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Medical research
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Many antibiotic courses for common infections not in line with guidelines

Many antibiotic courses for common infections not in line with guidelines

by British Medical JournalCredit: CC0 Public DomainMany antibiotic courses prescribed for common infections treated in English primary care (general practices and community services) exceed the r

Many antibiotic courses for common infections not in line with guidelines

by British Medical JournalCredit: CC0 Public DomainMany antibiotic courses prescribed for common infections treated in English primary care (general practices and community services) exceed the r
Researchers reveal mechanisms of alarmin release at an early stage of immune reaction

Researchers reveal mechanisms of alarmin release at an early stage of immune reaction

byLudwig Maximilian University of MunichSchematic of the experimental design; PBMCs, peripheral blood mononuclear cells. Credit:Nature Immunology(2023). DOI: 10.1038/s41590-023-01656

Researchers reveal mechanisms of alarmin release at an early stage of immune reaction

byLudwig Maximilian University of MunichSchematic of the experimental design; PBMCs, peripheral blood mononuclear cells. Credit:Nature Immunology(2023). DOI: 10.1038/s41590-023-01656
Optimal timing maximizes Paxlovid benefits for treating COVID-19

Optimal timing maximizes Paxlovid benefits for treating COVID-19

byeLifeCredit: CC0 Public DomainResearchers have described the optimal timing for COVID-19 patients to take the antiviral, Paxlovid, to get the most benefit from the treatment, according to a st

Optimal timing maximizes Paxlovid benefits for treating COVID-19

byeLifeCredit: CC0 Public DomainResearchers have described the optimal timing for COVID-19 patients to take the antiviral, Paxlovid, to get the most benefit from the treatment, according to a st
Medicinal herb found to inhibit acetylation of eNOS in vascular dysfunction

Medicinal herb found to inhibit acetylation of eNOS in vascular dysfunction

by Impact Journals LLCAGE enhances endothelial relaxation in aorta rings. (A) Representative traces under specified conditions. (B) Percentage of relaxation proportional to Ach concentration. (C) Maxi

Medicinal herb found to inhibit acetylation of eNOS in vascular dysfunction

by Impact Journals LLCAGE enhances endothelial relaxation in aorta rings. (A) Representative traces under specified conditions. (B) Percentage of relaxation proportional to Ach concentration. (C) Maxi
Imetelstat leads to durable red blood cell transfusion independence

Imetelstat leads to durable red blood cell transfusion independence

by Elana GotkineFor heavily transfused patients with lower-risk myelodysplastic syndromes (LR-MDS) who are not responding to or are ineligible for erythropoiesis-stimulating agents (ESAs), the competi

Imetelstat leads to durable red blood cell transfusion independence

by Elana GotkineFor heavily transfused patients with lower-risk myelodysplastic syndromes (LR-MDS) who are not responding to or are ineligible for erythropoiesis-stimulating agents (ESAs), the competi
Study finds moderately elevated fracture risk following use of sedative–hypnotics

Study finds moderately elevated fracture risk following use of sedative–hypnotics

byThe University of Hong KongCredit: Unsplash/CC0 Public DomainGlobal consumption data show that there is an increasing trend of sedative–hypnotic prescriptions, especially in more developed aff

Study finds moderately elevated fracture risk following use of sedative–hypnotics

byThe University of Hong KongCredit: Unsplash/CC0 Public DomainGlobal consumption data show that there is an increasing trend of sedative–hypnotic prescriptions, especially in more developed aff
Research team discovers potential Alzheimer's drug

Research team discovers potential Alzheimer's drug

FEBRUARY 6, 2024by University of Arkansas for Medical SciencesMolecular docking predicts a CLEAR DNA-binding region in ApoE4. a The DNA-binding region of ApoE4, as defined by molecular modeling. b The

Research team discovers potential Alzheimer's drug

FEBRUARY 6, 2024by University of Arkansas for Medical SciencesMolecular docking predicts a CLEAR DNA-binding region in ApoE4. a The DNA-binding region of ApoE4, as defined by molecular modeling. b The
The fate of drug discovery in academia: Why is it so difficult?

The fate of drug discovery in academia: Why is it so difficult?

FEBRUARY 5, 2024by Impact Journals LLCA typical drug discovery and development strategy. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28552A new editorial paper titled "The fate

The fate of drug discovery in academia: Why is it so difficult?

FEBRUARY 5, 2024by Impact Journals LLCA typical drug discovery and development strategy. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28552A new editorial paper titled "The fate
Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

byJohns Hopkins University School of MedicineNeuronal membrane proteasomes are labeled with a red compound and appear in a subset of sensory neurons that are labeled with green compound. Note, n

Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

byJohns Hopkins University School of MedicineNeuronal membrane proteasomes are labeled with a red compound and appear in a subset of sensory neurons that are labeled with green compound. Note, n
FGF-2 found to promote periodontal healing in an osteoporosis model rat

FGF-2 found to promote periodontal healing in an osteoporosis model rat

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Pixabay/CC0 Public DomainA study investigating the effects of local application of fibroblast growth factor (FGF-2) on p

FGF-2 found to promote periodontal healing in an osteoporosis model rat

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Pixabay/CC0 Public DomainA study investigating the effects of local application of fibroblast growth factor (FGF-2) on p