First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024

A&E attendance for people with dementia is common and increasing

by King's College LondonCredit: CC0 Public DomainA new paper published today in the journalAlzheimer's & Dementia: The Journal of the Alzheimer's Associationfound that

Updated on: May 09,2024

A&E attendance for people with dementia is common and increasing

by King's College LondonCredit: CC0 Public DomainA new paper published today in the journalAlzheimer's & Dementia: The Journal of the Alzheimer's Associationfound that

Updated on:May 09,2024

Chemical clears Alzheimer's protein and restores memory in mice

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A research team in Korea has tested a chemical in mice genetically alt

Updated on: February 27,2024

Chemical clears Alzheimer's protein and restores memory in mice

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A research team in Korea has tested a chemical in mice genetically alt

Updated on:February 27,2024

Microscopic blood vessel disease in the brain's white matter associated with worse cognition in Alzheimer's

by Medical College of Georgia at Augusta UniversityDr. Zsolt Bagi with coauthors Katie Anne Fopiano, AU graduate student, and Dr. Yanna Tian, who just earned her graduate degree from AU and has s

Updated on: April 20,2024

Microscopic blood vessel disease in the brain's white matter associated with worse cognition in Alzheimer's

by Medical College of Georgia at Augusta UniversityDr. Zsolt Bagi with coauthors Katie Anne Fopiano, AU graduate student, and Dr. Yanna Tian, who just earned her graduate degree from AU and has s

Updated on:April 20,2024

Alzheimer's brain barrier damage theory could pave way for new treatments

by University of ReadingCredit: Pixabay/CC0 Public DomainAlzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brai

Updated on: April 07,2024

Alzheimer's brain barrier damage theory could pave way for new treatments

by University of ReadingCredit: Pixabay/CC0 Public DomainAlzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brai

Updated on:April 07,2024

Dementia risk scores have high error rates

by Lori SolomonCurrent dementia risk scores have high error rates and limited clinical utility for estimating 10-year risk, according to a study published online June 13 inJAMA Network Open.Mika

Updated on: May 06,2024

Dementia risk scores have high error rates

by Lori SolomonCurrent dementia risk scores have high error rates and limited clinical utility for estimating 10-year risk, according to a study published online June 13 inJAMA Network Open.Mika

Updated on:May 06,2024

Study suggests that attention networks support changes in cortical organization and cognition during childhood

by Ingrid Fadelli , Medical XpressVentral attention network areas demonstrate high population-level degree centrality but pronounced functional changes across development. Credit:Nature Neurosci

Updated on: September 23,2024

Study suggests that attention networks support changes in cortical organization and cognition during childhood

by Ingrid Fadelli , Medical XpressVentral attention network areas demonstrate high population-level degree centrality but pronounced functional changes across development. Credit:Nature Neurosci

Updated on:September 23,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on: April 01,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on:April 01,2024

How blocking a neural receptor responsible for addiction could reduce alcohol use

by The Scripps Research InstituteTime course of alcohol self-administration acquisition across 21 training sessions and escalation of drinking during week 6 of CIE vapor exposure. (A) Male and fe

Updated on: March 30,2024

How blocking a neural receptor responsible for addiction could reduce alcohol use

by The Scripps Research InstituteTime course of alcohol self-administration acquisition across 21 training sessions and escalation of drinking during week 6 of CIE vapor exposure. (A) Male and fe

Updated on:March 30,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024

Getting the temperature just right helps people with dementia stay cool

by Paul Cooper, Federico Tartarini And Richard Fleming,The ConversationDr Federico Tartarini (right) led the study that found that indoor temperatures in aged care centres have a dramatic impact

Updated on: April 29,2024

Getting the temperature just right helps people with dementia stay cool

by Paul Cooper, Federico Tartarini And Richard Fleming,The ConversationDr Federico Tartarini (right) led the study that found that indoor temperatures in aged care centres have a dramatic impact

Updated on:April 29,2024

Research suggests myelin fatty acid metabolism could serve as an energy reserve for the central nervous system

by Ingrid Fadelli , Medical XpressElectron microscopy image of optic nerve myelin. Credit: Wiebke Moebius, MPI Goettingen.The brains of mammals expend a significant amount of energy in the form of ade

Updated on: October 18,2024

Research suggests myelin fatty acid metabolism could serve as an energy reserve for the central nervous system

by Ingrid Fadelli , Medical XpressElectron microscopy image of optic nerve myelin. Credit: Wiebke Moebius, MPI Goettingen.The brains of mammals expend a significant amount of energy in the form of ade

Updated on:October 18,2024