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Medical research
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New monoclonal antibody for treating cerebral ischemia injury

New monoclonal antibody for treating cerebral ischemia injury

FEBRUARY 27, 2024byThe University of Hong KongProfessor Ruby Hoo Lai-chong (first, right), Department of Pharmacology and Pharmacy of HKUMed, and her research team have successfully developed a

New monoclonal antibody for treating cerebral ischemia injury

FEBRUARY 27, 2024byThe University of Hong KongProfessor Ruby Hoo Lai-chong (first, right), Department of Pharmacology and Pharmacy of HKUMed, and her research team have successfully developed a
Male infertility genetic study improves molecular diagnostics and personalized management of patients

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these
Protein production glitches in Huntington's disease revealed

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe
ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r
FDA Approves Lymphir: A New Hope for CTCL Patients

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.
Enhancing hypoxia-activated prodrug anticancer therapy

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres
New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs
HIV: Early treatment is one key to remission

HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-

HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-
Researchers uncover news clues about the cause of craniofacial birth defects

Researchers uncover news clues about the cause of craniofacial birth defects

byUniversity of Wisconsin-MadisonThis image of a section through the midface of a mouse embryo illustrates fusion of the tissues that form the secondary palate above the tongue. Green staining i

Researchers uncover news clues about the cause of craniofacial birth defects

byUniversity of Wisconsin-MadisonThis image of a section through the midface of a mouse embryo illustrates fusion of the tissues that form the secondary palate above the tongue. Green staining i
A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat
Alcohol may help flush out arsenic from the body, study finds

Alcohol may help flush out arsenic from the body, study finds

by Nanjing Institute of Environmental SciencesGraphical abstract. Credit: Eco-Environment & HealthAstudypublished inEco-Environment & Healthsheds light on the complex i

Alcohol may help flush out arsenic from the body, study finds

by Nanjing Institute of Environmental SciencesGraphical abstract. Credit: Eco-Environment & HealthAstudypublished inEco-Environment & Healthsheds light on the complex i