Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on: May 22,2024 8

Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on:May 22,2024 8

Electronic health records help study drug-effectiveness in Alzheimer's disease

by Case Western Reserve UniversityCredit: CC0 Public DomainResearchers have harnessed the power of electronic health records to gain insight in the potential of inflammation-controlling medicatio

Updated on: May 22,2024 7

Electronic health records help study drug-effectiveness in Alzheimer's disease

by Case Western Reserve UniversityCredit: CC0 Public DomainResearchers have harnessed the power of electronic health records to gain insight in the potential of inflammation-controlling medicatio

Updated on:May 22,2024 7

Amyloid is a less accurate marker for measuring severity, progression of Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaPET imaging using the radiotracers FDG and florbetapir to quantify cognitive decline in patients with Alzheimer’s disease (AD), mil

Updated on: May 22,2024 3

Amyloid is a less accurate marker for measuring severity, progression of Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaPET imaging using the radiotracers FDG and florbetapir to quantify cognitive decline in patients with Alzheimer’s disease (AD), mil

Updated on:May 22,2024 3

Shorter telomeres point to increased Alzheimer's risk

by Kim Krieger,University of ConnecticutHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShort telomeres in midlife are associated with a higher risk of develo

Updated on: May 22,2024 7

Shorter telomeres point to increased Alzheimer's risk

by Kim Krieger,University of ConnecticutHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShort telomeres in midlife are associated with a higher risk of develo

Updated on:May 22,2024 7

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on: May 22,2024 4

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on:May 22,2024 4

Anticoagulants fail to prevent unexplained strokes, clinical trial finds

by Columbia University Irving Medical CenterVisual Abstract.Apixaban to Prevent Recurrence After Cryptogenic Stroke in Patients With Atrial Cardiopathy. Credit:JAMA, (2024). doi:10.10

Updated on: May 21,2024 8

Anticoagulants fail to prevent unexplained strokes, clinical trial finds

by Columbia University Irving Medical CenterVisual Abstract.Apixaban to Prevent Recurrence After Cryptogenic Stroke in Patients With Atrial Cardiopathy. Credit:JAMA, (2024). doi:10.10

Updated on:May 21,2024 8

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on: May 21,2024 4

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on:May 21,2024 4

Use of TNF alpha inhibitors in Crohn's disease associated with higher risk of MS

by Hillary Smith,University of KentuckyDr. Jay Avasarala, professor of neurology and director of UK’s Multiple Sclerosis Clinic, and co-authors, conducted a retrospective study in which they eva

Updated on: May 21,2024 8

Use of TNF alpha inhibitors in Crohn's disease associated with higher risk of MS

by Hillary Smith,University of KentuckyDr. Jay Avasarala, professor of neurology and director of UK’s Multiple Sclerosis Clinic, and co-authors, conducted a retrospective study in which they eva

Updated on:May 21,2024 8

Using prebiotics to help treat Parkinson's disease

by Ariana Baldassano,Rush University Medical CenterTen days of the prebiotic intervention had effects on biological outcomes. Credit:Nature Communications(2023). DOI: 10.1038/s41467-

Updated on: May 21,2024 7

Using prebiotics to help treat Parkinson's disease

by Ariana Baldassano,Rush University Medical CenterTen days of the prebiotic intervention had effects on biological outcomes. Credit:Nature Communications(2023). DOI: 10.1038/s41467-

Updated on:May 21,2024 7

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024 3

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024 3

Mediterranean diet associated with decreased risk of dementia

by Newcastle UniversityCredit: CC0 Public DomainEating a traditional Mediterranean-type diet—rich in foods such as seafood, fruit, and nuts—may help reduce the risk of dementia by almost a quarte

Updated on: May 20,2024 8

Mediterranean diet associated with decreased risk of dementia

by Newcastle UniversityCredit: CC0 Public DomainEating a traditional Mediterranean-type diet—rich in foods such as seafood, fruit, and nuts—may help reduce the risk of dementia by almost a quarte

Updated on:May 20,2024 8

Could a Mediterranean diet and exercise reduce dementia risk?

by University of East AngliaCredit: CC0 Public DomainResearchers at the University of East Anglia (UEA) are launching a new study to see whether eating a Mediterranean-style diet and being more a

Updated on: May 20,2024 7

Could a Mediterranean diet and exercise reduce dementia risk?

by University of East AngliaCredit: CC0 Public DomainResearchers at the University of East Anglia (UEA) are launching a new study to see whether eating a Mediterranean-style diet and being more a

Updated on:May 20,2024 7