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Medical research
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Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic
Scientists develop 'safe' bone grafts from cow bones to heal bone fractures and injuries

Scientists develop 'safe' bone grafts from cow bones to heal bone fractures and injuries

byUniversity of SharjahRepresentative images of immunohistochemical staining of DMB and DCC implantation sites to visualize the intensity distribution of osteogenic factors. Credit:PLOS ON

Scientists develop 'safe' bone grafts from cow bones to heal bone fractures and injuries

byUniversity of SharjahRepresentative images of immunohistochemical staining of DMB and DCC implantation sites to visualize the intensity distribution of osteogenic factors. Credit:PLOS ON
Understanding what causes trastuzumab's cardiotoxicity

Understanding what causes trastuzumab's cardiotoxicity

byMary Ann Liebert, IncCredit: Pixabay/CC0 Public DomainA new meta-analysispublishedinOMICS: A Journal of Integrative Biologyhelps shed light on how changes in mitochondr

Understanding what causes trastuzumab's cardiotoxicity

byMary Ann Liebert, IncCredit: Pixabay/CC0 Public DomainA new meta-analysispublishedinOMICS: A Journal of Integrative Biologyhelps shed light on how changes in mitochondr
Evaluating selpercatinib for the treatment of non-small cell lung cancer

Evaluating selpercatinib for the treatment of non-small cell lung cancer

by D'Or Institute for Research and EducationCredit: Unsplash/CC0 Public DomainA phase III LIBRETTO-431 multicenter study has evaluated the efficacy and safety of selpercatinib compared to control

Evaluating selpercatinib for the treatment of non-small cell lung cancer

by D'Or Institute for Research and EducationCredit: Unsplash/CC0 Public DomainA phase III LIBRETTO-431 multicenter study has evaluated the efficacy and safety of selpercatinib compared to control
FDA approves oral Duvyzat for Duchenne muscular dystrophy

FDA approves oral Duvyzat for Duchenne muscular dystrophy

by Lori SolomonThe U.S. Food and Drug Administration has approved Duvyzat (givinostat) as an oral medication for the treatment of Duchenne muscular dystrophy (DMD) in patients six years of age and old

FDA approves oral Duvyzat for Duchenne muscular dystrophy

by Lori SolomonThe U.S. Food and Drug Administration has approved Duvyzat (givinostat) as an oral medication for the treatment of Duchenne muscular dystrophy (DMD) in patients six years of age and old
Five-day antibiotic course noninferior for pediatric febrile UTI

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c
A California panel is holding up studies on psychedelics: Some researchers want it gone

A California panel is holding up studies on psychedelics: Some researchers want it gone

JANUARY 19, 2024by Emily Alpert Reyes, Los Angeles TimesCredit: Pixabay/CC0 Public DomainAt the Pacific Neuroscience Institute in Santa Monica, scientists are eager to explore whether a psychedelic ch

A California panel is holding up studies on psychedelics: Some researchers want it gone

JANUARY 19, 2024by Emily Alpert Reyes, Los Angeles TimesCredit: Pixabay/CC0 Public DomainAt the Pacific Neuroscience Institute in Santa Monica, scientists are eager to explore whether a psychedelic ch
Researchers shed light on the molecular causes of different functions of opioid receptors

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti
How does HIV get into the cell's center to kickstart infection?

How does HIV get into the cell's center to kickstart infection?

JANUARY 24, 2024 Editors' notesbyUniversity of New South WalesIntact HIV-1 CLPs penetrate Nup98 condensates via FG-binding pocket. Credit:Nature(2024). DOI: 10.1038/s41586-023-06

How does HIV get into the cell's center to kickstart infection?

JANUARY 24, 2024 Editors' notesbyUniversity of New South WalesIntact HIV-1 CLPs penetrate Nup98 condensates via FG-binding pocket. Credit:Nature(2024). DOI: 10.1038/s41586-023-06
Combined antibiotics more effective against Lyme disease: Study

Combined antibiotics more effective against Lyme disease: Study

by Leslie Tate,Tulane UniversityThe study findings could pave the way for improved Lyme disease treatments, particularly in persistent cases, said lead researcher Monica Embers, PhD, associate p

Combined antibiotics more effective against Lyme disease: Study

by Leslie Tate,Tulane UniversityThe study findings could pave the way for improved Lyme disease treatments, particularly in persistent cases, said lead researcher Monica Embers, PhD, associate p
The year in opioid settlements: 5 things you need to know

The year in opioid settlements: 5 things you need to know

DECEMBER 30, 2023 Editors' notesby Aneri Pattani, KFF Health NewsCredit: Pixabay/CC0 Public DomainThis year, about $1.5 billion has landed in state and local government coffers from court settleme

The year in opioid settlements: 5 things you need to know

DECEMBER 30, 2023 Editors' notesby Aneri Pattani, KFF Health NewsCredit: Pixabay/CC0 Public DomainThis year, about $1.5 billion has landed in state and local government coffers from court settleme