New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on: May 14,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Updated on:May 14,2024

A potential agent for treating preeclampsia

by Max Delbrück Center for Molecular MedicineThis image helps researchers analyze, among other things, the spiral arteries in order to gain insights into fetal nutrition. Credit: Nadine Haase, MD

Updated on: May 11,2024

A potential agent for treating preeclampsia

by Max Delbrück Center for Molecular MedicineThis image helps researchers analyze, among other things, the spiral arteries in order to gain insights into fetal nutrition. Credit: Nadine Haase, MD

Updated on:May 11,2024

Researchers identify 10 pesticides toxic to neurons involved in Parkinson's

by University of California, Los AngelesDescription of agricultural pesticide use in the study area, including geography of applications, number of unique active ingredients applied by year, tota

Updated on: June 11,2024

Researchers identify 10 pesticides toxic to neurons involved in Parkinson's

by University of California, Los AngelesDescription of agricultural pesticide use in the study area, including geography of applications, number of unique active ingredients applied by year, tota

Updated on:June 11,2024

Brains have a remarkable ability to rewire themselves following injury, concussion specialist explains

by Hilary A. Diefenbach,The ConversationCredit: Unsplash/CC0 Public DomainHigh-profile sports like football and soccer have brought greater attention in recent years to concussions—the mildest f

Updated on: January 10,2024

Brains have a remarkable ability to rewire themselves following injury, concussion specialist explains

by Hilary A. Diefenbach,The ConversationCredit: Unsplash/CC0 Public DomainHigh-profile sports like football and soccer have brought greater attention in recent years to concussions—the mildest f

Updated on:January 10,2024

How the gut sends signals to the brain: Scientists define five types of colon neurons

by Harvard Medical SchoolAn image of the colon wall showing different types of sensory neurons labeled with fluorescent dyes. Neurons that signal from the colon to the brain (green) become active

Updated on: February 05,2024

How the gut sends signals to the brain: Scientists define five types of colon neurons

by Harvard Medical SchoolAn image of the colon wall showing different types of sensory neurons labeled with fluorescent dyes. Neurons that signal from the colon to the brain (green) become active

Updated on:February 05,2024

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on: February 21,2024

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on:February 21,2024

Can a single brain region encode familiarity and recollection?

by Columbia UniversityGeometric arrangement for the coding of two animals' identities (N1 and N2) in different positions (left and right). Credit: Fusi Lab / Columbia Zuckerman InstituteThe h

Updated on: June 26,2024

Can a single brain region encode familiarity and recollection?

by Columbia UniversityGeometric arrangement for the coding of two animals' identities (N1 and N2) in different positions (left and right). Credit: Fusi Lab / Columbia Zuckerman InstituteThe h

Updated on:June 26,2024

How the brain learns to deal with surprises

byUniversity of BaselCredit: Pixabay/CC0 Public DomainFor children, the world is full of surprises. Adults, on the other hand, are much more difficult to surprise. And there are complex processe

Updated on: January 09,2024

How the brain learns to deal with surprises

byUniversity of BaselCredit: Pixabay/CC0 Public DomainFor children, the world is full of surprises. Adults, on the other hand, are much more difficult to surprise. And there are complex processe

Updated on:January 09,2024

Poor cognitive performance predicts impairment in activities of daily living years later

by University of California - San DiegoCredit: CC0 Public DomainSubtle differences in cognition may help identify individuals at risk for becoming dependent years later upon others to complete da

Updated on: June 24,2024

Poor cognitive performance predicts impairment in activities of daily living years later

by University of California - San DiegoCredit: CC0 Public DomainSubtle differences in cognition may help identify individuals at risk for becoming dependent years later upon others to complete da

Updated on:June 24,2024

Low doses of radiation may improve quality of life for those with severe Alzheimer's

by Baycrest Centre for Geriatric CareCredit: Pixabay/CC0 Public DomainIndividuals living with severe Alzheimer's disease showed remarkable improvements in behavior and cognition within days o

Updated on: May 22,2024

Low doses of radiation may improve quality of life for those with severe Alzheimer's

by Baycrest Centre for Geriatric CareCredit: Pixabay/CC0 Public DomainIndividuals living with severe Alzheimer's disease showed remarkable improvements in behavior and cognition within days o

Updated on:May 22,2024

Ultrasound enables gene delivery throughout the brain

byRice UniversityCredit: CC0 Public DomainRice University researchers tested the safety and feasibility of gene delivery to multiple brain regions using a noninvasive, ultrasound-based technique

Updated on: January 07,2024

Ultrasound enables gene delivery throughout the brain

byRice UniversityCredit: CC0 Public DomainRice University researchers tested the safety and feasibility of gene delivery to multiple brain regions using a noninvasive, ultrasound-based technique

Updated on:January 07,2024

Restoring 'chaperone' protein may prevent plaque build-up in Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaDAXX (red color at top) prevents the aggregation of mutant p53 protein associated with cancers (dark green color at bottom) in cell

Updated on: June 11,2024

Restoring 'chaperone' protein may prevent plaque build-up in Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaDAXX (red color at top) prevents the aggregation of mutant p53 protein associated with cancers (dark green color at bottom) in cell

Updated on:June 11,2024