Researchers revisit potent drug as promising treatment for acute leukemia

by National University of SingaporeChemical screening using the GIMAP enhancer reporter system. (A) Overview of the chemical screening strategy. Using a liquid handling workstation, 2,961 compoun

Updated on: February 03,2024 11

Researchers revisit potent drug as promising treatment for acute leukemia

by National University of SingaporeChemical screening using the GIMAP enhancer reporter system. (A) Overview of the chemical screening strategy. Using a liquid handling workstation, 2,961 compoun

Updated on:February 03,2024 11

Team discovers broken 'brake' of cancer mutation machine

by UT Southwestern Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.010Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that

Updated on: February 03,2024 15

Team discovers broken 'brake' of cancer mutation machine

by UT Southwestern Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.010Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that

Updated on:February 03,2024 15

Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

by Strata OncologyDevelopment of an integrative immunotherapy response score (IRS) model to stratify PD-(L)1 therapy benefit in patients with advanced solid tumors.aReal-world treatment an

Updated on: February 03,2024 19

Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

by Strata OncologyDevelopment of an integrative immunotherapy response score (IRS) model to stratify PD-(L)1 therapy benefit in patients with advanced solid tumors.aReal-world treatment an

Updated on:February 03,2024 19

Researchers report results in rare gynecologic cancers from DART immunotherapy trial

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainResults from the S1609 DART clinical trial, which tested an immunotherapy combination of ipilimumab plus nivolumab in 53 cohorts of pat

Updated on: February 03,2024 18

Researchers report results in rare gynecologic cancers from DART immunotherapy trial

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainResults from the S1609 DART clinical trial, which tested an immunotherapy combination of ipilimumab plus nivolumab in 53 cohorts of pat

Updated on:February 03,2024 18

A novel method to better predict the outgrowth of ductal carcinoma in situ

by Netherlands Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.002An international team of researchers led by the Netherlands Cancer Institu

Updated on: February 03,2024 10

A novel method to better predict the outgrowth of ductal carcinoma in situ

by Netherlands Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.002An international team of researchers led by the Netherlands Cancer Institu

Updated on:February 03,2024 10

Study hints at how cancer immunotherapy can be safer

by Bill Hathaway,Yale UniversityCredit: Unsplash/CC0 Public DomainCancer immunotherapy has revolutionized treatment of many forms of cancer by unleashing the immune system response against tumor

Updated on: February 03,2024 10

Study hints at how cancer immunotherapy can be safer

by Bill Hathaway,Yale UniversityCredit: Unsplash/CC0 Public DomainCancer immunotherapy has revolutionized treatment of many forms of cancer by unleashing the immune system response against tumor

Updated on:February 03,2024 10

Study brings new understanding of multiple myeloma evolution

by University of Texas M. D. Anderson Cancer CenterGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.05.007A new study by researchers at The University of Texas

Updated on: February 03,2024 10

Study brings new understanding of multiple myeloma evolution

by University of Texas M. D. Anderson Cancer CenterGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.05.007A new study by researchers at The University of Texas

Updated on:February 03,2024 10

Family of DNA damage–inducing microbial metabolites found in guts of people with IBD

by Bob Yirka , Medical XpressHuman gut microbes isolated from IBD patients produce small-molecule genotoxins. Diverse gut microbes isolated from patients with IBD exhibit direct genotoxicity. M. morga

Updated on: February 03,2024 19

Family of DNA damage–inducing microbial metabolites found in guts of people with IBD

by Bob Yirka , Medical XpressHuman gut microbes isolated from IBD patients produce small-molecule genotoxins. Diverse gut microbes isolated from patients with IBD exhibit direct genotoxicity. M. morga

Updated on:February 03,2024 19

Study explores current pharmacy practice in cardio-oncology

by Milana Madzarac,University of WaterlooCredit: Unsplash/CC0 Public DomainA structured support system for oncology patients is one of the most important aspects during a difficult time in someo

Updated on: February 03,2024 19

Study explores current pharmacy practice in cardio-oncology

by Milana Madzarac,University of WaterlooCredit: Unsplash/CC0 Public DomainA structured support system for oncology patients is one of the most important aspects during a difficult time in someo

Updated on:February 03,2024 19

Researchers discover how malignant melanoma eludes immune cells

by Alan Dove,Columbia University Irving Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.05.014Malignant melanoma, a dangerous type of skin cancer, deploys an elegan

Updated on: February 03,2024 17

Researchers discover how malignant melanoma eludes immune cells

by Alan Dove,Columbia University Irving Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.05.014Malignant melanoma, a dangerous type of skin cancer, deploys an elegan

Updated on:February 03,2024 17

Ewing sarcoma tumors can be split into two groups for targeted care

by Cincinnati Children's Hospital Medical CenterA. Bright field images of CCH1 and CCH2 cells B. CCH1 and CCH2 cells cells stained with antibody towards CD99 (green) and DAPI (blue) C. Wester

Updated on: February 03,2024 12

Ewing sarcoma tumors can be split into two groups for targeted care

by Cincinnati Children's Hospital Medical CenterA. Bright field images of CCH1 and CCH2 cells B. CCH1 and CCH2 cells cells stained with antibody towards CD99 (green) and DAPI (blue) C. Wester

Updated on:February 03,2024 12

Research reveals promising new combination treatment for bladder cancer patients

by Memorial Sloan Kettering Cancer CenterCredit: OpenStax College, CC BY 3.0, via Wikimedia CommonsResearchers from Memorial Sloan Kettering Cancer Center (MSK) shared a promising treatment

Updated on: February 03,2024 11

Research reveals promising new combination treatment for bladder cancer patients

by Memorial Sloan Kettering Cancer CenterCredit: OpenStax College, CC BY 3.0, via Wikimedia CommonsResearchers from Memorial Sloan Kettering Cancer Center (MSK) shared a promising treatment

Updated on:February 03,2024 11