Plozasiran reduces triglyceride levels by 74% at 24 weeks

byAmerican College of CardiologyCredit: CC0 Public DomainIn patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran red

Updated on: April 28,2024 0

Plozasiran reduces triglyceride levels by 74% at 24 weeks

byAmerican College of CardiologyCredit: CC0 Public DomainIn patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran red

Updated on:April 28,2024 0

Study finds new treatment makes patients with life-threatening muscle weakness stronger

byAarhus UniversityCredit: Unsplash/CC0 Public DomainFor the thousands of people globally affected by the disease myasthenia gravis (MG), everyday activities become a struggle, and in severe cas

Updated on: March 28,2024 0

Study finds new treatment makes patients with life-threatening muscle weakness stronger

byAarhus UniversityCredit: Unsplash/CC0 Public DomainFor the thousands of people globally affected by the disease myasthenia gravis (MG), everyday activities become a struggle, and in severe cas

Updated on:March 28,2024 0

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Updated on: March 28,2024 0

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Updated on:March 28,2024 0

Patients with device-detected atrial fibrillation and multiple comorbidities do not benefit from anticoagulation: Study

by Angelika Leute, Kompetenznetz Vorhofflimmern e.V. (AFNET)Credit:European Heart Journal(2024). DOI: 10.1093/eurheartj/ehae225In patients with device-detected atrial fibrillation and a hi

Updated on: April 28,2024 0

Patients with device-detected atrial fibrillation and multiple comorbidities do not benefit from anticoagulation: Study

by Angelika Leute, Kompetenznetz Vorhofflimmern e.V. (AFNET)Credit:European Heart Journal(2024). DOI: 10.1093/eurheartj/ehae225In patients with device-detected atrial fibrillation and a hi

Updated on:April 28,2024 0

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Updated on: April 28,2024 0

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Updated on:April 28,2024 0

Researchers race to develop Paxlovid replacement

by Andrew Smith,Rutgers UniversityX-ray crystal structure of the covalent inhibitor Jun11313 with SARS-CoV-2 PLproand structure-based design of biarylphenyl SARS-CoV-2 PLproinhibitor

Updated on: January 26,2024 18

Researchers race to develop Paxlovid replacement

by Andrew Smith,Rutgers UniversityX-ray crystal structure of the covalent inhibitor Jun11313 with SARS-CoV-2 PLproand structure-based design of biarylphenyl SARS-CoV-2 PLproinhibitor

Updated on:January 26,2024 18

New species of bacteria discovered in unusual human infection

JANUARY 18, 2024byKing's College LondonHalf body FDG PET aorto – bi – iliac graft with uptake in the left periureteric region. Credit:Clinical Infection in Practice(2023). DOI: 1

Updated on: March 30,2024 6

New species of bacteria discovered in unusual human infection

JANUARY 18, 2024byKing's College LondonHalf body FDG PET aorto – bi – iliac graft with uptake in the left periureteric region. Credit:Clinical Infection in Practice(2023). DOI: 1

Updated on:March 30,2024 6

A California panel is holding up studies on psychedelics: Some researchers want it gone

JANUARY 19, 2024by Emily Alpert Reyes, Los Angeles TimesCredit: Pixabay/CC0 Public DomainAt the Pacific Neuroscience Institute in Santa Monica, scientists are eager to explore whether a psychedelic ch

Updated on: March 15,2024 8

A California panel is holding up studies on psychedelics: Some researchers want it gone

JANUARY 19, 2024by Emily Alpert Reyes, Los Angeles TimesCredit: Pixabay/CC0 Public DomainAt the Pacific Neuroscience Institute in Santa Monica, scientists are eager to explore whether a psychedelic ch

Updated on:March 15,2024 8

FDA approves oral Duvyzat for Duchenne muscular dystrophy

by Lori SolomonThe U.S. Food and Drug Administration has approved Duvyzat (givinostat) as an oral medication for the treatment of Duchenne muscular dystrophy (DMD) in patients six years of age and old

Updated on: March 28,2024 0

FDA approves oral Duvyzat for Duchenne muscular dystrophy

by Lori SolomonThe U.S. Food and Drug Administration has approved Duvyzat (givinostat) as an oral medication for the treatment of Duchenne muscular dystrophy (DMD) in patients six years of age and old

Updated on:March 28,2024 0

Severe irritability in children and teens: A new understanding

Updated on: October 31,2024 0

Severe irritability in children and teens: A new understanding

Updated on:October 31,2024 0

AlphaFold: The making of a scientific breakthrough

The inside story of the DeepMind team of scientists and engineers who created AlphaFold, an AI system that is recognised as a solution to "protein folding", a grand scientific challenge for more than 50 years.

Updated on: October 16,2024 0

AlphaFold: The making of a scientific breakthrough

The inside story of the DeepMind team of scientists and engineers who created AlphaFold, an AI system that is recognised as a solution to "protein folding", a grand scientific challenge for more than 50 years.

Updated on:October 16,2024 0

Mantle cell lymphoma patients see improved outcomes with oral combination of ibrutinib and venetoclax

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (

Updated on: January 26,2024 7

Mantle cell lymphoma patients see improved outcomes with oral combination of ibrutinib and venetoclax

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (

Updated on:January 26,2024 7