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Breakthroughs
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Medical imaging breakthroughs aim to bring the invisible to light

Medical imaging breakthroughs aim to bring the invisible to light

by Valérie Geneux,Ecole Polytechnique Federale de LausanneSpinal cord fMRI. Credit: EPFL—CC-BY-SA 4.0Medical imaging technology—such as MRI, ultrasound and X-ray—is gaining in power and precisio

Medical imaging breakthroughs aim to bring the invisible to light

by Valérie Geneux,Ecole Polytechnique Federale de LausanneSpinal cord fMRI. Credit: EPFL—CC-BY-SA 4.0Medical imaging technology—such as MRI, ultrasound and X-ray—is gaining in power and precisio
Researcher identifies key mechanism in Parkinson's disease

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec
Scientists discover a potential way to repair synapses damaged in Alzheimer's disease

Scientists discover a potential way to repair synapses damaged in Alzheimer's disease

FEBRUARY 1, 2024by Buck Institute for Research on AgingThe art depicts the recovery of the functional plasticity at synapses on neurons despite tau-induced toxicity in the brain. Credit: Larissa Brown

Scientists discover a potential way to repair synapses damaged in Alzheimer's disease

FEBRUARY 1, 2024by Buck Institute for Research on AgingThe art depicts the recovery of the functional plasticity at synapses on neurons despite tau-induced toxicity in the brain. Credit: Larissa Brown
Researchers uncover 'circular logic' of RNAs in Parkinson's disease

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used
Small RNAs take on the big task of helping skin wounds heal better and faster with minimal scarring

Small RNAs take on the big task of helping skin wounds heal better and faster with minimal scarring

 Editors' notesbyElsevierDeposition of laminin into wound bed contributes to blood vessel growth, which in turn, feeds normal skin regeneration. W—wound, BV—blood vessels. Credit:The A

Small RNAs take on the big task of helping skin wounds heal better and faster with minimal scarring

 Editors' notesbyElsevierDeposition of laminin into wound bed contributes to blood vessel growth, which in turn, feeds normal skin regeneration. W—wound, BV—blood vessels. Credit:The A
Quest for personalized medicine hits a snag: Current models have limited effectiveness to predict treatments, says study

Quest for personalized medicine hits a snag: Current models have limited effectiveness to predict treatments, says study

JANUARY 11, 2024by Bill Hathaway,Yale UniversityCredit: Unsplash/CC0 Public DomainThe quest for personalized medicine, a medical approach in which practitioners use a patient's unique geneti

Quest for personalized medicine hits a snag: Current models have limited effectiveness to predict treatments, says study

JANUARY 11, 2024by Bill Hathaway,Yale UniversityCredit: Unsplash/CC0 Public DomainThe quest for personalized medicine, a medical approach in which practitioners use a patient's unique geneti
Perfecting 3D-printed blood vessels with pores

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman
Protein production glitches in Huntington's disease revealed

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe
Blended antioxidant supplement found to improve cognition and memory in aged mice

Blended antioxidant supplement found to improve cognition and memory in aged mice

by Shibaura Institute of TechnologyAdministration of Twendee X (TwX) improves spatial learning ability in aged mice. The spatial cognition test's average goal time (escape latency) is shown i

Blended antioxidant supplement found to improve cognition and memory in aged mice

by Shibaura Institute of TechnologyAdministration of Twendee X (TwX) improves spatial learning ability in aged mice. The spatial cognition test's average goal time (escape latency) is shown i
Pancreas cells in people who have died show significant signs of stress

Pancreas cells in people who have died show significant signs of stress

by American Physiological SocietyCredit:Function(2024). DOI: 10.1093/function/zqae015People with type 1 diabetes require daily insulin shots to regulate their blood sugar levels. This

Pancreas cells in people who have died show significant signs of stress

by American Physiological SocietyCredit:Function(2024). DOI: 10.1093/function/zqae015People with type 1 diabetes require daily insulin shots to regulate their blood sugar levels. This
Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX
Research provides further evidence that epigenetic changes can cause type 2 diabetes

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc