How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on: March 07,2024 12

How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on:March 07,2024 12

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism

Updated on: March 27,2024 0

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism

Updated on:March 27,2024 0

Risankizumab safe, effective at 52 weeks for psoriatic arthritis

by Lori SolomonRisankizumab provides long-term benefits in patients with psoriatic arthritis (PsA) who have not achieved adequate response to previous therapies, according to a study recently publishe

Updated on: June 01,2024 7

Risankizumab safe, effective at 52 weeks for psoriatic arthritis

by Lori SolomonRisankizumab provides long-term benefits in patients with psoriatic arthritis (PsA) who have not achieved adequate response to previous therapies, according to a study recently publishe

Updated on:June 01,2024 7

Some cases of long COVID-19 may be caused by an abnormally suppressed immune system

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainA UCLA-led team of researchers studying the effect of the monoclonal antibody Leronlimab on long COVID-19 may have found

Updated on: May 05,2024 12

Some cases of long COVID-19 may be caused by an abnormally suppressed immune system

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainA UCLA-led team of researchers studying the effect of the monoclonal antibody Leronlimab on long COVID-19 may have found

Updated on:May 05,2024 12

CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

by University of PennsylvaniaCDH17 CARTs attack tumor but spare normal tissue. Credit: Penn MedicineChimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and l

Updated on: April 09,2024 16

CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

by University of PennsylvaniaCDH17 CARTs attack tumor but spare normal tissue. Credit: Penn MedicineChimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and l

Updated on:April 09,2024 16

Patients with rheumatoid arthritis have increased anxiety during pandemic

For patients with rheumatoid arthritis (RA), anxiety increased during the COVID-19 pandemic, as did suspected depression, according to a letter to the editor published online Jan. 27 inRheumatol

Updated on: June 28,2024 8

Patients with rheumatoid arthritis have increased anxiety during pandemic

For patients with rheumatoid arthritis (RA), anxiety increased during the COVID-19 pandemic, as did suspected depression, according to a letter to the editor published online Jan. 27 inRheumatol

Updated on:June 28,2024 8

Prevalence of gout increases with increasing BMI

Having an increased body mass index correlates with increased prevalence of gout in adults, according to study published online July 6 inArthritis Care & Research.(HealthDay) -- Having an in

Updated on: April 08,2024 17

Prevalence of gout increases with increasing BMI

Having an increased body mass index correlates with increased prevalence of gout in adults, according to study published online July 6 inArthritis Care & Research.(HealthDay) -- Having an in

Updated on:April 08,2024 17

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on: April 08,2024 19

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on:April 08,2024 19

Dupilumab cuts exacerbations in late-onset asthma

(HealthDay)—Dupilumab is associated with significantly reduced severe exacerbation rates in patients with late-onset asthma with or without fixed airway obstruction, according to a study presented at

Updated on: April 15,2024 18

Dupilumab cuts exacerbations in late-onset asthma

(HealthDay)—Dupilumab is associated with significantly reduced severe exacerbation rates in patients with late-onset asthma with or without fixed airway obstruction, according to a study presented at

Updated on:April 15,2024 18

SARS-CoV-2 disrupts timing of immune response

by Charité - Universitätsmedizin BerlinAssay to detect the biochemical messenger TGFβ (COVID-19 research). Credit: Charité | Arne SattlerOnce an infection is under control, the body normally uses

Updated on: April 22,2024 17

SARS-CoV-2 disrupts timing of immune response

by Charité - Universitätsmedizin BerlinAssay to detect the biochemical messenger TGFβ (COVID-19 research). Credit: Charité | Arne SattlerOnce an infection is under control, the body normally uses

Updated on:April 22,2024 17

New 3-D imaging analysis technique could lead to improved arthritis treatment

by University of CambridgeJoint space in hip, knee and ankle joints as analyzed by the JSM algorithm. Credit: Tom TurmezeiAn algorithm to monitor the joints of patients with arthritis, which coul

Updated on: May 29,2024 6

New 3-D imaging analysis technique could lead to improved arthritis treatment

by University of CambridgeJoint space in hip, knee and ankle joints as analyzed by the JSM algorithm. Credit: Tom TurmezeiAn algorithm to monitor the joints of patients with arthritis, which coul

Updated on:May 29,2024 6

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on: March 24,2024 16

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on:March 24,2024 16