Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Updated on: September 18,2024

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Updated on:September 18,2024

COVID-19 : Measuring viral RNA to predict which patients will die

by University of MontrealColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the NIAI

Updated on: April 10,2024

COVID-19 : Measuring viral RNA to predict which patients will die

by University of MontrealColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the NIAI

Updated on:April 10,2024

The anterior chamber of the eye as a servant to medical research

by Karolinska InstitutetCredit: B Henrique, PixabayTo mechanistically understand what happens in the living body under physiological and pathological conditions, requires a non-invasive high spat

Updated on: March 07,2024

The anterior chamber of the eye as a servant to medical research

by Karolinska InstitutetCredit: B Henrique, PixabayTo mechanistically understand what happens in the living body under physiological and pathological conditions, requires a non-invasive high spat

Updated on:March 07,2024

A possible mechanism of lymphocyte deficiency in patients with COVID-19

by Russian Foundation for Basic ResearchCreative rendition of SARS-CoV-2 particles (not to scale). Credit: National Institute of Allergy and Infectious Diseases, NIHScientists from RUDN, National Medi

Updated on: April 10,2024

A possible mechanism of lymphocyte deficiency in patients with COVID-19

by Russian Foundation for Basic ResearchCreative rendition of SARS-CoV-2 particles (not to scale). Credit: National Institute of Allergy and Infectious Diseases, NIHScientists from RUDN, National Medi

Updated on:April 10,2024

Evolutionary origin of mysterious immune system molecule in humans revealed

by Ashley WennersHerron,Pennsylvania State UniversityThe Joining chain shares three characteristics with the CXCL chemokine genes, including the same number of exons, which encode the protein, a

Updated on: April 22,2024

Evolutionary origin of mysterious immune system molecule in humans revealed

by Ashley WennersHerron,Pennsylvania State UniversityThe Joining chain shares three characteristics with the CXCL chemokine genes, including the same number of exons, which encode the protein, a

Updated on:April 22,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on: May 05,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on:May 05,2024

COVID-19 causes some patients' immune systems to attack their own bodies, which may contribute to severe illness

by Matthew Woodruff,The ConversationCredit: Pixabay/CC0 Public DomainAround the world, immunologists who retooled their labs to join the fight against SARS-CoV-2 are furiously trying to explain

Updated on: April 10,2024

COVID-19 causes some patients' immune systems to attack their own bodies, which may contribute to severe illness

by Matthew Woodruff,The ConversationCredit: Pixabay/CC0 Public DomainAround the world, immunologists who retooled their labs to join the fight against SARS-CoV-2 are furiously trying to explain

Updated on:April 10,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on: April 20,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on:April 20,2024

Among allergic conditions, food allergy found to have highest risk of developing eosinophilic esophagitis

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainEosinophilic esophagitis (EoE), a disorder of the esophagus, is increasingly recognized as a major cause of

Updated on: November 01,2024

Among allergic conditions, food allergy found to have highest risk of developing eosinophilic esophagitis

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainEosinophilic esophagitis (EoE), a disorder of the esophagus, is increasingly recognized as a major cause of

Updated on:November 01,2024

World's first CAR-T cell therapy for a child with lupus

byFriedrich–Alexander University Erlangen–NurnbergThe medical team and their patient (left to right): Dr. Tobias Krickau, Dr. Nora Naumann-Bartsch, Patientin Uresa A., Prof. Dr. Markus Metzler,

Updated on: July 09,2024

World's first CAR-T cell therapy for a child with lupus

byFriedrich–Alexander University Erlangen–NurnbergThe medical team and their patient (left to right): Dr. Tobias Krickau, Dr. Nora Naumann-Bartsch, Patientin Uresa A., Prof. Dr. Markus Metzler,

Updated on:July 09,2024

How do MAIT cells identify and attack foreign invaders?

byUniversity of MelbourneCredit: CC0 Public DomainMelbourne researchers have identified what makes a specialised immune cell, known as mucosal-associated invariant T (MAIT), cells boost their nu

Updated on: April 20,2024

How do MAIT cells identify and attack foreign invaders?

byUniversity of MelbourneCredit: CC0 Public DomainMelbourne researchers have identified what makes a specialised immune cell, known as mucosal-associated invariant T (MAIT), cells boost their nu

Updated on:April 20,2024

Research into autoimmune liver condition suggests unique cell movements may drive disease

by University of BirminghamCD8+T cell internalization into BEC is a consistent event in PBC patients with ongoing disease. a) Representative fluorescence image of liver core biopsy, taken f

Updated on: March 07,2024

Research into autoimmune liver condition suggests unique cell movements may drive disease

by University of BirminghamCD8+T cell internalization into BEC is a consistent event in PBC patients with ongoing disease. a) Representative fluorescence image of liver core biopsy, taken f

Updated on:March 07,2024