Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on: January 11,2024 10

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on:January 11,2024 10

How a single synapse transmits both visual and subconscious information to the brain of fruit flies

by Justin Jackson , Medical XpressACh and histamine act on distinct neurons. Credit:Nature(2023). DOI: 10.1038/s41586-023-06681-6Research led by Peking University, China, has discovered a

Updated on: January 12,2024 20

How a single synapse transmits both visual and subconscious information to the brain of fruit flies

by Justin Jackson , Medical XpressACh and histamine act on distinct neurons. Credit:Nature(2023). DOI: 10.1038/s41586-023-06681-6Research led by Peking University, China, has discovered a

Updated on:January 12,2024 20

Anxiety may be contagious, mouse study suggests

bySociety for NeuroscienceCredit: CC0 Public DomainSevere instances of stress experienced early in life (ELS) are a risk factor for developing neuropsychiatric diseases, such as anxiety, later i

Updated on: January 12,2024 16

Anxiety may be contagious, mouse study suggests

bySociety for NeuroscienceCredit: CC0 Public DomainSevere instances of stress experienced early in life (ELS) are a risk factor for developing neuropsychiatric diseases, such as anxiety, later i

Updated on:January 12,2024 16

Oxytocin spreads cooperation in social networks

by Society for NeuroscienceSchematic of the artificial social networks in the cooperation games. Credit: Li et al.,JNeurosci2022Administering oxytocin to the central members of a soci

Updated on: February 18,2024 17

Oxytocin spreads cooperation in social networks

by Society for NeuroscienceSchematic of the artificial social networks in the cooperation games. Credit: Li et al.,JNeurosci2022Administering oxytocin to the central members of a soci

Updated on:February 18,2024 17

Structure of adult brain, previously thought to be fixed, is changed by treatment

by European College of NeuropsychopharmacologyRepresentative map of the affected connections in the brain. The number of these connections increased after treatment. Credit: Jonathan ReppleScient

Updated on: February 05,2024 18

Structure of adult brain, previously thought to be fixed, is changed by treatment

by European College of NeuropsychopharmacologyRepresentative map of the affected connections in the brain. The number of these connections increased after treatment. Credit: Jonathan ReppleScient

Updated on:February 05,2024 18

Patients with Alzheimer's disease, dementia face twice the risk of dying after ICU discharge

by American Association of Critical-Care Nurses (AACN)Outcomes after a stay in the intensive care unit for patients in cohorts with versus without Alzheimer disease and related dementia (ADRD). Credit

Updated on: April 02,2024 11

Patients with Alzheimer's disease, dementia face twice the risk of dying after ICU discharge

by American Association of Critical-Care Nurses (AACN)Outcomes after a stay in the intensive care unit for patients in cohorts with versus without Alzheimer disease and related dementia (ADRD). Credit

Updated on:April 02,2024 11

New insight into role of amyloid beta in Alzheimer's disease

by Tamara Bhandari,Washington University School of Medicine in St. LouisA new technique for measuring levels in the brain of amyloid beta, a key protein associated with Alzheimer’s disease, woul

Updated on: April 02,2024 16

New insight into role of amyloid beta in Alzheimer's disease

by Tamara Bhandari,Washington University School of Medicine in St. LouisA new technique for measuring levels in the brain of amyloid beta, a key protein associated with Alzheimer’s disease, woul

Updated on:April 02,2024 16

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024 0

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024 0

Chemist discovers promising compound for a future drug against Alzheimer's disease

by RUDN UniversityCredit: RUDN UniversityBiochemists from RUDN University (Russia) and the University of Bari (Italy) report a group of compounds that can become a molecular scaffold for new drug

Updated on: June 07,2024 5

Chemist discovers promising compound for a future drug against Alzheimer's disease

by RUDN UniversityCredit: RUDN UniversityBiochemists from RUDN University (Russia) and the University of Bari (Italy) report a group of compounds that can become a molecular scaffold for new drug

Updated on:June 07,2024 5

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on: January 12,2024 10

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on:January 12,2024 10

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on: April 18,2024 19

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on:April 18,2024 19

New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late

by Soeren Mattke and Ying Liu,The ConversationCredit: Pixabay/CC0 Public DomainMild cognitive impairment—an early stage of dementia—is widely underdiagnosed in people 65 and older. That is the k

Updated on: March 28,2024 0

New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late

by Soeren Mattke and Ying Liu,The ConversationCredit: Pixabay/CC0 Public DomainMild cognitive impairment—an early stage of dementia—is widely underdiagnosed in people 65 and older. That is the k

Updated on:March 28,2024 0