Molecule Linking Cancer Driver and Cell Death Genes May Be Effective Against DLBCL

November 2023Thomas R. CollinsMolecules that link cancer driver genes and promoters of cell death genes produce potent killing of diffuse large B-cell lymphoma (DLBCL) cells, according to findings pub

Updated on: February 18,2024 12

Molecule Linking Cancer Driver and Cell Death Genes May Be Effective Against DLBCL

November 2023Thomas R. CollinsMolecules that link cancer driver genes and promoters of cell death genes produce potent killing of diffuse large B-cell lymphoma (DLBCL) cells, according to findings pub

Updated on:February 18,2024 12

IKZF1 Alterations an Independent Marker of AML Risk

February 2024Leah LawrenceMutatedIKZF1was an independent marker of adverse risk in patients with acute myeloid leukemia (AML), and patients whose AML had these alterations were at higher r

Updated on: February 18,2024 14

IKZF1 Alterations an Independent Marker of AML Risk

February 2024Leah LawrenceMutatedIKZF1was an independent marker of adverse risk in patients with acute myeloid leukemia (AML), and patients whose AML had these alterations were at higher r

Updated on:February 18,2024 14

FDA Approves Two Cell-Based SCD Gene Therapies

February 2024The U.S. Food and Drug Administration (FDA) approved exagamglogene autotemcel (exa-cel) and lovotibeglogene autotemcel (lovo-cel) for the treatment of sickle cell disease (SCD) in patient

Updated on: February 18,2024 6

FDA Approves Two Cell-Based SCD Gene Therapies

February 2024The U.S. Food and Drug Administration (FDA) approved exagamglogene autotemcel (exa-cel) and lovotibeglogene autotemcel (lovo-cel) for the treatment of sickle cell disease (SCD) in patient

Updated on:February 18,2024 6

Does this cause cancer? How scientists determine whether a chemical is carcinogenic

by Brad Reisfeld,The ConversationPeople areexposed to numerous chemicalsthroughout their lifetimes. These chemicals can be from the air, foods, personal care items, household product

Updated on: February 18,2024 16

Does this cause cancer? How scientists determine whether a chemical is carcinogenic

by Brad Reisfeld,The ConversationPeople areexposed to numerous chemicalsthroughout their lifetimes. These chemicals can be from the air, foods, personal care items, household product

Updated on:February 18,2024 16

Researchers image live drug response and resistant 'pockets' in pancreatic cancer

by Garvan Institute of Medical ResearchSchematic of spatiotemporal AKT activity mapping in several organ systems in vivo.Optical window–mediated intravital assessment of metabolic and malignancy-

Updated on: February 18,2024 10

Researchers image live drug response and resistant 'pockets' in pancreatic cancer

by Garvan Institute of Medical ResearchSchematic of spatiotemporal AKT activity mapping in several organ systems in vivo.Optical window–mediated intravital assessment of metabolic and malignancy-

Updated on:February 18,2024 10

Certain cancers will likely rise exponentially due to COVID-19 screening delays

byAmerican College of SurgeonsCredit: Unsplash/CC0 Public DomainDelays in cancer screening during the COVID-19 pandemic will likely cause a significant increase in cancer cases that could have b

Updated on: February 18,2024 20

Certain cancers will likely rise exponentially due to COVID-19 screening delays

byAmerican College of SurgeonsCredit: Unsplash/CC0 Public DomainDelays in cancer screening during the COVID-19 pandemic will likely cause a significant increase in cancer cases that could have b

Updated on:February 18,2024 20

Research suggests a new approach for treatment-resistant breast cancers

by Louisiana State UniversityCB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (15

Updated on: February 18,2024 10

Research suggests a new approach for treatment-resistant breast cancers

by Louisiana State UniversityCB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (15

Updated on:February 18,2024 10

Researchers find an epigenetic key that unlocks common deadly cancers

by Katherine Fenz,Rockefeller UniversityLesions (in green) akin to basal cell carcinoma that were induced by SOX9 in the epidermis. Abnormal differentiation is shown in red, and blue marks cell

Updated on: February 18,2024 18

Researchers find an epigenetic key that unlocks common deadly cancers

by Katherine Fenz,Rockefeller UniversityLesions (in green) akin to basal cell carcinoma that were induced by SOX9 in the epidermis. Abnormal differentiation is shown in red, and blue marks cell

Updated on:February 18,2024 18

Study: Palliative care provided at point of oncology surgery does not improve patient outcomes

by Vanderbilt University Medical CenterCredit: Unsplash/CC0 Public DomainOne of the most important advances in palliative care in oncology over the past 15 years has been the recognition that pal

Updated on: February 18,2024 18

Study: Palliative care provided at point of oncology surgery does not improve patient outcomes

by Vanderbilt University Medical CenterCredit: Unsplash/CC0 Public DomainOne of the most important advances in palliative care in oncology over the past 15 years has been the recognition that pal

Updated on:February 18,2024 18

Researchers use a new approach to hit an 'undruggable' target

by University of MichiganGraphical abstract. Credit:Nature Chemical Biology(2023). DOI: 10.1038/s41589-022-01248-4The protein STAT5 has long been an appealing target against cancer, b

Updated on: February 18,2024 20

Researchers use a new approach to hit an 'undruggable' target

by University of MichiganGraphical abstract. Credit:Nature Chemical Biology(2023). DOI: 10.1038/s41589-022-01248-4The protein STAT5 has long been an appealing target against cancer, b

Updated on:February 18,2024 20

Study reveals potential target for precision colorectal cancer treatment

by Mallory Locklear,Yale UniversityFlowchart outlining the study. A: Metabolomics data collection and analysis; including targeted analysis of metabolites involved in ferroptosis pathways; B: Id

Updated on: February 18,2024 15

Study reveals potential target for precision colorectal cancer treatment

by Mallory Locklear,Yale UniversityFlowchart outlining the study. A: Metabolomics data collection and analysis; including targeted analysis of metabolites involved in ferroptosis pathways; B: Id

Updated on:February 18,2024 15

Researchers make miniature 'bone marrows in a dish' to improve anti-cancer treatments

by University of BirminghamA cross section of a mini bone marrow organoids showing cells that produce blood platelets, in a network of blood vessels. Credit: Dr A Khan, University of BirminghamSc

Updated on: February 18,2024 17

Researchers make miniature 'bone marrows in a dish' to improve anti-cancer treatments

by University of BirminghamA cross section of a mini bone marrow organoids showing cells that produce blood platelets, in a network of blood vessels. Credit: Dr A Khan, University of BirminghamSc

Updated on:February 18,2024 17