A comprehensive proteogenomic dataset to help cancer researchers unravel molecular mysteries

by National Institutes of HealthTumor types and data types of the CPTAC pan-cancer dataset. Overview of the available molecular data types for the CPTAC pan-cancer cohort (n= 1072, see Tabl

Updated on: February 20,2024 12

A comprehensive proteogenomic dataset to help cancer researchers unravel molecular mysteries

by National Institutes of HealthTumor types and data types of the CPTAC pan-cancer dataset. Overview of the available molecular data types for the CPTAC pan-cancer cohort (n= 1072, see Tabl

Updated on:February 20,2024 12

Researchers discover a new approach to boost the immune system

by Aarhus UniversityCancer cells. Credit: Dr. Cecil Fox, National Cancer InstituteImmunotherapy is a type of cancer treatment that uses the body's own immune system to fight tumor cells. Whil

Updated on: February 20,2024 20

Researchers discover a new approach to boost the immune system

by Aarhus UniversityCancer cells. Credit: Dr. Cecil Fox, National Cancer InstituteImmunotherapy is a type of cancer treatment that uses the body's own immune system to fight tumor cells. Whil

Updated on:February 20,2024 20

Researchers develop 'Goldilocks drug' to treat triple-negative breast cancer

by Mikayla Mace Kelley,University of ArizonacSNX1.3 competitively inhibits binding of EGFR to SNX1.ARibbon drawing of EGFR kinase domain (PDB ID 5CNO) and SNX1 Bar domain (PDB ID 4FZ

Updated on: February 20,2024 11

Researchers develop 'Goldilocks drug' to treat triple-negative breast cancer

by Mikayla Mace Kelley,University of ArizonacSNX1.3 competitively inhibits binding of EGFR to SNX1.ARibbon drawing of EGFR kinase domain (PDB ID 5CNO) and SNX1 Bar domain (PDB ID 4FZ

Updated on:February 20,2024 11

Researchers make major advance with cancer-killing antibody-drug conjugates

by Doug Bennett,University of FloridaCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.2c01771Building a new precision cancer treatment comes with no shortage of

Updated on: February 20,2024 18

Researchers make major advance with cancer-killing antibody-drug conjugates

by Doug Bennett,University of FloridaCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.2c01771Building a new precision cancer treatment comes with no shortage of

Updated on:February 20,2024 18

Cancer-targeting virus therapy combined with radiation more effective against brain cancer than either one alone

by Gillian Rutherford,University of AlbertaResearchers Mary Hitt (left) and Quinn Storozynsky found that using a cancer-targeting virus therapy at the same time as radiation gives more benefit t

Updated on: February 19,2024 14

Cancer-targeting virus therapy combined with radiation more effective against brain cancer than either one alone

by Gillian Rutherford,University of AlbertaResearchers Mary Hitt (left) and Quinn Storozynsky found that using a cancer-targeting virus therapy at the same time as radiation gives more benefit t

Updated on:February 19,2024 14

A cell surface marker for identifying tumor-initiating cells in pancreatic cancer

by Kumamoto UniversityROR1 is a cell surface receptor that promotes hyperproliferation, metastasis, and relapse in PDAC when highly expressed. Suppressing ROR1 reduces PDAC growth. Credit: Masaya

Updated on: February 19,2024 15

A cell surface marker for identifying tumor-initiating cells in pancreatic cancer

by Kumamoto UniversityROR1 is a cell surface receptor that promotes hyperproliferation, metastasis, and relapse in PDAC when highly expressed. Suppressing ROR1 reduces PDAC growth. Credit: Masaya

Updated on:February 19,2024 15

A study refines a molecular marker that accurately predicts the recurrence of aggressive meningiomas

by Texas Children's HospitalCredit: Pixabay/CC0 Public DomainDrs. Akash Patel and Tiemo Klisch, investigators at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Childr

Updated on: February 19,2024 17

A study refines a molecular marker that accurately predicts the recurrence of aggressive meningiomas

by Texas Children's HospitalCredit: Pixabay/CC0 Public DomainDrs. Akash Patel and Tiemo Klisch, investigators at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Childr

Updated on:February 19,2024 17

AI-powered ultrasound imaging that detects breast cancer

by Pohang University of Science & Technology (POSTECH)Research Image. Credit: POSTECHBreast cancer undisputedly has the highest incidence rate in female patients. Moreover, out of the six major ca

Updated on: February 19,2024 19

AI-powered ultrasound imaging that detects breast cancer

by Pohang University of Science & Technology (POSTECH)Research Image. Credit: POSTECHBreast cancer undisputedly has the highest incidence rate in female patients. Moreover, out of the six major ca

Updated on:February 19,2024 19

Illuminating tumor cells with dark proteins

by Columbia UniversityRibosome roadblock effect: comparing the AMD1 tail sequence, poly(A) and the XBP1 stalling sequence. a–e, Reporter constructs shown on the left were transfected into HEK293T

Updated on: February 19,2024 10

Illuminating tumor cells with dark proteins

by Columbia UniversityRibosome roadblock effect: comparing the AMD1 tail sequence, poly(A) and the XBP1 stalling sequence. a–e, Reporter constructs shown on the left were transfected into HEK293T

Updated on:February 19,2024 10

Researchers identify barriers to breast cancer screening in vulnerable populations

by Sbarro Health Research OrganizationCredit: Unsplash/CC0 Public DomainWomen of racial and ethnic minorities experience challenges that hinder adherence to regular mammography screenings.In order to

Updated on: February 18,2024 19

Researchers identify barriers to breast cancer screening in vulnerable populations

by Sbarro Health Research OrganizationCredit: Unsplash/CC0 Public DomainWomen of racial and ethnic minorities experience challenges that hinder adherence to regular mammography screenings.In order to

Updated on:February 18,2024 19

Researchers report on inhibitory effect of glioblastoma signals to macrophages

by University of BaselGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0"Don't eat me," is how one might translate the signal that the cancer cells in a glioblastoma sen

Updated on: February 18,2024 14

Researchers report on inhibitory effect of glioblastoma signals to macrophages

by University of BaselGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0"Don't eat me," is how one might translate the signal that the cancer cells in a glioblastoma sen

Updated on:February 18,2024 14

New treatment trialed in mice offers hope for advanced liver cancer

by Centenary InstituteCD5-2 treatment improved tumor vessels structure. Representative scanning electron microscopy images of liver tumor blood vessels in the different treatment groups. Qualitat

Updated on: February 18,2024 19

New treatment trialed in mice offers hope for advanced liver cancer

by Centenary InstituteCD5-2 treatment improved tumor vessels structure. Representative scanning electron microscopy images of liver tumor blood vessels in the different treatment groups. Qualitat

Updated on:February 18,2024 19