A cellular model system for drug development in fatty liver disease

by Eva Maria Wellnitz, Universitätsmedizin MannheimThe model system: Healthy liver cells of different origin are cultured in a 3D collagen sandwich system and development towards fatty liver cells is

Updated on: October 04,2024

A cellular model system for drug development in fatty liver disease

by Eva Maria Wellnitz, Universitätsmedizin MannheimThe model system: Healthy liver cells of different origin are cultured in a 3D collagen sandwich system and development towards fatty liver cells is

Updated on:October 04,2024

Nature:Pluripotent stem cells build liver-like organs to help treat liver disease

Updated on: April 22,2025

Nature:Pluripotent stem cells build liver-like organs to help treat liver disease

Updated on:April 22,2025

Markers of inflammation can predict 180-day mortality in cirrhosis

by Elana GotkineFor patients with newly diagnosed cirrhosis, markers of inflammation can predict 180-day mortality, but not liver-related admissions, according to a study published online Nov. 16 in&n

Updated on: January 29,2024

Markers of inflammation can predict 180-day mortality in cirrhosis

by Elana GotkineFor patients with newly diagnosed cirrhosis, markers of inflammation can predict 180-day mortality, but not liver-related admissions, according to a study published online Nov. 16 in&n

Updated on:January 29,2024

New insights into genetic mechanisms could improve treatment of liver fibrosis

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.109301The liver is not only the larges

Updated on: March 20,2024

New insights into genetic mechanisms could improve treatment of liver fibrosis

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.109301The liver is not only the larges

Updated on:March 20,2024

Maddening itch of liver disease comes from a surprising source

by Duke University School of NursingExcess lipids produced by liver failure signal an itching sensation directly to the skin cells, through a receptor called TRPV4 and a microRNA. Credit: Wolfgan

Updated on: May 29,2024

Maddening itch of liver disease comes from a surprising source

by Duke University School of NursingExcess lipids produced by liver failure signal an itching sensation directly to the skin cells, through a receptor called TRPV4 and a microRNA. Credit: Wolfgan

Updated on:May 29,2024

Cytoglobin: Key player in preventing liver disease

by Osaka City University6His tagged recombinant human CYGB (His-CYGB) was endocytosed into the HSCs via Clathrin-mediated pathway, scavenged ROS, such as O2- and OH-, and induced IFN-β secretion media

Updated on: May 09,2024

Cytoglobin: Key player in preventing liver disease

by Osaka City University6His tagged recombinant human CYGB (His-CYGB) was endocytosed into the HSCs via Clathrin-mediated pathway, scavenged ROS, such as O2- and OH-, and induced IFN-β secretion media

Updated on:May 09,2024

Providing clinicians with an AI sidekick to help to identify cirrhosis

by Sarah Dooley,Medical University of South CarolinaFuturistic illustration of a liver, suggesting use of artificial intelligence to improve liver health. Credit: Jihad Obeid, Medical University

Updated on: May 17,2024

Providing clinicians with an AI sidekick to help to identify cirrhosis

by Sarah Dooley,Medical University of South CarolinaFuturistic illustration of a liver, suggesting use of artificial intelligence to improve liver health. Credit: Jihad Obeid, Medical University

Updated on:May 17,2024

Inflammation discovery advances the fight against chronic liver disease

by QIMR Berghofer Medical Research InstituteInhibition of late endosome/lysosome function on ICAM-1 distribution in FTH-treated rat HSCs. Credit:Science Signaling(2024). DOI: 10.1126/scisi

Updated on: April 27,2024

Inflammation discovery advances the fight against chronic liver disease

by QIMR Berghofer Medical Research InstituteInhibition of late endosome/lysosome function on ICAM-1 distribution in FTH-treated rat HSCs. Credit:Science Signaling(2024). DOI: 10.1126/scisi

Updated on:April 27,2024

YKT6 gene variants cause a new neurological disorder, finds study

byTexas Children's HospitalCredit: Unsplash/CC0 Public DomainA recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characteri

Updated on: April 06,2024

YKT6 gene variants cause a new neurological disorder, finds study

byTexas Children's HospitalCredit: Unsplash/CC0 Public DomainA recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characteri

Updated on:April 06,2024

Researchers identify a potential therapeutic target against cirrhosis and liver inflammation

by University of BarcelonaA new study by a team of the University of Barcelona could promote the design of drugs to treat these pathologies. Credit: University of BarcelonaThe RNF41 protein could

Updated on: January 29,2024

Researchers identify a potential therapeutic target against cirrhosis and liver inflammation

by University of BarcelonaA new study by a team of the University of Barcelona could promote the design of drugs to treat these pathologies. Credit: University of BarcelonaThe RNF41 protein could

Updated on:January 29,2024

New algorithm can predict advanced liver disease

(HealthDay)—A model that uses routine primary care data can predict the risk for advanced liver disease, according to a study published online Feb. 11 inBMJ Open.Theresa Hydes, Ph.D., from the U

Updated on: April 29,2024

New algorithm can predict advanced liver disease

(HealthDay)—A model that uses routine primary care data can predict the risk for advanced liver disease, according to a study published online Feb. 11 inBMJ Open.Theresa Hydes, Ph.D., from the U

Updated on:April 29,2024

New standards to quantify hepatitis B virus reservoirs in liver cells

by Nicola Wittekindt, Deutsches Zentrum für InfektionsforschungThe effect of different DNA extraction methods on cccDNA quantification by qPCR and SB in HBV-infected USG mouse liver tissue. (A) Schema

Updated on: May 29,2024

New standards to quantify hepatitis B virus reservoirs in liver cells

by Nicola Wittekindt, Deutsches Zentrum für InfektionsforschungThe effect of different DNA extraction methods on cccDNA quantification by qPCR and SB in HBV-infected USG mouse liver tissue. (A) Schema

Updated on:May 29,2024