New findings on tuberculosis could change how we treat inflammatory disorders

by Katherine Fenz,Rockefeller UniversityCredit: Unsplash/CC0 Public DomainTuberculosis (TB) is a confounding scourge. It's the leading cause of death from infectious disease in the world, an

Updated on: September 03,2024 0

New findings on tuberculosis could change how we treat inflammatory disorders

by Katherine Fenz,Rockefeller UniversityCredit: Unsplash/CC0 Public DomainTuberculosis (TB) is a confounding scourge. It's the leading cause of death from infectious disease in the world, an

Updated on:September 03,2024 0

Skyrizi approved for psoriatic arthritis

(HealthDay)—The U.S. Food and Drug Administration has expanded the approval of Skyrizi (risankizumab-rzaa) to treatment of adults with active psoriatic arthritis, the manufacturer announced Friday.The

Updated on: May 26,2024 6

Skyrizi approved for psoriatic arthritis

(HealthDay)—The U.S. Food and Drug Administration has expanded the approval of Skyrizi (risankizumab-rzaa) to treatment of adults with active psoriatic arthritis, the manufacturer announced Friday.The

Updated on:May 26,2024 6

Holding mycophenolate mofetil for 10 days or more may improve COVID-19 vaccine response

by American College of RheumatologyAnti-spike antibody response following two dose SARS-CoV_2 vaccine dose in RMD, stratified by peri-vaccination mycophenolate hold duration. Credit: Increased Du

Updated on: May 13,2024 7

Holding mycophenolate mofetil for 10 days or more may improve COVID-19 vaccine response

by American College of RheumatologyAnti-spike antibody response following two dose SARS-CoV_2 vaccine dose in RMD, stratified by peri-vaccination mycophenolate hold duration. Credit: Increased Du

Updated on:May 13,2024 7

Osteoarthritis biomarker could help cut $23 billion health bill

by Candy Gibson,University of South AustraliaCredit: Pixabay/CC0 Public DomainUniversity of South Australia researchers are a step closer to finding a new biomarker for osteoarthritis, a painful

Updated on: May 13,2024 5

Osteoarthritis biomarker could help cut $23 billion health bill

by Candy Gibson,University of South AustraliaCredit: Pixabay/CC0 Public DomainUniversity of South Australia researchers are a step closer to finding a new biomarker for osteoarthritis, a painful

Updated on:May 13,2024 5

Exploring why some newborns develop severe infections

by Columbia University Irving Medical CenterGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.02.002Compared to adults, newborns are highly susceptible to infections and

Updated on: March 19,2024 13

Exploring why some newborns develop severe infections

by Columbia University Irving Medical CenterGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.02.002Compared to adults, newborns are highly susceptible to infections and

Updated on:March 19,2024 13

This gross mixture has big benefits for the study of bacteria

byUniversity of MichiganDetermining the bottleneck of infection forP. mirabilisduring UTI. (A–C) CBA/J mice were transurethrally inoculated with 107CFU. The inoculum contained

Updated on: January 25,2024 17

This gross mixture has big benefits for the study of bacteria

byUniversity of MichiganDetermining the bottleneck of infection forP. mirabilisduring UTI. (A–C) CBA/J mice were transurethrally inoculated with 107CFU. The inoculum contained

Updated on:January 25,2024 17

Review highlights the challenges and recent advances in targeted therapies for lupus nephritis

by Cactus CommunicationsSLE involves abnormal activation of both innate and adaptive immune responses, leading to systemic immune dysregulation and renal impairment. The complement system's dysfun

Updated on: January 26,2024 13

Review highlights the challenges and recent advances in targeted therapies for lupus nephritis

by Cactus CommunicationsSLE involves abnormal activation of both innate and adaptive immune responses, leading to systemic immune dysregulation and renal impairment. The complement system's dysfun

Updated on:January 26,2024 13

Scientists solve 18-year-old mystery and find the once-elusive source of a critical T cell population

by Delthia Ricks , Medical XpressPresence of Tcf7+CD8+T cells during the primary response to infection. (A) Experimental schematic: Naïve P14 cells (CD45.2) were transferred into congenica

Updated on: January 26,2024 17

Scientists solve 18-year-old mystery and find the once-elusive source of a critical T cell population

by Delthia Ricks , Medical XpressPresence of Tcf7+CD8+T cells during the primary response to infection. (A) Experimental schematic: Naïve P14 cells (CD45.2) were transferred into congenica

Updated on:January 26,2024 17

CAR T cell therapy could reach beyond cancer

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainEngineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can

Updated on: April 09,2024 18

CAR T cell therapy could reach beyond cancer

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainEngineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can

Updated on:April 09,2024 18

Study finds combination therapy does little to slow spine damage in radiographic axial spondyloarthritis patients

by American College of RheumatologyCumulative probability plot of mSASSS progression over 108 weeks of treatment. Credit: COmparison of the Effect of Treatment with NSAIDs Added to Anti-TNF Thera

Updated on: May 13,2024 8

Study finds combination therapy does little to slow spine damage in radiographic axial spondyloarthritis patients

by American College of RheumatologyCumulative probability plot of mSASSS progression over 108 weeks of treatment. Credit: COmparison of the Effect of Treatment with NSAIDs Added to Anti-TNF Thera

Updated on:May 13,2024 8

New genetic findings offer therapeutic approaches for incurable autoimmune disease SLE

by Stephan Wiegand,Dresden University of TechnologySingle-cell RNA sequencing of PBMCs of patient 3 and controls. (A) Uniform manifold approximation and projection (UMAP) of integrated data from

Updated on: April 26,2024 0

New genetic findings offer therapeutic approaches for incurable autoimmune disease SLE

by Stephan Wiegand,Dresden University of TechnologySingle-cell RNA sequencing of PBMCs of patient 3 and controls. (A) Uniform manifold approximation and projection (UMAP) of integrated data from

Updated on:April 26,2024 0

New genetic risk factors for rheumatoid arthritis revealed by analysis of multiple ancestry groups

by RIKENEnrichment of high PIP variants within open chromatin regions of 18 blood cell populations was analyzed by gchromVAR software. The horizontal dashed line indicates Bonferroni corrected P

Updated on: May 26,2024 6

New genetic risk factors for rheumatoid arthritis revealed by analysis of multiple ancestry groups

by RIKENEnrichment of high PIP variants within open chromatin regions of 18 blood cell populations was analyzed by gchromVAR software. The horizontal dashed line indicates Bonferroni corrected P

Updated on:May 26,2024 6