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Medical research
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How transcription factors influence insulin-producing beta cells

How transcription factors influence insulin-producing beta cells

JANUARY 31, 2024by Melissa Rohman,Northwestern UniversityCredit:Cell Metabolism(2024). DOI: 10.1016/j.cmet.2023.11.018A recent study from the laboratory of Joseph Bass, MD, Ph.D., th

How transcription factors influence insulin-producing beta cells

JANUARY 31, 2024by Melissa Rohman,Northwestern UniversityCredit:Cell Metabolism(2024). DOI: 10.1016/j.cmet.2023.11.018A recent study from the laboratory of Joseph Bass, MD, Ph.D., th
Multi-generational toxicant exposures show cumulative, inherited health effects

Multi-generational toxicant exposures show cumulative, inherited health effects

JANUARY 23, 2024byWashington State UniversityDMR identification. The number of DMRs found using different P-value cutoff thresholds. The All-Window column shows all DMRs. The Multiple Window col

Multi-generational toxicant exposures show cumulative, inherited health effects

JANUARY 23, 2024byWashington State UniversityDMR identification. The number of DMRs found using different P-value cutoff thresholds. The All-Window column shows all DMRs. The Multiple Window col
New insights on kidney disease in African Americans could lead to therapies

New insights on kidney disease in African Americans could lead to therapies

by Sarah Avery,Duke UniversityCredit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI172262In a finding that could help reduce the racial disparity in kidney disease, Duke H

New insights on kidney disease in African Americans could lead to therapies

by Sarah Avery,Duke UniversityCredit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI172262In a finding that could help reduce the racial disparity in kidney disease, Duke H
Dogs may provide new insights into human aging and cognition

Dogs may provide new insights into human aging and cognition

by Eötvös Loránd UniversityThe quest to understand intelligence and unravel the workings of the mind has always been considered the holy grail of natural sciences. While we're still uncoverin

Dogs may provide new insights into human aging and cognition

by Eötvös Loránd UniversityThe quest to understand intelligence and unravel the workings of the mind has always been considered the holy grail of natural sciences. While we're still uncoverin
Developing standards for organ-on-a-chip research

Developing standards for organ-on-a-chip research

FEBRUARY 22, 2024by Jennifer Lauren Lee,National Institute of Standards and TechnologyOrgan-on-a-chip devices use tiny structures called microfluidic channels to bring small, controlled amounts

Developing standards for organ-on-a-chip research

FEBRUARY 22, 2024by Jennifer Lauren Lee,National Institute of Standards and TechnologyOrgan-on-a-chip devices use tiny structures called microfluidic channels to bring small, controlled amounts
Researchers discover a potential cause of Parkinson's disease

Researchers discover a potential cause of Parkinson's disease

MAY 5, 2023byUniversity of HelsinkiAggregation of alpha-synuclein in a nerve cell. Credit: Timo Myöhänen research groupThere are currently 8 million patients with Parkinson's disease in the

Researchers discover a potential cause of Parkinson's disease

MAY 5, 2023byUniversity of HelsinkiAggregation of alpha-synuclein in a nerve cell. Credit: Timo Myöhänen research groupThere are currently 8 million patients with Parkinson's disease in the
Researchers discover a new role for a protein that helps form memories

Researchers discover a new role for a protein that helps form memories

by Marya Barlow,Virginia Tech(From left) Research scientist Kayla Farrell and Associate Professor Tim Jarome in the School of Animal Sciences are part of a Virginia Tech research team that disco

Researchers discover a new role for a protein that helps form memories

by Marya Barlow,Virginia Tech(From left) Research scientist Kayla Farrell and Associate Professor Tim Jarome in the School of Animal Sciences are part of a Virginia Tech research team that disco
Researchers identify peptides produced by the proteasome that degrade damaged proteins

Researchers identify peptides produced by the proteasome that degrade damaged proteins

FEBRUARY 14, 2024by Carmen Rotte,Max Planck SocietyUsing innovative computer programs and biochemical experiments, researchers identified and quantified fragments that the cellular garbage dispo

Researchers identify peptides produced by the proteasome that degrade damaged proteins

FEBRUARY 14, 2024by Carmen Rotte,Max Planck SocietyUsing innovative computer programs and biochemical experiments, researchers identified and quantified fragments that the cellular garbage dispo
Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec
Biological engineers discover why a promising drug failed in clinical trials

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima
Cockayne syndrome: New insights into cellular DNA repair mechanism

Cockayne syndrome: New insights into cellular DNA repair mechanism

byLudwig Maximilian University of MunichDPC-seq enables genome-wide mapping of DPC induction and resolution. An overview of the DPC-seq methodology. Cultured cells are treated with 1.75 mM forma

Cockayne syndrome: New insights into cellular DNA repair mechanism

byLudwig Maximilian University of MunichDPC-seq enables genome-wide mapping of DPC induction and resolution. An overview of the DPC-seq methodology. Cultured cells are treated with 1.75 mM forma