Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on: May 08,2024

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on:May 08,2024

Researchers discover immune system changes that support peanut allergy remission in children

by Murdoch Children's Research InstituteResearchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more target

Updated on: May 05,2024

Researchers discover immune system changes that support peanut allergy remission in children

by Murdoch Children's Research InstituteResearchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more target

Updated on:May 05,2024

Possible new biomarker for better detection of numerous inflammatory diseases

by Kiel UniversityTryptophan concentrations in the blood were significantly reduced in 9 of 13 chronic inflammatory diseases examined. Credit: S. Klahn, Exzellenzcluster PMITryptophan is an essen

Updated on: March 30,2024

Possible new biomarker for better detection of numerous inflammatory diseases

by Kiel UniversityTryptophan concentrations in the blood were significantly reduced in 9 of 13 chronic inflammatory diseases examined. Credit: S. Klahn, Exzellenzcluster PMITryptophan is an essen

Updated on:March 30,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on: March 27,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on:March 27,2024

Rituximab retreatment at clinical relapse cost-effective in RA

(HealthDay)—Rituximab retreatment at clinical relapse is at least as cost-effective as a more intensive regimen in longstanding rheumatoid arthritis (RA), according to a study published in the July is

Updated on: April 08,2024

Rituximab retreatment at clinical relapse cost-effective in RA

(HealthDay)—Rituximab retreatment at clinical relapse is at least as cost-effective as a more intensive regimen in longstanding rheumatoid arthritis (RA), according to a study published in the July is

Updated on:April 08,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024

Some severe COVID-19 cases linked to genetic mutations or antibodies that attack the body

by Howard Hughes Medical InstituteInfection with the novel coronavirus (gold spheres) can cause a range of symptoms. Some people with severe cases of COVID-19 have genetic mutations in key immuni

Updated on: May 08,2024

Some severe COVID-19 cases linked to genetic mutations or antibodies that attack the body

by Howard Hughes Medical InstituteInfection with the novel coronavirus (gold spheres) can cause a range of symptoms. Some people with severe cases of COVID-19 have genetic mutations in key immuni

Updated on:May 08,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on: June 15,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on:June 15,2024

Study finds racial gaps in renal complications persist for children with lupus

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that while hospit

Updated on: May 29,2024

Study finds racial gaps in renal complications persist for children with lupus

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that while hospit

Updated on:May 29,2024

A gene that plays a critical role in natural killer cell differentiation

by Bob Yirka , Medical XpressAn illustration of natural killer cells. Credit: Val Altounian / AAASA large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a

Updated on: March 25,2024

A gene that plays a critical role in natural killer cell differentiation

by Bob Yirka , Medical XpressAn illustration of natural killer cells. Credit: Val Altounian / AAASA large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a

Updated on:March 25,2024

Novel mechanism of ILC2 immune cell development may be involved in exacerbating allergic diseases

byChiba UniversityResearchers identify a G3SE-dependent mechanism of ILC2 development. Credit: Yosuke Toda and Arifumi Iwata from Chiba UniversityOverproduction of Group 2 innate lymphoid cells

Updated on: July 11,2024

Novel mechanism of ILC2 immune cell development may be involved in exacerbating allergic diseases

byChiba UniversityResearchers identify a G3SE-dependent mechanism of ILC2 development. Credit: Yosuke Toda and Arifumi Iwata from Chiba UniversityOverproduction of Group 2 innate lymphoid cells

Updated on:July 11,2024

Certain steps help lead to healthy pregnancies in women with rheumatoid arthritis

by WileyCredit: CC0 Public DomainFor women with rheumatoid arthritis (RA), taking certain steps to ensure that they have a healthy pregnancy leads to a reduced risk of complicated birth or miscar

Updated on: April 17,2024

Certain steps help lead to healthy pregnancies in women with rheumatoid arthritis

by WileyCredit: CC0 Public DomainFor women with rheumatoid arthritis (RA), taking certain steps to ensure that they have a healthy pregnancy leads to a reduced risk of complicated birth or miscar

Updated on:April 17,2024