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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
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Study: Rheumatoid arthritis plus depression may be deadly

Study: Rheumatoid arthritis plus depression may be deadly

Risk of mood-related mortality greater for men.(HealthDay)—People with rheumatoid arthritis have higher-than-normal rates of depression, which could increase their risk of death, according to a new st

Study: Rheumatoid arthritis plus depression may be deadly

Risk of mood-related mortality greater for men.(HealthDay)—People with rheumatoid arthritis have higher-than-normal rates of depression, which could increase their risk of death, according to a new st
ACR releases five 'Don'ts' for rheumatologists

ACR releases five 'Don'ts' for rheumatologists

As part of theChoosing Wiselycampaign, the American College of Rheumatology has issued a list of the top five tests and treatments commonly misordered by rheumatologists; the list has been

ACR releases five 'Don'ts' for rheumatologists

As part of theChoosing Wiselycampaign, the American College of Rheumatology has issued a list of the top five tests and treatments commonly misordered by rheumatologists; the list has been
Differences in T cells' functional state determine resistance to cancer therapy

Differences in T cells' functional state determine resistance to cancer therapy

by Massachusetts Institute of TechnologyThe researchers took this image of a tumor using immunofluorescence, a technique that allows them to stain tissue sections with fluorescently-labeled antib

Differences in T cells' functional state determine resistance to cancer therapy

by Massachusetts Institute of TechnologyThe researchers took this image of a tumor using immunofluorescence, a technique that allows them to stain tissue sections with fluorescently-labeled antib
A messenger substance considered to be inflammatory can alleviate asthma symptoms

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL
The secret lives of T cell receptors and their role in the immune response

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte
T-cells shown to infiltrate brain, cause respiratory distress in condition affecting the immunocompromised

T-cells shown to infiltrate brain, cause respiratory distress in condition affecting the immunocompromised

by Liz Ahlberg Touchstone |,University of Illinois at Urbana-ChampaignPulmonary dysfunction and mortality under the C-IRIS condition.ASchematic representation of the experiments and

T-cells shown to infiltrate brain, cause respiratory distress in condition affecting the immunocompromised

by Liz Ahlberg Touchstone |,University of Illinois at Urbana-ChampaignPulmonary dysfunction and mortality under the C-IRIS condition.ASchematic representation of the experiments and
Greater support needed to improve the treatment of knee osteoarthritis

Greater support needed to improve the treatment of knee osteoarthritis

by Curtin UniversityCredit: CC0 Public DomainA new Curtin University-led paper has outlined that many people living with knee osteoarthritis may be needlessly suffering or receiving the wrong tre

Greater support needed to improve the treatment of knee osteoarthritis

by Curtin UniversityCredit: CC0 Public DomainA new Curtin University-led paper has outlined that many people living with knee osteoarthritis may be needlessly suffering or receiving the wrong tre
Using molecular scissors to improve CAR-T cell therapy

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D
Long-term rituximab safe for patients with wegener's

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3
Research unveils metabolic strategies to enhance CAR-T cell therapy

Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di
First-in-human trial with CAR macrophages shows promise targeting solid tumors

First-in-human trial with CAR macrophages shows promise targeting solid tumors

by Caren Begun,University of PennsylvaniaCredit: Pixabay/CC0 Public DomainPreliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability a

First-in-human trial with CAR macrophages shows promise targeting solid tumors

by Caren Begun,University of PennsylvaniaCredit: Pixabay/CC0 Public DomainPreliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability a
Investigating healthy lifestyle and mortality in osteoarthritis

Investigating healthy lifestyle and mortality in osteoarthritis

by European Alliance of Associations for Rheumatology (EULAR)Credit: CC0 Public DomainHealthy lifestyles are thought to reduce mortality in the general population, but it is not known whether the same

Investigating healthy lifestyle and mortality in osteoarthritis

by European Alliance of Associations for Rheumatology (EULAR)Credit: CC0 Public DomainHealthy lifestyles are thought to reduce mortality in the general population, but it is not known whether the same