New atlas of mRNA variants captures inner workings of the brain

byWeill Cornell Medical CollegeSummary of mouse brain cell subtype assignments by age and region. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01616-4Investigators at We

Updated on: April 27,2024

New atlas of mRNA variants captures inner workings of the brain

byWeill Cornell Medical CollegeSummary of mouse brain cell subtype assignments by age and region. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01616-4Investigators at We

Updated on:April 27,2024

Organoids reveal an overlooked protein's role in traumatic brain injury

by Cell PressOrganoid with neurons labeled in green. Credit: Josh BerlindClinicians often find limited success in treating patients with traumatic brain injury, a condition long linked to contact

Updated on: April 06,2024

Organoids reveal an overlooked protein's role in traumatic brain injury

by Cell PressOrganoid with neurons labeled in green. Credit: Josh BerlindClinicians often find limited success in treating patients with traumatic brain injury, a condition long linked to contact

Updated on:April 06,2024

Evidence doesn't support spinal cord stimulators for chronic back pain—and they could cause harm, say researchers

by Ian Harris, Adrian C Traeger and Caitlin Jones,The ConversationCredit: CC0 Public DomainIn an episode ofABC's "Four Corners"this week, the use of spinal cord stimula

Updated on: April 28,2024

Evidence doesn't support spinal cord stimulators for chronic back pain—and they could cause harm, say researchers

by Ian Harris, Adrian C Traeger and Caitlin Jones,The ConversationCredit: CC0 Public DomainIn an episode ofABC's "Four Corners"this week, the use of spinal cord stimula

Updated on:April 28,2024

Pathway discovered that prevents buildup of Alzheimer's protein

by St. Jude Children's Research HospitalFirst author Bradlee Heckmann, Ph.D. (right), a postdoctoral fellow in Doug Green's (left) laboratory at St. Jude, led research that identified the

Updated on: May 28,2024

Pathway discovered that prevents buildup of Alzheimer's protein

by St. Jude Children's Research HospitalFirst author Bradlee Heckmann, Ph.D. (right), a postdoctoral fellow in Doug Green's (left) laboratory at St. Jude, led research that identified the

Updated on:May 28,2024

Visualizing core pathologies of Parkinson's disease and related disorders in live patients

by The National Institutes for Quantum Science and TechnologyResearchers from Japan developed a novel tracer compound that binds to α-synuclein aggregates, making them easy to detect in PET scans and

Updated on: July 08,2024

Visualizing core pathologies of Parkinson's disease and related disorders in live patients

by The National Institutes for Quantum Science and TechnologyResearchers from Japan developed a novel tracer compound that binds to α-synuclein aggregates, making them easy to detect in PET scans and

Updated on:July 08,2024

Jalisco mutation, rare strain of Alzheimer's affecting people in their 40s

by Ron Mackovich,University of Southern CaliforniaMaria Barocio, 45, who has early-onset Alzheimer’s, walks with her doctor, Freddi Segal-Gidan, at the Rancho Los Amigos National Rehabilitation

Updated on: June 05,2024

Jalisco mutation, rare strain of Alzheimer's affecting people in their 40s

by Ron Mackovich,University of Southern CaliforniaMaria Barocio, 45, who has early-onset Alzheimer’s, walks with her doctor, Freddi Segal-Gidan, at the Rancho Los Amigos National Rehabilitation

Updated on:June 05,2024

Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aβ oligomers

by Bar-Ilan University(A) Potential influence of azaGly residue on hydrogen-bonding of cyclic D,L-α-hexapeptide nanotubes which share common cross β-sheet structures with (B) Aβ. For clarity, all

Updated on: April 25,2024

Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aβ oligomers

by Bar-Ilan University(A) Potential influence of azaGly residue on hydrogen-bonding of cyclic D,L-α-hexapeptide nanotubes which share common cross β-sheet structures with (B) Aβ. For clarity, all

Updated on:April 25,2024

Research sheds light on why brain implants lose functionality

byUniversity of GalwayNeuroelectrode micromotion generates oscillatory fluid flow shear stress as determined by the peri-electrode void volume and fluid viscosity. A) Schematic of the model conf

Updated on: January 02,2024

Research sheds light on why brain implants lose functionality

byUniversity of GalwayNeuroelectrode micromotion generates oscillatory fluid flow shear stress as determined by the peri-electrode void volume and fluid viscosity. A) Schematic of the model conf

Updated on:January 02,2024

Study highlights the key role of the prefrontal cortex in regulating REM sleep

by Ingrid Fadelli , Medical XpressOptogenetic activation of mPFC Pyr neurons triggers REM sleep.a, Top: schematic of optogenetic activation of mPFC Pyr neurons. Bottom: expression of AAV-CaMKII-

Updated on: January 12,2024

Study highlights the key role of the prefrontal cortex in regulating REM sleep

by Ingrid Fadelli , Medical XpressOptogenetic activation of mPFC Pyr neurons triggers REM sleep.a, Top: schematic of optogenetic activation of mPFC Pyr neurons. Bottom: expression of AAV-CaMKII-

Updated on:January 12,2024

Novel blood test identifies biomarkers in patients with Alzheimer's disease

by Mike Addelman,University of ManchesterCredit: Pixabay/CC0 Public DomainEarly results from PharmaKure, a pharmaceutical company spun out from The University of Manchester, shows a novel whole

Updated on: January 05,2024

Novel blood test identifies biomarkers in patients with Alzheimer's disease

by Mike Addelman,University of ManchesterCredit: Pixabay/CC0 Public DomainEarly results from PharmaKure, a pharmaceutical company spun out from The University of Manchester, shows a novel whole

Updated on:January 05,2024

Gram-negative bacteria may influence Alzheimer's disease pathology

by UC DavisDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have found higher levels of Gram-negative bacteria antige

Updated on: June 04,2024

Gram-negative bacteria may influence Alzheimer's disease pathology

by UC DavisDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have found higher levels of Gram-negative bacteria antige

Updated on:June 04,2024

Brains with compromised 'trust settings' a warning sign of lurking depression

byHiroshima UniversityCredit: Andrea Piacquadio/PexelsJust as computer devices acting differently can hint at the possibility of malware lurking in the background, changes in brain patterns that

Updated on: January 21,2024

Brains with compromised 'trust settings' a warning sign of lurking depression

byHiroshima UniversityCredit: Andrea Piacquadio/PexelsJust as computer devices acting differently can hint at the possibility of malware lurking in the background, changes in brain patterns that

Updated on:January 21,2024