Promising new treatment for deadly pediatric tumors

by Konstanze Adam, Wilhelm Sander-StiftungA simplified schematic of the DNA damage repair pathways. Below there is the curves showing cell viability in response to the ATR inhibitors (AZD6738 and BAY

Updated on: February 23,2024 10

Promising new treatment for deadly pediatric tumors

by Konstanze Adam, Wilhelm Sander-StiftungA simplified schematic of the DNA damage repair pathways. Below there is the curves showing cell viability in response to the ATR inhibitors (AZD6738 and BAY

Updated on:February 23,2024 10

Researchers identify genes that cause rare hidden cancer

by Garvan Institute of Medical ResearchIHC staining of human sarcoma cells (myxoid liposarcoma). Credit: Garvan Institute of Medical ResearchSeveral genes that cause sarcoma have been identified

Updated on: February 23,2024 16

Researchers identify genes that cause rare hidden cancer

by Garvan Institute of Medical ResearchIHC staining of human sarcoma cells (myxoid liposarcoma). Credit: Garvan Institute of Medical ResearchSeveral genes that cause sarcoma have been identified

Updated on:February 23,2024 16

Increased mitochondria and lipid turnover reduces risk for liver cancer

by University of Chicago Medical CenterLoss of BNIP3 promotes HCC initiation and tumor growth. (A) Representative images of HCC tumors forming in the liver of Bnip3+/+and bnip3−/−mice

Updated on: February 23,2024 17

Increased mitochondria and lipid turnover reduces risk for liver cancer

by University of Chicago Medical CenterLoss of BNIP3 promotes HCC initiation and tumor growth. (A) Representative images of HCC tumors forming in the liver of Bnip3+/+and bnip3−/−mice

Updated on:February 23,2024 17

Researchers discover a molecule that helps pancreas cells mature and limits tumor formation

by The Spanish National Cancer Research CentrePancreatic acinar cells undergoing inflammation. Credit: / Isidoro Cobo. CNIOThe pancreas, located behind the stomach, manages the energy supply in o

Updated on: February 23,2024 20

Researchers discover a molecule that helps pancreas cells mature and limits tumor formation

by The Spanish National Cancer Research CentrePancreatic acinar cells undergoing inflammation. Credit: / Isidoro Cobo. CNIOThe pancreas, located behind the stomach, manages the energy supply in o

Updated on:February 23,2024 20

Drug combo breaks down cancer resistance to immunotherapy

by Ecole Polytechnique Federale de LausanneA schematic summary of the study. Credit: Douglas Hanahan (EPFL)Immunotherapy is a way of treating cancer by reprogramming the patient's immune syst

Updated on: February 23,2024 14

Drug combo breaks down cancer resistance to immunotherapy

by Ecole Polytechnique Federale de LausanneA schematic summary of the study. Credit: Douglas Hanahan (EPFL)Immunotherapy is a way of treating cancer by reprogramming the patient's immune syst

Updated on:February 23,2024 14

A new drug target for triple-negative breast cancer

by Louisiana State UniversityCredit: Louisiana State UniversityResearch led by Dr. Suresh Alahari, Professor of Biochemistry at LSU Health New Orleans' Schools of Medicine and Graduate Studie

Updated on: February 23,2024 10

A new drug target for triple-negative breast cancer

by Louisiana State UniversityCredit: Louisiana State UniversityResearch led by Dr. Suresh Alahari, Professor of Biochemistry at LSU Health New Orleans' Schools of Medicine and Graduate Studie

Updated on:February 23,2024 10

Study points toward new ways to prevent liver cancer

by Columbia University Irving Medical CenterCharacterization of genetic mutations, inflammation, immune cell and tumor markers in mice with genetic HSC depletion, activation of inhibition. Credit

Updated on: February 23,2024 15

Study points toward new ways to prevent liver cancer

by Columbia University Irving Medical CenterCharacterization of genetic mutations, inflammation, immune cell and tumor markers in mice with genetic HSC depletion, activation of inhibition. Credit

Updated on:February 23,2024 15

New study unveils epigenetic 'traffic lights' controlling stop and go for gene activity

by Institute of Cancer ResearchAcute depletion of SET1/COMPASS core subunits reveals rapid turnover of H3K4me3.a, Schematic of the degron systems for the targeted degradation of DPY30 and R

Updated on: February 23,2024 20

New study unveils epigenetic 'traffic lights' controlling stop and go for gene activity

by Institute of Cancer ResearchAcute depletion of SET1/COMPASS core subunits reveals rapid turnover of H3K4me3.a, Schematic of the degron systems for the targeted degradation of DPY30 and R

Updated on:February 23,2024 20

The right moves: How studying cell movement during embryonic development may offer new insights into cancer metastasis

by Ian Demsky,Memorial Sloan Kettering Cancer CenterUnder the microscope, MSK scientists studied how cells in a mouse embryo (green) move out and break away from their original tissue by contrac

Updated on: February 23,2024 12

The right moves: How studying cell movement during embryonic development may offer new insights into cancer metastasis

by Ian Demsky,Memorial Sloan Kettering Cancer CenterUnder the microscope, MSK scientists studied how cells in a mouse embryo (green) move out and break away from their original tissue by contrac

Updated on:February 23,2024 12

Dietary change starves cancer cells, overcoming treatment resistance

by University of MichiganGreen staining shows mTORC1 is significantly increased due to disruption in GATOR1 in a mouse model of colon cancer. Credit: Sumeet SolankiA dietary change could be a key

Updated on: February 23,2024 13

Dietary change starves cancer cells, overcoming treatment resistance

by University of MichiganGreen staining shows mTORC1 is significantly increased due to disruption in GATOR1 in a mouse model of colon cancer. Credit: Sumeet SolankiA dietary change could be a key

Updated on:February 23,2024 13

Researchers publish findings that could help prevent side effects for breast cancer patients

by Indiana University School of MedicineA breast cancer cell, photographed by a scanning electron microscope. Credit: Bruce Wetzel and Harry Schaefer, National Cancer Institute, National Institut

Updated on: February 23,2024 10

Researchers publish findings that could help prevent side effects for breast cancer patients

by Indiana University School of MedicineA breast cancer cell, photographed by a scanning electron microscope. Credit: Bruce Wetzel and Harry Schaefer, National Cancer Institute, National Institut

Updated on:February 23,2024 10

Study reveals a trio of immune cells vital in response to liver cancer immunotherapy

by The Mount Sinai HospitalThe study revealed how certain immune cell interactions in tumors facilitate response to checkpoint blockade, pointing to potential new approaches to cancer immunothera

Updated on: February 23,2024 19

Study reveals a trio of immune cells vital in response to liver cancer immunotherapy

by The Mount Sinai HospitalThe study revealed how certain immune cell interactions in tumors facilitate response to checkpoint blockade, pointing to potential new approaches to cancer immunothera

Updated on:February 23,2024 19