Updated on:January 30,2024 16

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on: January 30,2024 12

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on:January 30,2024 12

A new nutrition-screening tool for the oncologic population

byScience China PressVenn plots of three screening tools and malnutrition defined by PG-SGA. Malnutrition was defined as a PG-SGA score of ≥4. The malnutrition risk in MST was defined as an MST

Updated on: January 30,2024 20

A new nutrition-screening tool for the oncologic population

byScience China PressVenn plots of three screening tools and malnutrition defined by PG-SGA. Malnutrition was defined as a PG-SGA score of ≥4. The malnutrition risk in MST was defined as an MST

Updated on:January 30,2024 20

Quitting smoking early linked with improved survival rates for people diagnosed with lung cancer

byHarvard T.H. Chan School of Public HealthCredit: Pixabay/CC0 Public DomainQuitting smoking early was associated with higher survival rates following a lung cancer diagnosis, according to a new

Updated on: January 30,2024 11

Quitting smoking early linked with improved survival rates for people diagnosed with lung cancer

byHarvard T.H. Chan School of Public HealthCredit: Pixabay/CC0 Public DomainQuitting smoking early was associated with higher survival rates following a lung cancer diagnosis, according to a new

Updated on:January 30,2024 11

Novel machine-learning blood test detects cancers with genome-wide mutations in single molecules of cell-free DNA

by Amy Mone,Johns Hopkins UniversitySchematic of overall approach for cancer detection using single-molecule cfDNA sequencing. Credit:Nature Genetics(2023). DOI: 10.1038/s41588-023-0

Updated on: January 30,2024 15

Novel machine-learning blood test detects cancers with genome-wide mutations in single molecules of cell-free DNA

by Amy Mone,Johns Hopkins UniversitySchematic of overall approach for cancer detection using single-molecule cfDNA sequencing. Credit:Nature Genetics(2023). DOI: 10.1038/s41588-023-0

Updated on:January 30,2024 15

Novel prognostic index to predict survival outcomes in gastric cancer patients

by Impact Journals LLCCancer-specific survival curve based on the inflammation-based prognostic index. Abbreviation: ICPI: inflammation based prognostic index. Credit:Oncotarget(2023). DOI

Updated on: January 30,2024 17

Novel prognostic index to predict survival outcomes in gastric cancer patients

by Impact Journals LLCCancer-specific survival curve based on the inflammation-based prognostic index. Abbreviation: ICPI: inflammation based prognostic index. Credit:Oncotarget(2023). DOI

Updated on:January 30,2024 17

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on: January 30,2024 11

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on:January 30,2024 11