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Mutation mapping shows errors in protein location are a common cause of disease

Mutation mapping shows errors in protein location are a common cause of disease

by Anika Hazra,University of TorontoCredit:Cell(2024). DOI: 10.1016/j.cell.2024.09.003An international team led by researchers at the University of Toronto and the Broad Institute of

Mutation mapping shows errors in protein location are a common cause of disease

by Anika Hazra,University of TorontoCredit:Cell(2024). DOI: 10.1016/j.cell.2024.09.003An international team led by researchers at the University of Toronto and the Broad Institute of
Genetics may influence the body's response to low oxygen, study finds

Genetics may influence the body's response to low oxygen, study finds

byUniversity of PittsburghImmunofluorescent staining for the lncRNA fragment in a diseased pulmonary vessel from a patient with pulmonary arterial hypertension. Credit: Thomas BerteroUniversity

Genetics may influence the body's response to low oxygen, study finds

byUniversity of PittsburghImmunofluorescent staining for the lncRNA fragment in a diseased pulmonary vessel from a patient with pulmonary arterial hypertension. Credit: Thomas BerteroUniversity
Diabetes drug shows promise against Parkinson's in clinical study

Diabetes drug shows promise against Parkinson's in clinical study

by By Issam Ahmed and Lucie AubourgPeople play table tennis at the Ping Pong Parkinson initiative in Berlin on April 11, 2023, World Parkinson's Day -- the devastating disorder affects 10 million

Diabetes drug shows promise against Parkinson's in clinical study

by By Issam Ahmed and Lucie AubourgPeople play table tennis at the Ping Pong Parkinson initiative in Berlin on April 11, 2023, World Parkinson's Day -- the devastating disorder affects 10 million
Chronic Hepatitis B

Chronic Hepatitis B

RESEARCH29 January 2024New hepatitis B study reveals how viruses adapt to low-oxygen environments, such as those found deep within the liver, opening up possible new therapeutic targets for liver path

Chronic Hepatitis B

RESEARCH29 January 2024New hepatitis B study reveals how viruses adapt to low-oxygen environments, such as those found deep within the liver, opening up possible new therapeutic targets for liver path
COPD and the effect of low-dose cadmium, a highly toxic metal, on airway epithelial cells

COPD and the effect of low-dose cadmium, a highly toxic metal, on airway epithelial cells

FEBRUARY 2, 2024 Editors' notesby Jeff Hansen,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainCigarette smoke exposure is associated with the development and severity of

COPD and the effect of low-dose cadmium, a highly toxic metal, on airway epithelial cells

FEBRUARY 2, 2024 Editors' notesby Jeff Hansen,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainCigarette smoke exposure is associated with the development and severity of
Adding diversity to your research process: A new system

Adding diversity to your research process: A new system

by Hoag Levins,University of PennsylvaniaCredit: University of PennsylvaniaInsufficient diversity in clinical trials and other research cohorts is widely recognized as one of American health car

Adding diversity to your research process: A new system

by Hoag Levins,University of PennsylvaniaCredit: University of PennsylvaniaInsufficient diversity in clinical trials and other research cohorts is widely recognized as one of American health car
Researchers halt progression of Parkinson's disease in mouse model

Researchers halt progression of Parkinson's disease in mouse model

NOVEMBER 14, 2023by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterGeneration and characterization of Usp30 KO mice. a Schematic of gene targeting to generate the Usp30 KO mice. b Bar g

Researchers halt progression of Parkinson's disease in mouse model

NOVEMBER 14, 2023by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterGeneration and characterization of Usp30 KO mice. a Schematic of gene targeting to generate the Usp30 KO mice. b Bar g
Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

by Claes Björnberg,Umea UniversityAxon and NMJ integrity is partially rescued by overexpression of fhl2b in trunk muscle of 5 dpf dmd-/-zebrafish larvae. Credit: https://umu.diva-portal.or

Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

by Claes Björnberg,Umea UniversityAxon and NMJ integrity is partially rescued by overexpression of fhl2b in trunk muscle of 5 dpf dmd-/-zebrafish larvae. Credit: https://umu.diva-portal.or
Reframing cerebral palsy as a lifelong physical disability could improve adult care, researchers say

Reframing cerebral palsy as a lifelong physical disability could improve adult care, researchers say

by Valerie Goodwin,University of MichiganA boy is supported by his family and care team as a child but feels left with questions as an adult. Credit: Justine Ross, Michigan MedicineIn the United

Reframing cerebral palsy as a lifelong physical disability could improve adult care, researchers say

by Valerie Goodwin,University of MichiganA boy is supported by his family and care team as a child but feels left with questions as an adult. Credit: Justine Ross, Michigan MedicineIn the United
Enhancing hypoxia-activated prodrug anticancer therapy

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres
New study shows a role for cholesterol in pain perception

New study shows a role for cholesterol in pain perception

FEBRUARY 27, 2024byUniversity of FloridaA cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cell

New study shows a role for cholesterol in pain perception

FEBRUARY 27, 2024byUniversity of FloridaA cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cell
Experimental compound extends life in amyotrophic lateral sclerosis mouse model

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i