How a virus that infects 50% of people is helping develop new cancer treatments

by Rebecca Aicheler,The ConversationCredit: AI-generated imageMost of us have heard of viruses such asmeaslesandmumps—not to mention the more seriousHIVandEbo

Updated on: May 07,2024

How a virus that infects 50% of people is helping develop new cancer treatments

by Rebecca Aicheler,The ConversationCredit: AI-generated imageMost of us have heard of viruses such asmeaslesandmumps—not to mention the more seriousHIVandEbo

Updated on:May 07,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on: May 07,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on:May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

New study reveals how epithelial cells in the body naturally eliminate 'precancerous' ones

by Waseda UniversityWaseda University researchers identify the underlying mechanism behind the extrusion of precancerous cells by epithelial cells, a mechanism that prevents the formation of canc

Updated on: May 07,2024

New study reveals how epithelial cells in the body naturally eliminate 'precancerous' ones

by Waseda UniversityWaseda University researchers identify the underlying mechanism behind the extrusion of precancerous cells by epithelial cells, a mechanism that prevents the formation of canc

Updated on:May 07,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on: May 07,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on:May 07,2024

Dietary fiber in the gut may help with skin allergies, says new study

by Monash UniversityCredit: Unsplash/CC0 Public DomainA Monash University study exploring the emerging gut-skin axis has found that microbial fermentation of dietary fiber in the gut can protect

Updated on: May 07,2024

Dietary fiber in the gut may help with skin allergies, says new study

by Monash UniversityCredit: Unsplash/CC0 Public DomainA Monash University study exploring the emerging gut-skin axis has found that microbial fermentation of dietary fiber in the gut can protect

Updated on:May 07,2024

A small T cell switch with a big impact

by Julius-Maximilians-Universität WürzburgCredit: CC0 Public DomainT cells play a key role in the human immune system. They are capable of distinguishing diseased or foreign tissue from the body&

Updated on: May 07,2024

A small T cell switch with a big impact

by Julius-Maximilians-Universität WürzburgCredit: CC0 Public DomainT cells play a key role in the human immune system. They are capable of distinguishing diseased or foreign tissue from the body&

Updated on:May 07,2024

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on: May 06,2024

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on:May 06,2024

The 'greying' of T cells: Scientists pinpoint metabolic pathway behind age-related immunity loss

by Harvard Medical SchoolCredit: CC0 Public DomainThe elderly suffer more serious complications from infections and benefit less from vaccination than the general population. Scientists have long

Updated on: May 06,2024

The 'greying' of T cells: Scientists pinpoint metabolic pathway behind age-related immunity loss

by Harvard Medical SchoolCredit: CC0 Public DomainThe elderly suffer more serious complications from infections and benefit less from vaccination than the general population. Scientists have long

Updated on:May 06,2024

VAV1 gene mutations trigger T-cell tumors in mice

by University of TsukubaCredit: CC0 Public DomainLife is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and

Updated on: May 06,2024

VAV1 gene mutations trigger T-cell tumors in mice

by University of TsukubaCredit: CC0 Public DomainLife is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and

Updated on:May 06,2024

Cell adaptation in critically ill could be difference between life and death, new study shows

by Amy King,University of PlymouthGraphical abstract. Credit:Redox Biology(2021). DOI: 10.1016/j.redox.2021.101907Creating the best conditions for cells to make energy and survive cr

Updated on: May 06,2024

Cell adaptation in critically ill could be difference between life and death, new study shows

by Amy King,University of PlymouthGraphical abstract. Credit:Redox Biology(2021). DOI: 10.1016/j.redox.2021.101907Creating the best conditions for cells to make energy and survive cr

Updated on:May 06,2024

High body temperature increases resistance to pathogenic viral infections, new study finds

by University of Tokyo"Influenza Virus" by NIAID. Credit: Minami Nagai, Miyu Moriyama, Chiharu Ishii, Hirotake Mori, Hikaru Watanabe, Taku Nakahara, Takuji Yamada, Dai Ishikawa, Takamas

Updated on: May 06,2024

High body temperature increases resistance to pathogenic viral infections, new study finds

by University of Tokyo"Influenza Virus" by NIAID. Credit: Minami Nagai, Miyu Moriyama, Chiharu Ishii, Hirotake Mori, Hikaru Watanabe, Taku Nakahara, Takuji Yamada, Dai Ishikawa, Takamas

Updated on:May 06,2024