A bacterial toxin turning cells into swiss cheese

by Kanazawa UniversityResearchers from Kanazawa University developed a novel tool to study how the innate immune system fights bacterial toxins. They purified the pore-forming toxin Monalysin fro

Updated on: May 05,2024

A bacterial toxin turning cells into swiss cheese

by Kanazawa UniversityResearchers from Kanazawa University developed a novel tool to study how the innate immune system fights bacterial toxins. They purified the pore-forming toxin Monalysin fro

Updated on:May 05,2024

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on: March 24,2024

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on:March 24,2024

HDL composition may help predict health risks and design therapeutics

by Pat Bailey,UC DavisNutrition researcher Angela Zivkovic and colleagues have found that the amounts and specific structure of complex sugars called glycans can powerfully influence the body’s

Updated on: April 16,2024

HDL composition may help predict health risks and design therapeutics

by Pat Bailey,UC DavisNutrition researcher Angela Zivkovic and colleagues have found that the amounts and specific structure of complex sugars called glycans can powerfully influence the body’s

Updated on:April 16,2024

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on: June 26,2024

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on:June 26,2024

T-cell dysfunction increases cancer risk in obese populations, researchers say

bySaint Louis UniversityCD8+T cell dysfunction in the obese tumor microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-47359-5Researchers at Saint Loui

Updated on: November 24,2024

T-cell dysfunction increases cancer risk in obese populations, researchers say

bySaint Louis UniversityCD8+T cell dysfunction in the obese tumor microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-47359-5Researchers at Saint Loui

Updated on:November 24,2024

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3

Updated on: March 28,2024

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3

Updated on:March 28,2024

FDA approves first interchangeable biosimilar for inflammatory diseases

(HealthDay)—The first interchangeable biosimilar product to Humira (adalimumab) was approved by the U.S. Food and Drug Administration on Oct. 15, the agency announced Monday.Cyltezo (adalimumab-adbm),

Updated on: June 17,2024

FDA approves first interchangeable biosimilar for inflammatory diseases

(HealthDay)—The first interchangeable biosimilar product to Humira (adalimumab) was approved by the U.S. Food and Drug Administration on Oct. 15, the agency announced Monday.Cyltezo (adalimumab-adbm),

Updated on:June 17,2024

Severe reaction to pneumococcal vaccines in patients with CAPS

(HealthDay)—Pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with cryopyrin-associated periodic syndromes (CAPS), according to a study published in the F

Updated on: April 17,2024

Severe reaction to pneumococcal vaccines in patients with CAPS

(HealthDay)—Pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with cryopyrin-associated periodic syndromes (CAPS), according to a study published in the F

Updated on:April 17,2024

Adherence to mediterranean diet not linked to risk of RA

(HealthDay)—Adherence to a Mediterranean diet is not associated with incidence of rheumatoid arthritis (RA) in U.S. women, according to a study published in the May issue ofArthritis Care &

Updated on: April 08,2024

Adherence to mediterranean diet not linked to risk of RA

(HealthDay)—Adherence to a Mediterranean diet is not associated with incidence of rheumatoid arthritis (RA) in U.S. women, according to a study published in the May issue ofArthritis Care &

Updated on:April 08,2024

Specialist nurses as good as doctors in managing rheumatoid arthritis patients

by University of LeedsPatients attending clinical nurse specialist clinics do not get inferior treatment to that offered by consultant rheumatologists, the results of a major new clinical trial h

Updated on: March 24,2024

Specialist nurses as good as doctors in managing rheumatoid arthritis patients

by University of LeedsPatients attending clinical nurse specialist clinics do not get inferior treatment to that offered by consultant rheumatologists, the results of a major new clinical trial h

Updated on:March 24,2024

Researchers discover key metabolic process responsible for rapid immune responses

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) identified a key metabolite in cells that helps direct i

Updated on: March 19,2024

Researchers discover key metabolic process responsible for rapid immune responses

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) identified a key metabolite in cells that helps direct i

Updated on:March 19,2024

First-in-human trial with CAR macrophages shows promise targeting solid tumors

by Caren Begun,University of PennsylvaniaCredit: Pixabay/CC0 Public DomainPreliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability a

Updated on: April 09,2024

First-in-human trial with CAR macrophages shows promise targeting solid tumors

by Caren Begun,University of PennsylvaniaCredit: Pixabay/CC0 Public DomainPreliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability a

Updated on:April 09,2024