An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on: March 30,2024

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on:March 30,2024

Moms with lupus more likely to have children with autism, study suggests

by Serena Gordon, Healthday ReporterBut overall risk is low, shouldn't influence parenting decisions, expert says.(HealthDay)—Women with lupus are twice as likely to have a child with autism compa

Updated on: March 24,2024

Moms with lupus more likely to have children with autism, study suggests

by Serena Gordon, Healthday ReporterBut overall risk is low, shouldn't influence parenting decisions, expert says.(HealthDay)—Women with lupus are twice as likely to have a child with autism compa

Updated on:March 24,2024

Researchers uncover new mode of action for HUMIRA in rheumatoid arthritis patients

by Rockefeller University PressIn the presence of adalimumab, TNF on the surface of a monocyte interacts with receptor molecules on the surface of two regulatory T cells, thereby promoting their

Updated on: March 24,2024

Researchers uncover new mode of action for HUMIRA in rheumatoid arthritis patients

by Rockefeller University PressIn the presence of adalimumab, TNF on the surface of a monocyte interacts with receptor molecules on the surface of two regulatory T cells, thereby promoting their

Updated on:March 24,2024

A plant-based compound that inhibits reactivation of the HIV viral reservoir, giving the immune system a break

by The Wistar InstituteOverview of HIV inhibitor screening strategy and identification of (–)-hopeaphenol. (A) Representative flow cytometry examples of HIV-GFP reporter expression in unstimulate

Updated on: May 05,2024

A plant-based compound that inhibits reactivation of the HIV viral reservoir, giving the immune system a break

by The Wistar InstituteOverview of HIV inhibitor screening strategy and identification of (–)-hopeaphenol. (A) Representative flow cytometry examples of HIV-GFP reporter expression in unstimulate

Updated on:May 05,2024

RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

Updated on: April 22,2024

RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

Updated on:April 22,2024

Flu vaccine cuts mortality in rheumatoid arthritis patients

(HealthDay)—Patients with rheumatoid arthritis (RA), particularly elderly patients, who receive the influenza vaccine have significantly lower morbidity and mortality, according to a study published i

Updated on: April 17,2024

Flu vaccine cuts mortality in rheumatoid arthritis patients

(HealthDay)—Patients with rheumatoid arthritis (RA), particularly elderly patients, who receive the influenza vaccine have significantly lower morbidity and mortality, according to a study published i

Updated on:April 17,2024

Study uncovers novel mechanisms behind food allergies

by Melissa Rohman,Northwestern UniversityCredit:Mucosal Immunology(2023). DOI: 10.1016/j.mucimm.2023.12.001A recent Northwestern Medicine study has shed light on the mechanisms of a

Updated on: March 19,2024

Study uncovers novel mechanisms behind food allergies

by Melissa Rohman,Northwestern UniversityCredit:Mucosal Immunology(2023). DOI: 10.1016/j.mucimm.2023.12.001A recent Northwestern Medicine study has shed light on the mechanisms of a

Updated on:March 19,2024

Scientists use blood test to track gene expression in the brain

by Kayt Sukel,Rice UniversityScan of mouse hippocampus and cortex, where the red signal derives from immunostaining for the synthetic marker developed by the Szablowski lab and the blue from the

Updated on: April 23,2024

Scientists use blood test to track gene expression in the brain

by Kayt Sukel,Rice UniversityScan of mouse hippocampus and cortex, where the red signal derives from immunostaining for the synthetic marker developed by the Szablowski lab and the blue from the

Updated on:April 23,2024

A near-fatal Valley Fever case opens doors to new treatment method

by Ryan Hatoum,University of California, Los AngelesAbraham Gonzalez-Martinez, who had a dangerous case of Valley Fever, at UCLA Mattel Children’s Hospital. Credit: University of California, Los

Updated on: May 08,2024

A near-fatal Valley Fever case opens doors to new treatment method

by Ryan Hatoum,University of California, Los AngelesAbraham Gonzalez-Martinez, who had a dangerous case of Valley Fever, at UCLA Mattel Children’s Hospital. Credit: University of California, Los

Updated on:May 08,2024

A small T cell switch with a big impact

by Julius-Maximilians-Universität WürzburgCredit: CC0 Public DomainT cells play a key role in the human immune system. They are capable of distinguishing diseased or foreign tissue from the body&

Updated on: May 07,2024

A small T cell switch with a big impact

by Julius-Maximilians-Universität WürzburgCredit: CC0 Public DomainT cells play a key role in the human immune system. They are capable of distinguishing diseased or foreign tissue from the body&

Updated on:May 07,2024

10 percent of US adults physically limited by arthritis, CDC reports

by Steven Reinberg, Healthday ReporterExperts say obesity epidemic has widened the pool of disabled.(HealthDay)—More than 50 million Americans have arthritis, and almost half of them can't perform

Updated on: March 24,2024

10 percent of US adults physically limited by arthritis, CDC reports

by Steven Reinberg, Healthday ReporterExperts say obesity epidemic has widened the pool of disabled.(HealthDay)—More than 50 million Americans have arthritis, and almost half of them can't perform

Updated on:March 24,2024

Consensus statement issued on management of foot, ankle gout

(HealthDay)—The American College of Foot and Ankle Surgeons and the American Association of Nurse Practitioners-Orthopedics Specialty Practice Group have issued a new joint clinical consensus statemen

Updated on: April 20,2024

Consensus statement issued on management of foot, ankle gout

(HealthDay)—The American College of Foot and Ankle Surgeons and the American Association of Nurse Practitioners-Orthopedics Specialty Practice Group have issued a new joint clinical consensus statemen

Updated on:April 20,2024