From autism to Alzheimer's: A large-scale animal study links brain pH changes to wide-ranging cognitive issues

byFujita Health UniversityIncreased brain lactate levels correlated with decreased pH are associated with poor working memory. Credit: eLife (2024). DOI: 10.7554/eLife.89376.3A global collaborat

Updated on: March 28,2024

From autism to Alzheimer's: A large-scale animal study links brain pH changes to wide-ranging cognitive issues

byFujita Health UniversityIncreased brain lactate levels correlated with decreased pH are associated with poor working memory. Credit: eLife (2024). DOI: 10.7554/eLife.89376.3A global collaborat

Updated on:March 28,2024

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on: July 31,2024

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on:July 31,2024

New insights into causes of loss of orientation in dementia

by University of ExeterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.New research has revealed how disease-associated changes in two interlinked n

Updated on: February 27,2024

New insights into causes of loss of orientation in dementia

by University of ExeterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.New research has revealed how disease-associated changes in two interlinked n

Updated on:February 27,2024

Removing large brain artery clot, chased with clot-buster shot may improve stroke outcomes

byAmerican Heart AssociationCredit: Pixabay/CC0 Public DomainRemoving a blood clot from a large brain artery, then injecting the clot-dissolving drug tenecteplase into the artery resulted in str

Updated on: March 03,2025

Removing large brain artery clot, chased with clot-buster shot may improve stroke outcomes

byAmerican Heart AssociationCredit: Pixabay/CC0 Public DomainRemoving a blood clot from a large brain artery, then injecting the clot-dissolving drug tenecteplase into the artery resulted in str

Updated on:March 03,2025

Genes, cardiovascular health each factor into dementia risk

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainGenes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. res

Updated on: June 14,2024

Genes, cardiovascular health each factor into dementia risk

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainGenes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. res

Updated on:June 14,2024

Computational techniques explore 'the dark side of amyloid aggregation in the brain'

by Jianhan Chen,University of Massachusetts AmherstPET scan of a human brain with Alzheimer's disease. Credit: public domainAs physicians and families know too well, though Alzheimer's d

Updated on: June 18,2024

Computational techniques explore 'the dark side of amyloid aggregation in the brain'

by Jianhan Chen,University of Massachusetts AmherstPET scan of a human brain with Alzheimer's disease. Credit: public domainAs physicians and families know too well, though Alzheimer's d

Updated on:June 18,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on: April 28,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on:April 28,2024

Risk for dementia diagnosis up for seniors with schizophrenia

Older adults with schizophrenia have an increased risk for receiving a diagnosis of dementia compared with those without serious mental illness (SMI), according to a study published in the June issue

Updated on: June 11,2024

Risk for dementia diagnosis up for seniors with schizophrenia

Older adults with schizophrenia have an increased risk for receiving a diagnosis of dementia compared with those without serious mental illness (SMI), according to a study published in the June issue

Updated on:June 11,2024

Understanding removal of brain fluid provides avenue for Alzheimer's treatment

by Alzheimer's Research UKResearchers in Switzerland have investigated the way fluid is removed from around the brain. Finding a new pathway for its removal, their work may signal a paradigm

Updated on: March 07,2024

Understanding removal of brain fluid provides avenue for Alzheimer's treatment

by Alzheimer's Research UKResearchers in Switzerland have investigated the way fluid is removed from around the brain. Finding a new pathway for its removal, their work may signal a paradigm

Updated on:March 07,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Is that 'midlife crisis' really Alzheimer's disease?

by Carmela Tartaglia,The ConversationCredit: AI-generated imageImagine you tell your 55 year-old mom you're going to get married and she's too disorganized to help you with the wedding p

Updated on: March 13,2024

Is that 'midlife crisis' really Alzheimer's disease?

by Carmela Tartaglia,The ConversationCredit: AI-generated imageImagine you tell your 55 year-old mom you're going to get married and she's too disorganized to help you with the wedding p

Updated on:March 13,2024

Innovative 'smart socks' could help millions living with dementia

by University of BristolLeft: The display that carers will see in the Milbotix app. Right: Milbotix founder and CEO Dr Zeke Steer. Credit: University of Bristol"Smart socks" that track

Updated on: May 13,2024

Innovative 'smart socks' could help millions living with dementia

by University of BristolLeft: The display that carers will see in the Milbotix app. Right: Milbotix founder and CEO Dr Zeke Steer. Credit: University of Bristol"Smart socks" that track

Updated on:May 13,2024