Researchers stimulate gene that enhances CAR T-cell treatments for solid tumors

byPeter MacCallum Cancer CentreFOX1-ADA overexpression enhances CAR T cell polyfunctionality. a, Schematic of tumor cell coculture assay. b, IFNγ and TNF production following each round of E0771

Updated on: April 28,2024

Researchers stimulate gene that enhances CAR T-cell treatments for solid tumors

byPeter MacCallum Cancer CentreFOX1-ADA overexpression enhances CAR T cell polyfunctionality. a, Schematic of tumor cell coculture assay. b, IFNγ and TNF production following each round of E0771

Updated on:April 28,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

Earlier onset of disease and aging in the most deprived could be linked to gut health, poor diet

by University of GlasgowCredit: Unsplash/CC0 Public DomainAn earlier onset of disease and aging in the most deprived could be linked to gut health and poor diet.A new, first-of-its-kind-study, le

Updated on: March 13,2024

Earlier onset of disease and aging in the most deprived could be linked to gut health, poor diet

by University of GlasgowCredit: Unsplash/CC0 Public DomainAn earlier onset of disease and aging in the most deprived could be linked to gut health and poor diet.A new, first-of-its-kind-study, le

Updated on:March 13,2024

5 facts about celiac disease

by Rush University Medical CenterCredit: Pixabay/CC0 Public DomainFor people with celiac disease, foods as seemingly wholesome as whole grain bread can be dangerous.Why? Having celiac means that

Updated on: June 17,2024

5 facts about celiac disease

by Rush University Medical CenterCredit: Pixabay/CC0 Public DomainFor people with celiac disease, foods as seemingly wholesome as whole grain bread can be dangerous.Why? Having celiac means that

Updated on:June 17,2024

Smart pill could be game changer in diagnosis, treatment of bowel diseases

by Elizabeth A. Thomson,Materials Research Laboratory, Massachusetts Institute of TechnologyMIT and Boston University researchers and colleagues report a smart pill the size of a blueberry that

Updated on: March 12,2024

Smart pill could be game changer in diagnosis, treatment of bowel diseases

by Elizabeth A. Thomson,Materials Research Laboratory, Massachusetts Institute of TechnologyMIT and Boston University researchers and colleagues report a smart pill the size of a blueberry that

Updated on:March 12,2024

Stomach cancer atlas maps path to better treatments

by Federico Graciano,Duke-NUS Medical SchoolFigure 1. UMAPs depicting cell lineages marked by genes specific to each cluster. The epithelial cell meta-cluster is marked by CDH1 expression and th

Updated on: May 11,2024

Stomach cancer atlas maps path to better treatments

by Federico Graciano,Duke-NUS Medical SchoolFigure 1. UMAPs depicting cell lineages marked by genes specific to each cluster. The epithelial cell meta-cluster is marked by CDH1 expression and th

Updated on:May 11,2024

London researchers first in world to use new device for feeding tube insertion

by Lawson Health Research InstituteCredit: CC0 Public DomainA team of clinician researchers from Lawson Health Research Institute have partnered with medical device company CoapTech LLC to study

Updated on: May 29,2024

London researchers first in world to use new device for feeding tube insertion

by Lawson Health Research InstituteCredit: CC0 Public DomainA team of clinician researchers from Lawson Health Research Institute have partnered with medical device company CoapTech LLC to study

Updated on:May 29,2024

Constipation associated with increased risk of hypertension, cardiovascular events in elderly Australian patients

by La Trobe UniversitySummary of the findings. This study found that constipation was positively associated with hypertension and cardiovascular events. CI, confidence interval; OR, odds ratio. T

Updated on: March 26,2024

Constipation associated with increased risk of hypertension, cardiovascular events in elderly Australian patients

by La Trobe UniversitySummary of the findings. This study found that constipation was positively associated with hypertension and cardiovascular events. CI, confidence interval; OR, odds ratio. T

Updated on:March 26,2024

Gut microbiota-derived 7-DHC found to ameliorate circadian rhythm disorders and inflammatory bowel disease

Gut microbiota-derived 7-DHC found to ameliorate circadian rhythm disorders and inflammatory bowel diseaseby Higher Education Press7-DHC alleviated experimental colitis with circadian disruption. Cred

Updated on: January 24,2024

Gut microbiota-derived 7-DHC found to ameliorate circadian rhythm disorders and inflammatory bowel disease

Gut microbiota-derived 7-DHC found to ameliorate circadian rhythm disorders and inflammatory bowel diseaseby Higher Education Press7-DHC alleviated experimental colitis with circadian disruption. Cred

Updated on:January 24,2024

Engineered organism could diagnose Crohn's disease flareups

by Rice UniversityRice University researchers engineered a strain of the gut bacteria E. coli to detect gastrointestinal acidosis. The organism produces fluorescent molecules that allow researche

Updated on: June 17,2024

Engineered organism could diagnose Crohn's disease flareups

by Rice UniversityRice University researchers engineered a strain of the gut bacteria E. coli to detect gastrointestinal acidosis. The organism produces fluorescent molecules that allow researche

Updated on:June 17,2024

Researchers find increased intestinal permeability is precursor of celiac disease in pediatric study

by Susie Flaherty,Massachusetts General HospitalCredit: CC0 Public DomainResearchers from Mass General for Children and Italy have identified a potential biomarker preceding the development of c

Updated on: January 24,2024

Researchers find increased intestinal permeability is precursor of celiac disease in pediatric study

by Susie Flaherty,Massachusetts General HospitalCredit: CC0 Public DomainResearchers from Mass General for Children and Italy have identified a potential biomarker preceding the development of c

Updated on:January 24,2024

Online atlas shows strong link between gut bacteria and metabolites

by Uppsala UniversityThe study is based on analyses of both fecal and blood samples from 8,583 participants in the Swedish CArdioPulmonary bioImage Study (SCAPIS). Credit: Petra OlssonThere are s

Updated on: March 25,2024

Online atlas shows strong link between gut bacteria and metabolites

by Uppsala UniversityThe study is based on analyses of both fecal and blood samples from 8,583 participants in the Swedish CArdioPulmonary bioImage Study (SCAPIS). Credit: Petra OlssonThere are s

Updated on:March 25,2024