St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on: April 22,2024

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on:April 22,2024

New method is better able to map immune response and paves way for new treatments

byKarolinska InstitutetSpatial transcriptomics–based method to map B cell and T cell receptors.Targeted capture of antigen receptor sequences from spatial transcriptomics gene expression librari

Updated on: January 26,2024

New method is better able to map immune response and paves way for new treatments

byKarolinska InstitutetSpatial transcriptomics–based method to map B cell and T cell receptors.Targeted capture of antigen receptor sequences from spatial transcriptomics gene expression librari

Updated on:January 26,2024

Researchers identify new way to inhibit immune cells that drive allergic asthma

by Rockefeller University PressActivation of ILC2s causes inflammation in mouse lungs (left), but this is reduced by treatment with Yoda1 to stimulate Piezo1 channels (right). Credit:(2024)

Updated on: April 06,2024

Researchers identify new way to inhibit immune cells that drive allergic asthma

by Rockefeller University PressActivation of ILC2s causes inflammation in mouse lungs (left), but this is reduced by treatment with Yoda1 to stimulate Piezo1 channels (right). Credit:(2024)

Updated on:April 06,2024

S1P molecule regulates dendritic cell localization and vascular integrity in lymph nodes

by Osaka UniversityCredit: Osaka UniversityThe trafficking of white blood cells called lymphocytes is crucial for controlling our immune response. Maintaining the integrity of high endothelial ve

Updated on: April 22,2024

S1P molecule regulates dendritic cell localization and vascular integrity in lymph nodes

by Osaka UniversityCredit: Osaka UniversityThe trafficking of white blood cells called lymphocytes is crucial for controlling our immune response. Maintaining the integrity of high endothelial ve

Updated on:April 22,2024

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025

How RNA editing affects the immune system

by CU Anschutz Medical CampusCredit: CC0 Public DomainThree University of Colorado Cancer Center researchers are part of a team that recently published a paper offering new insight into how the i

Updated on: April 22,2024

How RNA editing affects the immune system

by CU Anschutz Medical CampusCredit: CC0 Public DomainThree University of Colorado Cancer Center researchers are part of a team that recently published a paper offering new insight into how the i

Updated on:April 22,2024

Researchers correlate rheumatoid arthritis and giant cell arteritis with solar cycles

by John Greenwald,Princeton Plasma Physics LaboratoryAcoronal mass ejection is hurled from the sun. Credit: NASAWhat began as a chat between husband and wife has evolved into an intriguing

Updated on: June 26,2024

Researchers correlate rheumatoid arthritis and giant cell arteritis with solar cycles

by John Greenwald,Princeton Plasma Physics LaboratoryAcoronal mass ejection is hurled from the sun. Credit: NASAWhat began as a chat between husband and wife has evolved into an intriguing

Updated on:June 26,2024

Filling data gaps: Gender equity in academic rheumatology

by European Alliance of Associations for Rheumatology, EULARTypical self-reported working hours in a week by role and gender, EULAR and EMEUNET members, 323 responses. The box and whisker chart shows

Updated on: June 01,2024

Filling data gaps: Gender equity in academic rheumatology

by European Alliance of Associations for Rheumatology, EULARTypical self-reported working hours in a week by role and gender, EULAR and EMEUNET members, 323 responses. The box and whisker chart shows

Updated on:June 01,2024

Hope for treating autoimmune diseases: Researchers explore diagnostic role of the systemic inflammation index

by Flinders UniversityCredit: Unsplash/CC0 Public DomainA routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of

Updated on: April 06,2024

Hope for treating autoimmune diseases: Researchers explore diagnostic role of the systemic inflammation index

by Flinders UniversityCredit: Unsplash/CC0 Public DomainA routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of

Updated on:April 06,2024

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on: April 22,2024

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on:April 22,2024

Psoriasis patients can get clearer skin with at-home treatment instead of at doctors' offices, study suggests

by Alex Gardner,Perelman School of Medicine at the University of PennsylvaniaCredit: Estzer Miller on PixabayFor decades, people with psoriasis have been treated in clinics with narrowband ultra

Updated on: October 28,2024

Psoriasis patients can get clearer skin with at-home treatment instead of at doctors' offices, study suggests

by Alex Gardner,Perelman School of Medicine at the University of PennsylvaniaCredit: Estzer Miller on PixabayFor decades, people with psoriasis have been treated in clinics with narrowband ultra

Updated on:October 28,2024

Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses

byUniversity of CambridgeBiochemist Professor Anne Willis and immunologist Dr James Thaventhiran at the MRC Toxicology Unit at the University of Cambridge led this work. Credit: Mike Thornton, S

Updated on: January 26,2024

Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses

byUniversity of CambridgeBiochemist Professor Anne Willis and immunologist Dr James Thaventhiran at the MRC Toxicology Unit at the University of Cambridge led this work. Credit: Mike Thornton, S

Updated on:January 26,2024