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Gene editing precisely repairs immune cells

Gene editing precisely repairs immune cells

byMax Delbrück Center for Molecular MedicineMutated T cells are unable to kill B cells (red) induced by the Epstein-Barr virus. This causes other immune cells to flow into the area of infection,

Gene editing precisely repairs immune cells

byMax Delbrück Center for Molecular MedicineMutated T cells are unable to kill B cells (red) induced by the Epstein-Barr virus. This causes other immune cells to flow into the area of infection,
Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin
Scientists explore the coupling between health span and lifespan in Caenorhabditis

Scientists explore the coupling between health span and lifespan in Caenorhabditis

by Impact Journals LLCPotential effects of compounds on lifespan and health. Credit: 2024 Banse et al.A new research paper waspublishedinAgingtitled, "The coupling between

Scientists explore the coupling between health span and lifespan in Caenorhabditis

by Impact Journals LLCPotential effects of compounds on lifespan and health. Credit: 2024 Banse et al.A new research paper waspublishedinAgingtitled, "The coupling between
Novel compound protects against infection by virus that causes COVID-19, preliminary studies show

Novel compound protects against infection by virus that causes COVID-19, preliminary studies show

JANUARY 5, 2024 Editors' notesbyDana-Farber Cancer InstituteDesign and screening of stapled lipopeptide inhibitors of SARS-CoV-2.aSchematic of the six-helix bundle (6-HB) fusion

Novel compound protects against infection by virus that causes COVID-19, preliminary studies show

JANUARY 5, 2024 Editors' notesbyDana-Farber Cancer InstituteDesign and screening of stapled lipopeptide inhibitors of SARS-CoV-2.aSchematic of the six-helix bundle (6-HB) fusion
Simulations reveal mechanism behind protein buildup in Parkinson's disease

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod
Study: This protein may be the 'glue' that helps COVID virus stick

Study: This protein may be the 'glue' that helps COVID virus stick

JANUARY 24, 2024byTulane UniversityCredit: CC0 Public DomainWhen SARS-CoV-2 enters the human body, the virus' spike protein binds to a cell, allowing the virus to infiltrate and begin replic

Study: This protein may be the 'glue' that helps COVID virus stick

JANUARY 24, 2024byTulane UniversityCredit: CC0 Public DomainWhen SARS-CoV-2 enters the human body, the virus' spike protein binds to a cell, allowing the virus to infiltrate and begin replic
Researchers present playbook of best practices for cancer team science in the modern era

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat
'It's the greatest living experiment': Pitt Men's Study marks 40 years of AIDS research

'It's the greatest living experiment': Pitt Men's Study marks 40 years of AIDS research

by Anya Sostek, Pittsburgh Post-GazetteCredit: Pixabay/CC0 Public DomainIn a Pittsburgh hospital in the early 1980s, Charles Rinaldo saw a young, previously healthy gay man critically ill with a virus

'It's the greatest living experiment': Pitt Men's Study marks 40 years of AIDS research

by Anya Sostek, Pittsburgh Post-GazetteCredit: Pixabay/CC0 Public DomainIn a Pittsburgh hospital in the early 1980s, Charles Rinaldo saw a young, previously healthy gay man critically ill with a virus
New guidelines for reporting clinical trials of biofield therapies released

New guidelines for reporting clinical trials of biofield therapies released

byMary Ann Liebert, IncCredit: Unsplash/CC0 Public DomainNewguidelinesfor reporting clinical trials of biofield therapies are presented in theJournal of Integrative and Complem

New guidelines for reporting clinical trials of biofield therapies released

byMary Ann Liebert, IncCredit: Unsplash/CC0 Public DomainNewguidelinesfor reporting clinical trials of biofield therapies are presented in theJournal of Integrative and Complem
The dual role of well-known protein sheds light on Parkinson's disease mechanisms

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th
A new immunologic and endocrine syndrome

A new immunologic and endocrine syndrome

by University of MontrealThese mice are twin, except that the left mouse is normal whereas the Armc5 gene has been invalidated by genetic knockout in the right mouse. The mutated mouse is smaller

A new immunologic and endocrine syndrome

by University of MontrealThese mice are twin, except that the left mouse is normal whereas the Armc5 gene has been invalidated by genetic knockout in the right mouse. The mutated mouse is smaller
Study highlights impact of aldehydes on DNA damage and aging

Study highlights impact of aldehydes on DNA damage and aging

byNagoya UniversityHistones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. Credit: Reiko Matsushi

Study highlights impact of aldehydes on DNA damage and aging

byNagoya UniversityHistones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. Credit: Reiko Matsushi