Alzheimer's disease is partly genetic—studying the genes that delay decline in some may lead to treatments for all

by Steven DeKosky,The ConversationCredit: Unsplash/CC0 Public DomainDiseases that run in families usually have genetic causes. Some aregenetic mutationsthat directly cause the diseas

Updated on: March 02,2024 13

Alzheimer's disease is partly genetic—studying the genes that delay decline in some may lead to treatments for all

by Steven DeKosky,The ConversationCredit: Unsplash/CC0 Public DomainDiseases that run in families usually have genetic causes. Some aregenetic mutationsthat directly cause the diseas

Updated on:March 02,2024 13

The genome guardian turns to the dark side: Opportunity for drug discovery against cancer?

by Publicase Comunicação CientíficaUnder normal conditions, native p53 protein is folded but when chemicals and/or high pressure are applied the protein may unfold and loose its 3D structure. Dur

Updated on: June 14,2024 6

The genome guardian turns to the dark side: Opportunity for drug discovery against cancer?

by Publicase Comunicação CientíficaUnder normal conditions, native p53 protein is folded but when chemicals and/or high pressure are applied the protein may unfold and loose its 3D structure. Dur

Updated on:June 14,2024 6

Counting from left to right feels 'natural,' but new research shows our brains count faster from bottom to top

by Luke Greenacre, Adrian Dyer, Jair Garcia and Scarlett Howard,The ConversationTesting how participants show preferences for either horizontal or vertical mental number lines by indicating the

Updated on: February 18,2024 11

Counting from left to right feels 'natural,' but new research shows our brains count faster from bottom to top

by Luke Greenacre, Adrian Dyer, Jair Garcia and Scarlett Howard,The ConversationTesting how participants show preferences for either horizontal or vertical mental number lines by indicating the

Updated on:February 18,2024 11

Immune cells of the brain are not all the same: New research could open novel therapeutic pathways

by University of HelsinkiMicroglia (in red) surround an ARG1+microglia cell (in yellow) that expresses the enzyme ARG1. Credit: Vassilis StratouliasA recent study published inNature Neurosc

Updated on: February 21,2024 15

Immune cells of the brain are not all the same: New research could open novel therapeutic pathways

by University of HelsinkiMicroglia (in red) surround an ARG1+microglia cell (in yellow) that expresses the enzyme ARG1. Credit: Vassilis StratouliasA recent study published inNature Neurosc

Updated on:February 21,2024 15

Stem cells model genetic risk for developing Alzheimer's disease

by International Society for Stem Cell ResearchCholesterol oversupply from ApoE4 astrocytes promote Aβ production in neurons. Credit: Jinsoo SeoNew research published inStem Cell Reportsha

Updated on: June 04,2024 4

Stem cells model genetic risk for developing Alzheimer's disease

by International Society for Stem Cell ResearchCholesterol oversupply from ApoE4 astrocytes promote Aβ production in neurons. Credit: Jinsoo SeoNew research published inStem Cell Reportsha

Updated on:June 04,2024 4

Research into the nature of memory reveals how cells that store information are stabilized over time

byUniversity at BuffaloDheeraj Roy, Ph.D., assistant professor in the Department of Physiology and Biophysics in the Jacobs School of Medicine and Biomedical Sciences at UB, is a senior author o

Updated on: April 09,2024 0

Research into the nature of memory reveals how cells that store information are stabilized over time

byUniversity at BuffaloDheeraj Roy, Ph.D., assistant professor in the Department of Physiology and Biophysics in the Jacobs School of Medicine and Biomedical Sciences at UB, is a senior author o

Updated on:April 09,2024 0

4D printing allows flexible electrodes for nerve stimulation

byTechnical University MunichFor the conductive structures, a thin layer of gold is deposited onto the 3D printed structure under high vacuum. Credit: Andreas Heddergott / TUMSpecific nerves may

Updated on: January 21,2024 10

4D printing allows flexible electrodes for nerve stimulation

byTechnical University MunichFor the conductive structures, a thin layer of gold is deposited onto the 3D printed structure under high vacuum. Credit: Andreas Heddergott / TUMSpecific nerves may

Updated on:January 21,2024 10

Exploring the link between early life stress and maladaptive behavior across species

by Ingrid Fadelli , Medical XpressEarly life stressors induce long-term alterations in central mechanisms that drive appropriate social interactions. Being social species, most individuals gain pleasu

Updated on: January 09,2024 10

Exploring the link between early life stress and maladaptive behavior across species

by Ingrid Fadelli , Medical XpressEarly life stressors induce long-term alterations in central mechanisms that drive appropriate social interactions. Being social species, most individuals gain pleasu

Updated on:January 09,2024 10

Single-cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C

by Impact Journals LLC(A) Representative images and quantification of Aβ stained with thioflavin S in the hippocampus and cortex of 5xFAD mice treated with or without APC. (B) Radial arm water maze te

Updated on: March 20,2024 17

Single-cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C

by Impact Journals LLC(A) Representative images and quantification of Aβ stained with thioflavin S in the hippocampus and cortex of 5xFAD mice treated with or without APC. (B) Radial arm water maze te

Updated on:March 20,2024 17

The brain pays attention to unfamiliar voices during sleep

by Society for NeuroscienceTemporal aspects of the difference in the triggered K-complexes and micro-arousals. LEFT: The difference between UFV and FV in the number of triggered K-complexes was s

Updated on: February 21,2024 6

The brain pays attention to unfamiliar voices during sleep

by Society for NeuroscienceTemporal aspects of the difference in the triggered K-complexes and micro-arousals. LEFT: The difference between UFV and FV in the number of triggered K-complexes was s

Updated on:February 21,2024 6

Alzheimer's drug donanemab has been hailed as a turning point. But what does it mean for people with the disease?

by Steve Macfarlane,The ConversationCredit: AI-generated imageTrial results of a new drug to treat Alzheimer's disease, donanemab, shows it canslow cognitive declineby 35%. The d

Updated on: April 16,2024 18

Alzheimer's drug donanemab has been hailed as a turning point. But what does it mean for people with the disease?

by Steve Macfarlane,The ConversationCredit: AI-generated imageTrial results of a new drug to treat Alzheimer's disease, donanemab, shows it canslow cognitive declineby 35%. The d

Updated on:April 16,2024 18

Parkinson's disease study develops analytical pipeline to identify unexploited genes

byHiroshima UniversityA pipeline to explore candidate target genes using transcriptomics and unknomics. Credit: Takayuki Suzuki/Hiroshima UniversityA research team from Hiroshima University has

Updated on: September 15,2024 0

Parkinson's disease study develops analytical pipeline to identify unexploited genes

byHiroshima UniversityA pipeline to explore candidate target genes using transcriptomics and unknomics. Credit: Takayuki Suzuki/Hiroshima UniversityA research team from Hiroshima University has

Updated on:September 15,2024 0