S1P molecule regulates dendritic cell localization and vascular integrity in lymph nodes

by Osaka UniversityCredit: Osaka UniversityThe trafficking of white blood cells called lymphocytes is crucial for controlling our immune response. Maintaining the integrity of high endothelial ve

Updated on: April 22,2024 16

S1P molecule regulates dendritic cell localization and vascular integrity in lymph nodes

by Osaka UniversityCredit: Osaka UniversityThe trafficking of white blood cells called lymphocytes is crucial for controlling our immune response. Maintaining the integrity of high endothelial ve

Updated on:April 22,2024 16

SIV shrugs off antibodies in vaccinated monkeys

by Emory UniversityNew research on monkeys vaccinated against HIV's relative SIV calls into question an idea that has driven AIDS vaccine work for years. The assumption: a protective vaccine

Updated on: April 22,2024 11

SIV shrugs off antibodies in vaccinated monkeys

by Emory UniversityNew research on monkeys vaccinated against HIV's relative SIV calls into question an idea that has driven AIDS vaccine work for years. The assumption: a protective vaccine

Updated on:April 22,2024 11

Initial SARS-CoV-2 vaccinations prime immune cells to respond to subsequent variants, study finds

by Perelman School of Medicine at the University of PennsylvaniaGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.02.017A new study from the Perelman School of Med

Updated on: March 19,2024 13

Initial SARS-CoV-2 vaccinations prime immune cells to respond to subsequent variants, study finds

by Perelman School of Medicine at the University of PennsylvaniaGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.02.017A new study from the Perelman School of Med

Updated on:March 19,2024 13

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on: March 30,2024 19

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on:March 30,2024 19

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on: March 07,2024 12

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on:March 07,2024 12

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on: April 22,2024 15

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on:April 22,2024 15

RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

Updated on: April 22,2024 14

RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

Updated on:April 22,2024 14

Review highlights the challenges and recent advances in targeted therapies for lupus nephritis

by Cactus CommunicationsSLE involves abnormal activation of both innate and adaptive immune responses, leading to systemic immune dysregulation and renal impairment. The complement system's dysfun

Updated on: January 26,2024 13

Review highlights the challenges and recent advances in targeted therapies for lupus nephritis

by Cactus CommunicationsSLE involves abnormal activation of both innate and adaptive immune responses, leading to systemic immune dysregulation and renal impairment. The complement system's dysfun

Updated on:January 26,2024 13

Running won't raise risk of knee arthritis, study says

In fact, it suggests running may even help prevent painful joint condition.(HealthDay)—Regular running doesn't seem to increase your chances of developing knee osteoarthritis, and it may even help

Updated on: April 08,2024 15

Running won't raise risk of knee arthritis, study says

In fact, it suggests running may even help prevent painful joint condition.(HealthDay)—Regular running doesn't seem to increase your chances of developing knee osteoarthritis, and it may even help

Updated on:April 08,2024 15

Causes of osteoarthritis mapped in new biobank

by Sanna Trygg,Lund University"What are the fundamental mechanical causes of osteoarthritis? And how can we slow or reverse its progression?" These are the questions asked by professor

Updated on: March 30,2024 19

Causes of osteoarthritis mapped in new biobank

by Sanna Trygg,Lund University"What are the fundamental mechanical causes of osteoarthritis? And how can we slow or reverse its progression?" These are the questions asked by professor

Updated on:March 30,2024 19

Groundbreaking study reveals clues to predict mortality in rare VEXAS syndrome

by American College of RheumatologyHematopoietic precursor cells: promyelocyte in the center, two metamyelocytes next to it and band cells from a bone marrow aspirate. Credit: Bobjgalindo/Wikiped

Updated on: May 23,2024 4

Groundbreaking study reveals clues to predict mortality in rare VEXAS syndrome

by American College of RheumatologyHematopoietic precursor cells: promyelocyte in the center, two metamyelocytes next to it and band cells from a bone marrow aspirate. Credit: Bobjgalindo/Wikiped

Updated on:May 23,2024 4

This gross mixture has big benefits for the study of bacteria

byUniversity of MichiganDetermining the bottleneck of infection forP. mirabilisduring UTI. (A–C) CBA/J mice were transurethrally inoculated with 107CFU. The inoculum contained

Updated on: January 25,2024 17

This gross mixture has big benefits for the study of bacteria

byUniversity of MichiganDetermining the bottleneck of infection forP. mirabilisduring UTI. (A–C) CBA/J mice were transurethrally inoculated with 107CFU. The inoculum contained

Updated on:January 25,2024 17