Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

byThe Mount Sinai HospitalLoGoFunc identifies harmful (left) and harmless (right) genetic variations in the Vasopressin V2 receptor protein using a structure predicted by AlphaFold2. This helps

Updated on: January 02,2024 16

Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

byThe Mount Sinai HospitalLoGoFunc identifies harmful (left) and harmless (right) genetic variations in the Vasopressin V2 receptor protein using a structure predicted by AlphaFold2. This helps

Updated on:January 02,2024 16

Anxiety drug pregabalin is linked to a rising number of deaths. Here's what you should know

by Ian Hamilton and Harry Sumnall,The ConversationCredit: Pixabay/CC0 Public DomainThere has been a significant rise in deaths linked to the commonly prescribed anxiety drug, pregabalin. While i

Updated on: March 20,2024 13

Anxiety drug pregabalin is linked to a rising number of deaths. Here's what you should know

by Ian Hamilton and Harry Sumnall,The ConversationCredit: Pixabay/CC0 Public DomainThere has been a significant rise in deaths linked to the commonly prescribed anxiety drug, pregabalin. While i

Updated on:March 20,2024 13

Industrial societies losing healthy gut microbes, finds study

by Ben-Gurion University of the NegevCellulose degrading gut bacteria of hominids across evolutionary time. Previously unknown human gut cellulolytic ruminococcal species are highly prevalent in

Updated on: March 28,2024 0

Industrial societies losing healthy gut microbes, finds study

by Ben-Gurion University of the NegevCellulose degrading gut bacteria of hominids across evolutionary time. Previously unknown human gut cellulolytic ruminococcal species are highly prevalent in

Updated on:March 28,2024 0

Sci. Adv. | Dijun Chen's group develops a single-cell and spatial transcriptome-based method to identify spatial domains in tumor microenvironment

Updated on: October 09,2024 0

Sci. Adv. | Dijun Chen's group develops a single-cell and spatial transcriptome-based method to identify spatial domains in tumor microenvironment

Updated on:October 09,2024 0

Novel immunometabolism approach pioneers single-cell spatial metabolomics

by Jerry Grillo,Georgia Institute of TechnologyThe scSpaMet pipeline for integratedmetabolite and protein profiling at the single-cell resolution.aOverview of scSpaMet. Tissue

Updated on: December 28,2023 16

Novel immunometabolism approach pioneers single-cell spatial metabolomics

by Jerry Grillo,Georgia Institute of TechnologyThe scSpaMet pipeline for integratedmetabolite and protein profiling at the single-cell resolution.aOverview of scSpaMet. Tissue

Updated on:December 28,2023 16

Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis

by Yale Universitya, Safranin O and Fast Green-stained sections of knee joints of mice with the indicated genotype (n = 8). Scale bar, 50 µm.b–e, OARSI score (b), osteophyte development (c)

Updated on: January 26,2024 11

Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis

by Yale Universitya, Safranin O and Fast Green-stained sections of knee joints of mice with the indicated genotype (n = 8). Scale bar, 50 µm.b–e, OARSI score (b), osteophyte development (c)

Updated on:January 26,2024 11

Experimental drug that alters gut microbiome shows promise for long COVID relief

by Mary Van Beusekom, CIDRAPProportion of PACS symptoms alleviation by six months. Credit:The Lancet Infectious Diseases(2023). DOI: 10.1016/S1473-3099(23)00685-0A randomized controlled tr

Updated on: January 26,2024 8

Experimental drug that alters gut microbiome shows promise for long COVID relief

by Mary Van Beusekom, CIDRAPProportion of PACS symptoms alleviation by six months. Credit:The Lancet Infectious Diseases(2023). DOI: 10.1016/S1473-3099(23)00685-0A randomized controlled tr

Updated on:January 26,2024 8

New antibiotic zosurabalpin shows promise against drug-resistant bacteria: An expert explains

by Jonathan Cox,The ConversationCredit: Pixabay/CC0 Public DomainResearchers haveidentifiedan entirely new class of antibiotic that can kill bacteria that are resistant to most curre

Updated on: January 26,2024 10

New antibiotic zosurabalpin shows promise against drug-resistant bacteria: An expert explains

by Jonathan Cox,The ConversationCredit: Pixabay/CC0 Public DomainResearchers haveidentifiedan entirely new class of antibiotic that can kill bacteria that are resistant to most curre

Updated on:January 26,2024 10

Medicinal plants help keep children healthy in South Africa: 61 species recorded

FEBRUARY 12, 2024by Tshepiso Ndhlovu, Abiodun Olusola Omotayo, Adeyemi Oladapo Aremu and Wilfred Otang-Mbeng,The ConversationThe common yellow commelina, one of the popular plants used to treat

Updated on: March 30,2024 3

Medicinal plants help keep children healthy in South Africa: 61 species recorded

FEBRUARY 12, 2024by Tshepiso Ndhlovu, Abiodun Olusola Omotayo, Adeyemi Oladapo Aremu and Wilfred Otang-Mbeng,The ConversationThe common yellow commelina, one of the popular plants used to treat

Updated on:March 30,2024 3

Smell's sensory magic emerges from mechanism that tailors each of nose's sensory cells, mouse study suggests

byColumbia UniversityThe genome inside an olfactory cell's nucleus is shown as a tangle of color-marked chromosomes with genomic locations of olfactory receptor genes revealed on the right.

Updated on: December 28,2023 18

Smell's sensory magic emerges from mechanism that tailors each of nose's sensory cells, mouse study suggests

byColumbia UniversityThe genome inside an olfactory cell's nucleus is shown as a tangle of color-marked chromosomes with genomic locations of olfactory receptor genes revealed on the right.

Updated on:December 28,2023 18

In the drive to deprescribe, heartburn drug study teaches key lessons

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhether it's costs, safety risks, or "pill fatigue" they're trying to reduce, many health systems and clinics have star

Updated on: April 28,2024 0

In the drive to deprescribe, heartburn drug study teaches key lessons

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhether it's costs, safety risks, or "pill fatigue" they're trying to reduce, many health systems and clinics have star

Updated on:April 28,2024 0

Dapagliflozin cuts cardiovascular events in patients with heart failure, T2D

by Elana GotkineFor patients with heart failure and type 2 diabetes (T2D), dapagliflozin does not reduce urinary albumin-to-creatinine ratio (UACR) but does reduce some cardiovascular events, accordin

Updated on: January 26,2024 13

Dapagliflozin cuts cardiovascular events in patients with heart failure, T2D

by Elana GotkineFor patients with heart failure and type 2 diabetes (T2D), dapagliflozin does not reduce urinary albumin-to-creatinine ratio (UACR) but does reduce some cardiovascular events, accordin

Updated on:January 26,2024 13