Research identifies new target that may prevent blood cancer

by Bill Snyder,Vanderbilt University Medical CenterCredit: Unsplash/CC0 Public DomainAn international coalition of biomedical researchers co-led by Alexander Bick, MD, Ph.D., at Vanderbilt Unive

Updated on: February 18,2024 14

Research identifies new target that may prevent blood cancer

by Bill Snyder,Vanderbilt University Medical CenterCredit: Unsplash/CC0 Public DomainAn international coalition of biomedical researchers co-led by Alexander Bick, MD, Ph.D., at Vanderbilt Unive

Updated on:February 18,2024 14

A CAR T cell therapy for advanced ovarian cancer developed

by City of Hope National Medical CenterMembrane-bound IL-12 engineered TAG72-CAR T cells induce higher IFNγ, T-cell expansion, and anti-tumor activity in vitro.a–cTumor cell killing o

Updated on: February 18,2024 10

A CAR T cell therapy for advanced ovarian cancer developed

by City of Hope National Medical CenterMembrane-bound IL-12 engineered TAG72-CAR T cells induce higher IFNγ, T-cell expansion, and anti-tumor activity in vitro.a–cTumor cell killing o

Updated on:February 18,2024 10

'Collateral damage' from normal cell function may cause mutations that play a role in cancer

by Wellcome Trust Sanger InstituteSpatial distribution of APOBEC-positive crypts. APOBEC-positive crypts and their surrounding crypts before microdissection with their SBS mutational spectrums. S

Updated on: February 18,2024 12

'Collateral damage' from normal cell function may cause mutations that play a role in cancer

by Wellcome Trust Sanger InstituteSpatial distribution of APOBEC-positive crypts. APOBEC-positive crypts and their surrounding crypts before microdissection with their SBS mutational spectrums. S

Updated on:February 18,2024 12

Researchers uncover racial and ethnic disparities in a widely used precision oncology data registry

by Katie Marquedant,Massachusetts General HospitalSample size estimation to detect differences in mutational proportions between white and racial/ethnic minority patients at varying power increm

Updated on: February 18,2024 16

Researchers uncover racial and ethnic disparities in a widely used precision oncology data registry

by Katie Marquedant,Massachusetts General HospitalSample size estimation to detect differences in mutational proportions between white and racial/ethnic minority patients at varying power increm

Updated on:February 18,2024 16

Long-term exposure to nitrates in drinking water may be a risk factor for prostate cancer

by Barcelona Institute for Global HealthCredit: Pixabay/CC0 Public DomainThe nitrate ingested over the course of a person's adult lifetime through the consumption of tap water and bottled wat

Updated on: February 18,2024 16

Long-term exposure to nitrates in drinking water may be a risk factor for prostate cancer

by Barcelona Institute for Global HealthCredit: Pixabay/CC0 Public DomainThe nitrate ingested over the course of a person's adult lifetime through the consumption of tap water and bottled wat

Updated on:February 18,2024 16

Researchers develop new marker for cancer cell motility

by Leipzig UniversityTwo aggregate states of cancer cell clusters. In blue: densely packed, more rounded cancer cells jam together and cannot move, reducing the risk of metastasis. In green: more

Updated on: February 18,2024 12

Researchers develop new marker for cancer cell motility

by Leipzig UniversityTwo aggregate states of cancer cell clusters. In blue: densely packed, more rounded cancer cells jam together and cannot move, reducing the risk of metastasis. In green: more

Updated on:February 18,2024 12

New immunotherapy targeting tumor macrophages to tackle lung cancer

by Germans Trias i Pujol Research InstituteRImAb modifies the intratumoral myeloid cell compartment in a mouse model of LLC. a) Myeloid cell gating classification using the expression of surface marke

Updated on: February 18,2024 15

New immunotherapy targeting tumor macrophages to tackle lung cancer

by Germans Trias i Pujol Research InstituteRImAb modifies the intratumoral myeloid cell compartment in a mouse model of LLC. a) Myeloid cell gating classification using the expression of surface marke

Updated on:February 18,2024 15

Investigating the role of fatty acids in cancer cell survival

by Melissa Rohman,Northwestern UniversityIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous ep

Updated on: February 18,2024 17

Investigating the role of fatty acids in cancer cell survival

by Melissa Rohman,Northwestern UniversityIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous ep

Updated on:February 18,2024 17

Researchers shed light on signaling pathway responsible for head and neck cancers

by Gina DiGravio,Boston University School of MedicineCausal Inference Models of Interactions Between Pathways/Cell States in Head and Neck Cancer scRNAseq Data. A. Causal inference graphs indica

Updated on: February 18,2024 11

Researchers shed light on signaling pathway responsible for head and neck cancers

by Gina DiGravio,Boston University School of MedicineCausal Inference Models of Interactions Between Pathways/Cell States in Head and Neck Cancer scRNAseq Data. A. Causal inference graphs indica

Updated on:February 18,2024 11

Cervical cancer burden remains high in many countries; scale-up needed to meet 2030 elimination target

by LancetHigh grade dysplasia (carcinoma in situ) in the uterine cervix. The abnormal epithelium is extending into a mucus gland to the left of centre. This disease can progress to invasive cance

Updated on: February 18,2024 18

Cervical cancer burden remains high in many countries; scale-up needed to meet 2030 elimination target

by LancetHigh grade dysplasia (carcinoma in situ) in the uterine cervix. The abnormal epithelium is extending into a mucus gland to the left of centre. This disease can progress to invasive cance

Updated on:February 18,2024 18

Researchers discover connection between stress-activated signaling and immune cell evasion in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.08.016Anti-cancer immune cells are critical to inhibiti

Updated on: February 18,2024 14

Researchers discover connection between stress-activated signaling and immune cell evasion in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.08.016Anti-cancer immune cells are critical to inhibiti

Updated on:February 18,2024 14

Aggressive surgery increases survival with low-grade brain tumors: Study

by University of California, San FranciscoCredit: Unsplash/CC0 Public DomainThe transition of a low-grade, slow growing brain tumor to a lethal one can be delayed if neurosurgeons remove as much

Updated on: February 18,2024 13

Aggressive surgery increases survival with low-grade brain tumors: Study

by University of California, San FranciscoCredit: Unsplash/CC0 Public DomainThe transition of a low-grade, slow growing brain tumor to a lethal one can be delayed if neurosurgeons remove as much

Updated on:February 18,2024 13