Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Profiling of LAR-RPTP microexon expression repertoires by targeted deep RNA sequencing Credit:Nature Communications(2024). DOI

Updated on: March 30,2024 0

Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Profiling of LAR-RPTP microexon expression repertoires by targeted deep RNA sequencing Credit:Nature Communications(2024). DOI

Updated on:March 30,2024 0

Researchers advance understanding of Parkinson's disease

byUniversity of GalwaySchematic representation of the experimental design and procedures followed in this study. The study was designed for the region-specific and temporal characterization of t

Updated on: April 28,2024 0

Researchers advance understanding of Parkinson's disease

byUniversity of GalwaySchematic representation of the experimental design and procedures followed in this study. The study was designed for the region-specific and temporal characterization of t

Updated on:April 28,2024 0

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used

Updated on: March 13,2024 6

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used

Updated on:March 13,2024 6

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N

Updated on: March 30,2024 10

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N

Updated on:March 30,2024 10

First clinical trial of vosoritide for children with hypochondroplasia shows increased growth

byChildren's National HospitalStanding height SDS. Credit:eClinicalMedicine(2024). DOI: 10.1016/j.eclinm.2024.102591Vosoritide's first global Phase II study showed an average

Updated on: April 28,2024 0

First clinical trial of vosoritide for children with hypochondroplasia shows increased growth

byChildren's National HospitalStanding height SDS. Credit:eClinicalMedicine(2024). DOI: 10.1016/j.eclinm.2024.102591Vosoritide's first global Phase II study showed an average

Updated on:April 28,2024 0

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman

Updated on: March 25,2024 5

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman

Updated on:March 25,2024 5

Researchers are using RNA in a new approach to fight HIV

FEBRUARY 20, 2024byUniversity of WaterlooGraphical abstract. Credit:Journal of Controlled Release(2024). DOI: 10.1016/j.jconrel.2023.12.043Society learned about the value of mRNA dur

Updated on: March 30,2024 8

Researchers are using RNA in a new approach to fight HIV

FEBRUARY 20, 2024byUniversity of WaterlooGraphical abstract. Credit:Journal of Controlled Release(2024). DOI: 10.1016/j.jconrel.2023.12.043Society learned about the value of mRNA dur

Updated on:March 30,2024 8

Exercise and Liraglutide: Effects on Weight Loss and Bone Health

This article delves into a study that investigates the effects of exercise, liraglutide, and their combination on weight loss and bone mineral density (BMD) in individuals with obesity.

Updated on: July 24,2024 0

Exercise and Liraglutide: Effects on Weight Loss and Bone Health

This article delves into a study that investigates the effects of exercise, liraglutide, and their combination on weight loss and bone mineral density (BMD) in individuals with obesity.

Updated on:July 24,2024 0

Pancreas cells in people who have died show significant signs of stress

by American Physiological SocietyCredit:Function(2024). DOI: 10.1093/function/zqae015People with type 1 diabetes require daily insulin shots to regulate their blood sugar levels. This

Updated on: April 06,2024 0

Pancreas cells in people who have died show significant signs of stress

by American Physiological SocietyCredit:Function(2024). DOI: 10.1093/function/zqae015People with type 1 diabetes require daily insulin shots to regulate their blood sugar levels. This

Updated on:April 06,2024 0

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on: March 28,2024 1

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on:March 28,2024 1

The phageome: A hidden kingdom within your gut

Updated on: August 15,2024 0

The phageome: A hidden kingdom within your gut

Updated on:August 15,2024 0

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on: March 13,2024 13

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on:March 13,2024 13