Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on: April 08,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on:April 08,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on: August 08,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on:August 08,2024

FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on: November 22,2024

FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on:November 22,2024

New study finds a 67% increase in neurovascular imaging use for headache and dizziness in the emergency department

by Harvey L. Neiman Health Policy InstituteCredit: CC0 Public DomainNew research demonstrates that the use of CT angiography (CTA) for patients with headache or dizziness increased dramatically over f

Updated on: March 30,2024

New study finds a 67% increase in neurovascular imaging use for headache and dizziness in the emergency department

by Harvey L. Neiman Health Policy InstituteCredit: CC0 Public DomainNew research demonstrates that the use of CT angiography (CTA) for patients with headache or dizziness increased dramatically over f

Updated on:March 30,2024

Could disease pathogens be the dark matter behind Alzheimer's disease?

by Richard Harth,Arizona State UniversityCould viruses, bacteria or other infectious pathogens play a role in the onset or progression of Alzheimer's disease? A new Viewpoint article discuss

Updated on: June 18,2024

Could disease pathogens be the dark matter behind Alzheimer's disease?

by Richard Harth,Arizona State UniversityCould viruses, bacteria or other infectious pathogens play a role in the onset or progression of Alzheimer's disease? A new Viewpoint article discuss

Updated on:June 18,2024

A new breakthrough in Alzheimer's disease research: Visualizing reactive astrocyte-neuron interaction

by Institute for Basic ScienceFig. 1. Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acet

Updated on: April 16,2024

A new breakthrough in Alzheimer's disease research: Visualizing reactive astrocyte-neuron interaction

by Institute for Basic ScienceFig. 1. Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acet

Updated on:April 16,2024

Inflammatory changes in the brain twenty years before Alzheimer onset

by Karolinska InstitutetSome of the researcher's PET-images.Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, ac

Updated on: February 27,2024

Inflammatory changes in the brain twenty years before Alzheimer onset

by Karolinska InstitutetSome of the researcher's PET-images.Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, ac

Updated on:February 27,2024

Diagnosis of Alzheimer's and related dementias reduces social activity

by Rutgers UniversityCredit: Pixabay/CC0 Public DomainDespite the belief that early diagnosis of Alzheimer's disease and other dementias is crucial, a new Rutgers study found that the diagnos

Updated on: April 20,2024

Diagnosis of Alzheimer's and related dementias reduces social activity

by Rutgers UniversityCredit: Pixabay/CC0 Public DomainDespite the belief that early diagnosis of Alzheimer's disease and other dementias is crucial, a new Rutgers study found that the diagnos

Updated on:April 20,2024

Alzheimer's disease: Viagra is seen as a potential treatment, but the research shows contradictory findings

by Ian Maidment and Hayley Gorton,The ConversationCredit: CC0 Public DomainArecent study reportedthat sildenafil, sold under the brand name Viagra, and other medicines from the same

Updated on: March 22,2024

Alzheimer's disease: Viagra is seen as a potential treatment, but the research shows contradictory findings

by Ian Maidment and Hayley Gorton,The ConversationCredit: CC0 Public DomainArecent study reportedthat sildenafil, sold under the brand name Viagra, and other medicines from the same

Updated on:March 22,2024

Lecanemab: Experimental drug is a ray of hope for Alzheimer's disease

by Frederic Calon and Étienne Aumont,The ConversationCredit: AI-generated imageOn Nov. 30, Eisai and Biogen announced theresults of their latest phase 3 clinical trial in Alzheimer's d

Updated on: March 30,2024

Lecanemab: Experimental drug is a ray of hope for Alzheimer's disease

by Frederic Calon and Étienne Aumont,The ConversationCredit: AI-generated imageOn Nov. 30, Eisai and Biogen announced theresults of their latest phase 3 clinical trial in Alzheimer's d

Updated on:March 30,2024

30 years on, are we winning the fight against Alzheimer's?

by Suzanne Leigh, University of CaliforniaA set of 16 brain PET scans, with orange areas representing Alzheimer's progression. Credit: UC San FranciscoUC San Francisco experts say that we have rea

Updated on: March 13,2024

30 years on, are we winning the fight against Alzheimer's?

by Suzanne Leigh, University of CaliforniaA set of 16 brain PET scans, with orange areas representing Alzheimer's progression. Credit: UC San FranciscoUC San Francisco experts say that we have rea

Updated on:March 13,2024

Could sudden infant death syndrome be caused by unrecognized brain infections?

by Nancy Fliesler,Children's Hospital BostonCredit: Pixabay/CC0 Public DomainSome infants who pass away from sudden infant death syndrome (SIDS) are known to have had acute minor infections.

Updated on: March 30,2024

Could sudden infant death syndrome be caused by unrecognized brain infections?

by Nancy Fliesler,Children's Hospital BostonCredit: Pixabay/CC0 Public DomainSome infants who pass away from sudden infant death syndrome (SIDS) are known to have had acute minor infections.

Updated on:March 30,2024