Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on: March 13,2024 13

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on:March 13,2024 13

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc

Updated on: March 13,2024 5

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc

Updated on:March 13,2024 5

Researchers identify promising protein candidate for metabolic disease treatment

byUniversity of SaskatchewanHepG2/C3A cells express NUCB1/NLP and NUCB2/NESF-1. Credit:Communications Biology(2024). DOI: 10.1038/s42003-024-06314-2University of Saskatchewan (USask)

Updated on: May 30,2024 0

Researchers identify promising protein candidate for metabolic disease treatment

byUniversity of SaskatchewanHepG2/C3A cells express NUCB1/NLP and NUCB2/NESF-1. Credit:Communications Biology(2024). DOI: 10.1038/s42003-024-06314-2University of Saskatchewan (USask)

Updated on:May 30,2024 0

Researchers pinpoint issue that could be hampering common chemotherapy drug

by Anika Hazra,University of TorontoGenome-wide CRISPR–Cas9 screens reveal modulators of gemcitabine sensitivity. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00742-zResearche

Updated on: March 28,2024 0

Researchers pinpoint issue that could be hampering common chemotherapy drug

by Anika Hazra,University of TorontoGenome-wide CRISPR–Cas9 screens reveal modulators of gemcitabine sensitivity. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00742-zResearche

Updated on:March 28,2024 0

Working conditions can explain educational differences in heart disease mortality

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainResearchers from the Institute of Environmental Medicine at Karolinska Institutet have found that low influence and opportunities for deve

Updated on: April 28,2024 0

Working conditions can explain educational differences in heart disease mortality

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainResearchers from the Institute of Environmental Medicine at Karolinska Institutet have found that low influence and opportunities for deve

Updated on:April 28,2024 0

How an Addicted Brain Works

Updated on: August 26,2024 0

How an Addicted Brain Works

Updated on:August 26,2024 0

Organs-on-chips provide insights into molecular mechanisms of disease, facilitate design of newer treatment strategies

by Xia & He Publishing Inc.An illustration of organ-on-chip simulating the biological microenvironment. Credit:Journal of Exploratory Research in Pharmacology(2024). DOI: 10.14218/JERP

Updated on: July 23,2024 0

Organs-on-chips provide insights into molecular mechanisms of disease, facilitate design of newer treatment strategies

by Xia & He Publishing Inc.An illustration of organ-on-chip simulating the biological microenvironment. Credit:Journal of Exploratory Research in Pharmacology(2024). DOI: 10.14218/JERP

Updated on:July 23,2024 0

Why MDMA did NOT get FDA approval

Updated on: September 01,2024 0

Why MDMA did NOT get FDA approval

Updated on:September 01,2024 0

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Updated on: March 28,2024 0

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Updated on:March 28,2024 0

CBD products don't ease pain and are potentially harmful, study finds

by Vittoria D'Alessio,University of BathCredit: Unsplash/CC0 Public DomainThere is no evidence that CBD products reduce chronic pain, and taking them is a waste of money and potentially harm

Updated on: March 28,2024 0

CBD products don't ease pain and are potentially harmful, study finds

by Vittoria D'Alessio,University of BathCredit: Unsplash/CC0 Public DomainThere is no evidence that CBD products reduce chronic pain, and taking them is a waste of money and potentially harm

Updated on:March 28,2024 0

Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

by Steven Lee,University of Texas Health Science Center at San AntonioCredit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.02.033Magnesium is a mineral critical to a wide range of

Updated on: March 30,2024 0

Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

by Steven Lee,University of Texas Health Science Center at San AntonioCredit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.02.033Magnesium is a mineral critical to a wide range of

Updated on:March 30,2024 0

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)HEALTHMEDICAL SCIENCESMENTAL HEALTHRESEARCH29 January 2024Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Diso

Updated on: March 11,2024 15

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)HEALTHMEDICAL SCIENCESMENTAL HEALTHRESEARCH29 January 2024Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Diso

Updated on:March 11,2024 15