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ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r
The dual role of well-known protein sheds light on Parkinson's disease mechanisms

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th
Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever
Mechanobiomaterials: A rising field using mechanobiology principles to program functional biomaterials

Mechanobiomaterials: A rising field using mechanobiology principles to program functional biomaterials

by Shanghai Jiao Tong University Journal CenterA closed-loop workflow of designing mechanobiomaterials. Credit: All authorsA group has proposed a new concept of mechanobiomaterials, which is inspired

Mechanobiomaterials: A rising field using mechanobiology principles to program functional biomaterials

by Shanghai Jiao Tong University Journal CenterA closed-loop workflow of designing mechanobiomaterials. Credit: All authorsA group has proposed a new concept of mechanobiomaterials, which is inspired
How transcription factors influence insulin-producing beta cells

How transcription factors influence insulin-producing beta cells

JANUARY 31, 2024by Melissa Rohman,Northwestern UniversityCredit:Cell Metabolism(2024). DOI: 10.1016/j.cmet.2023.11.018A recent study from the laboratory of Joseph Bass, MD, Ph.D., th

How transcription factors influence insulin-producing beta cells

JANUARY 31, 2024by Melissa Rohman,Northwestern UniversityCredit:Cell Metabolism(2024). DOI: 10.1016/j.cmet.2023.11.018A recent study from the laboratory of Joseph Bass, MD, Ph.D., th
New technique for revealing genetic repeats yields surprising insights into Huntington's disease

New technique for revealing genetic repeats yields surprising insights into Huntington's disease

byRockefeller UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechani

New technique for revealing genetic repeats yields surprising insights into Huntington's disease

byRockefeller UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechani
Researcher explores sex-specific features of HIV

Researcher explores sex-specific features of HIV

FEBRUARY 6, 2024by Linell Smith,Johns Hopkins UniversityEileen Scully. Credit: Johns Hopkins MedicineEarly in her career, Johns Hopkins physician-scientist Eileen Scully began to explore ways th

Researcher explores sex-specific features of HIV

FEBRUARY 6, 2024by Linell Smith,Johns Hopkins UniversityEileen Scully. Credit: Johns Hopkins MedicineEarly in her career, Johns Hopkins physician-scientist Eileen Scully began to explore ways th
Color-adjusting technique for histopathology image datasets could help empower machine-learning-based diagnostic tools

Color-adjusting technique for histopathology image datasets could help empower machine-learning-based diagnostic tools

bySPIETissue image datasets processed by stained SAN (bottom row) achieve color distributions that are more consistent than those processed using other techniques. Such consistency is essential

Color-adjusting technique for histopathology image datasets could help empower machine-learning-based diagnostic tools

bySPIETissue image datasets processed by stained SAN (bottom row) achieve color distributions that are more consistent than those processed using other techniques. Such consistency is essential
Follow-up colonoscopy rate low within six months of abnormal stool test

Follow-up colonoscopy rate low within six months of abnormal stool test

by Elana GotkineFewer than half of adults have a follow-up colonoscopy within six months following an abnormal stool-based screening test (SBT) for colorectal cancer (CRC), according to a study publis

Follow-up colonoscopy rate low within six months of abnormal stool test

by Elana GotkineFewer than half of adults have a follow-up colonoscopy within six months following an abnormal stool-based screening test (SBT) for colorectal cancer (CRC), according to a study publis
Researchers define new subtypes of common brain disorder

Researchers define new subtypes of common brain disorder

by Mark Reynolds,Washington University School of MedicineAn MRI scan shows a Chiari type-1 malformation, in which the cerebellum extends beyond the gap in the skull where it connects to the spin

Researchers define new subtypes of common brain disorder

by Mark Reynolds,Washington University School of MedicineAn MRI scan shows a Chiari type-1 malformation, in which the cerebellum extends beyond the gap in the skull where it connects to the spin
Researchers halt progression of Parkinson's disease in mouse model

Researchers halt progression of Parkinson's disease in mouse model

NOVEMBER 14, 2023by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterGeneration and characterization of Usp30 KO mice. a Schematic of gene targeting to generate the Usp30 KO mice. b Bar g

Researchers halt progression of Parkinson's disease in mouse model

NOVEMBER 14, 2023by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterGeneration and characterization of Usp30 KO mice. a Schematic of gene targeting to generate the Usp30 KO mice. b Bar g