An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on: March 07,2024

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on:March 07,2024

A new approach to study autoimmune diseases

by Indiana Biosciences Research InstituteVenn diagrams of risk genes expressed in the target tissues of the fourautoimmune diseases (type 1 diabetes, systemic lupus erythematosus, multiple sclerosis,

Updated on: March 25,2024

A new approach to study autoimmune diseases

by Indiana Biosciences Research InstituteVenn diagrams of risk genes expressed in the target tissues of the fourautoimmune diseases (type 1 diabetes, systemic lupus erythematosus, multiple sclerosis,

Updated on:March 25,2024

Promising target for CAR T cells helps cancer trick the immune system

by St. Jude Children's Research HospitalGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101297Findings from St. Jude Children's Research Hospi

Updated on: April 09,2024

Promising target for CAR T cells helps cancer trick the immune system

by St. Jude Children's Research HospitalGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101297Findings from St. Jude Children's Research Hospi

Updated on:April 09,2024

Study investigates rates of adverse events for common rheumatoid arthritis drug

by Brigham and Women's HospitalCredit: CC0 Public DomainMethotrexate is a common drug with a long history; for the past 40 years, it's been used to treat a range of diseases. Today it is

Updated on: June 17,2024

Study investigates rates of adverse events for common rheumatoid arthritis drug

by Brigham and Women's HospitalCredit: CC0 Public DomainMethotrexate is a common drug with a long history; for the past 40 years, it's been used to treat a range of diseases. Today it is

Updated on:June 17,2024

Researchers discover potential new approach to treating psoriatic joint inflammation

by UC DavisCredit: CC0 Public DomainAn international team of researchers, led by UC Davis Health, has developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory

Updated on: June 17,2024

Researchers discover potential new approach to treating psoriatic joint inflammation

by UC DavisCredit: CC0 Public DomainAn international team of researchers, led by UC Davis Health, has developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory

Updated on:June 17,2024

Novel study identifies key molecular players in rheumatoid arthritis

by University of California - San DiegoAn x-ray depicts a hand fully affected by rheumatoid arthritis, which is characterized by swollen, painful joints, most commonly involving the wrists and ha

Updated on: June 15,2024

Novel study identifies key molecular players in rheumatoid arthritis

by University of California - San DiegoAn x-ray depicts a hand fully affected by rheumatoid arthritis, which is characterized by swollen, painful joints, most commonly involving the wrists and ha

Updated on:June 15,2024

Points to consider when using interferon assays

by European Alliance of Associations for Rheumatology (EULAR)Credit: Pixabay/CC0 Public DomainInterferons are type of protein called a cytokine. They have important roles in the immune system. Interfe

Updated on: May 26,2024

Points to consider when using interferon assays

by European Alliance of Associations for Rheumatology (EULAR)Credit: Pixabay/CC0 Public DomainInterferons are type of protein called a cytokine. They have important roles in the immune system. Interfe

Updated on:May 26,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on: April 08,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on:April 08,2024

Over 40 genetic links to rheumatoid arthritis discovered

by The Mount Sinai HospitalThe results of the largest international study to date into the genetic basis of rheumatoid arthritis, published in the journal Nature, shed light on the biology of the

Updated on: March 24,2024

Over 40 genetic links to rheumatoid arthritis discovered

by The Mount Sinai HospitalThe results of the largest international study to date into the genetic basis of rheumatoid arthritis, published in the journal Nature, shed light on the biology of the

Updated on:March 24,2024

Building tolerance helps kids with wheat allergy

(HealthDay)—Giving trace amounts of wheat to children with wheat allergy shows promise in treating the allergy, according to new research.The researchers started with 46 wheat-allergicchildren,

Updated on: April 08,2024

Building tolerance helps kids with wheat allergy

(HealthDay)—Giving trace amounts of wheat to children with wheat allergy shows promise in treating the allergy, according to new research.The researchers started with 46 wheat-allergicchildren,

Updated on:April 08,2024

Pretreatment with TNF inhibitors may improve outcomes of combination cancer immunotherapy

by Universidad de NavarraStudy proposes a new therapeutic approach against cancer that dissociates efficacy and toxicity in the use of combined immunotherapy in animal models. This clinical strat

Updated on: May 08,2024

Pretreatment with TNF inhibitors may improve outcomes of combination cancer immunotherapy

by Universidad de NavarraStudy proposes a new therapeutic approach against cancer that dissociates efficacy and toxicity in the use of combined immunotherapy in animal models. This clinical strat

Updated on:May 08,2024

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on: April 16,2024

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on:April 16,2024